Relationship between C-reactive protein and early activation of leukocytes indicated by leukocyte antisedimentation rate (LAR) in patients with acute cerebrovascular events

Clinical Hemorheology and Microcirculation

Volumn 44, Issue 3, 2010, Pages 183-192

  Molnar, Tihamer ^a   Papp, Viktoria ^a   Banati, Miklos ^a   Szereday, Laszlo ^a   Pusch, Gabriella ^a   Szapary, Laszlo ^a   Bogar, Lajos ^a   Illes, Zsolt ^a  

^a UNIVERSITY OF PÉCS   (Hungary)

Author keywords

CRP; leukocytes; outcome of stroke; post stroke infection; Stroke

Indexed keywords

C REACTIVE PROTEIN; PROTEIN S100B; NERVE GROWTH FACTOR; PROTEIN S 100; S100B PROTEIN, HUMAN;

ADULT; AGED; ARTICLE; BRAIN INFARCTION; BRAIN INFECTION; BRAIN ISCHEMIA; CEREBROVASCULAR DISEASE; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE SEVERITY; FEMALE; HUMAN; INJURY SEVERITY; LEUKOCYTE ACTIVATION; MACROGLIA; MALE; PROTEIN BLOOD LEVEL; RECURRENT DISEASE; SEDIMENTATION RATE; TRANSIENT ISCHEMIC ATTACK; BLOOD; CEREBROVASCULAR ACCIDENT; ERYTHROCYTE SEDIMENTATION RATE; LEUKOCYTE; METABOLISM; MIDDLE AGED; PROGNOSIS; RISK FACTOR;

AGED; BLOOD SEDIMENTATION; BRAIN ISCHEMIA; C-REACTIVE PROTEIN; FEMALE; HUMANS; LEUKOCYTES; MALE; MIDDLE AGED; NERVE GROWTH FACTORS; PROGNOSIS; RISK FACTORS; S100 CALCIUM BINDING PROTEIN BETA SUBUNIT; S100 PROTEINS; STROKE;

EID: 77954127491     PISSN: 13860291     EISSN: None     Source Type: Journal    
DOI: 10.3233/CH-2010-1273     Document Type: Article

References (32)

1. N.B. Beamer, B.M. Coull, W.M. Clark, J.S. Hazel and J.R. Silberger, Interleukin-6 and interleukin-1 receptor antagonist in acute stroke, Ann Neurol 37 (1995), 800-805.
2. L. Bogar, Z. Molnar, P. Kenyeres and P. Tarsoly, Sedimentation characteristics of leukocytes can predict bacteremia in critical care patients, J Clin Path 59 (2006), 523-525.
3. L. Bogar and M. Tekeres, Leukocyte flotation during gravity sedimentation of the whole blood, Clin Hemorheol Microcirc 22 (2000), 29-33.
4. L. Bogar, P. Tarsoly and P. Jakso, Characteristics of light and heavy polymorphonuclear leukocytes, Clin Hemorheol Microcirc 27 (2002), 149-153.
5. A. Chamorro, S. Amaro, M. Vargas, V. Obach, A. Cervera, M. Gómez-Choco, F. Torres and A.M. Planas, Catecholamines, infection, and death in acute ischemic stroke, J Neurol Sci 252 (2007), 29-35.
6. H. Christensen and G. Boysen, C-reactive protein and white blood cell count increases in the first 24 hours after acute stroke, Cerebrovasc Dis 18 (2004), 214-219.
7. J. Cohen and C. Brun-Bruisson, A. Torres, et al., Diagnosis of infection in sepsis: an evidence-based review, Crit Care Med 32 (2004), S466-494.
8. R.J. Davenport, M.S. Dennis, I. Wellwood and C.P. Warlow, Complications after acut stroke, Stroke 27 (1996), 415-420.
9. M. Di Napoli, F. Papa and V. Bocola, C-reactive protein in ischemic stroke, Stroke 32 (2001), 917-924.
10. M. Di Napoli, F. Papa and V. Bocola, Prognostic influence of increased C-reactive protein and fibrinogen levels in ischemic stroke, Stroke 32 (2001), 133-138. (Pubitemid 32063837)
11. A.M. Elneihoum, P. Falke, B. Hedblad, F. Lindgärde and K. Ohlsson, Leukocyte activation in atherosclerosis: correlation with risk factors, Atherosclerosis 131 (1997), 79-84.
12. European stroke initiative recommendations for stroke management - Update 2003, Cerebrovasc Dis 16 (2003), 311-337.
13. P. Falke, A.M. Elneihoum and K. Ohlsson, Leukocyte activation: relation to cardiovascular mortality after cerebrovascular ischemia, Cerebrovasc Dis 10 (2000), 97-101.
14. E.S. Ford and W.H. Giles, Serum C-reactive protein and self-reported stroke. Findings from the third national health and nutrition examination survey, Arterioscler Thromb Vasc Biol 20 (2000), 1052-1056.
15. A.J. Grau, F. Buggle, P. Schnitzler, M. Spiel, C. Lichy and W. Hacke, Fever and infection early after ischemic stroke, J Neurol Sci 171 (1999), 115-120.
16. D.G. Haider, N. Leuchten, G. Schaller, G. Gouya, J. Kolodjaschna, L. Schmetterer, S. Kapiotis and M. Wolzt, C-reactive protein is expressed and secreted by peripheral blood mononuclear cells, Clin Exp Immun 146(3) (2006), 533-539.
17. T. Ito and U. Ikeda, Inflammatory cytokines and cardiovascular disease, Curr Drug Targets In.amm Allergy 2 (2003), 257-265.
18. K.C. Johnston, J.Y. Li, P.D. Lyden, S.K. Hanson, T.E. Feasby, R.J. Adams, R.E. Faught Jr and E.C. Haley Jr, Medical and neurological complications of ischemic stroke: experience from the RANTTAS trial. RANTTAS investigators, Stroke 29 (1998), 447-453.
19. J. Krupinski, M.M. Turu, M. Slevin and J. Martínez- González, Carotid plaque, stroke pathogenesis, and CRP: treatment of ischemic stroke, Curr Cardiol Rep 10 (2008), 25-30.
20. P. Langhorne, D.J. Stott, L. Robertson, J. MacDonald, L. Jones, C. McAlpine, F. Dick, G.S. Taylor and G. Murray, Medical complications after stroke: a multicenter study, Stroke 31 (2000), 1223-1229.
21. T. Molnar, A. Peterfalvi, L. Szereday, G. Pusch, L. Szapary, S. Komoly, L. Bogar and Z. Illes, Deficient leukocyte antisedimentation is related to post-stroke infections and outcome, J Clin Path 61 (2008), 1209-1213.
22. R.F. Mortensen, C-reactive protein, inflammation and innate immunity, Immunol Res 24 (2001), 163-176.
23. K.W. Muir, C.J. Weir, W. Alwan, I.B. Squire and K.R. Lees, C-reactive protein and outcome after ischemic stroke, Stroke 30 (1999), 981-985.
24. N. S. Rost, P.A. Wolf, C.S. Kase, M. Kelly-Hayes, H. Silbershatz, J.M. Massaro, R.B. D'Agostino, C. Franzblau and P.W.F. Wilson, Plasma concentration of C-reactive protein and risk of ischemic stroke and transient ischemic attack. The framingham study, Stroke 32 (2001), 2575-2579.
25. H. Sun, T. Koike, T. Ichikawa, K. Hatakeyama, M. Shiomi, B. Zhang, S. Kitajima, M. Morimoto, T. Watanabe, Y. Asada, Y.E. Chen and J. Fan, C-reactive protein in atherosclerotic lesions: its origin and pathophysiological significance, Am J Pathol 167 (2005), 1139-1148.
26. D. Tanne, M. Benderly, U. Goldbourt, M. Haim, A. Tenebaum, E.Z. Fisamn, Z. Matas, Y. Adler, R. Zimmlichman and S. Behar, C-reactive protein as a predictor of incident ischemic stroke among patients with preexisting cardiovascular disease, Stroke 37 (2006), 1720-1724.
27. T. Thom, N. Haase, W. Rosamond, V.J. Howard, J. Rumsfeld, T. Manolio, et al., Heart disease and stroke statistics- 2006 update: A report from the American Heart Assocoation Statistics Committee and Stroke Statistics Subcommittee, Circulation 113 (2006), 85-151.
28. I.Velcheva and G. Nikolova, Hemorheological disturbances and cognitive function in patients with cerebrovascular disease. Clin Hemorheol Microcirc 39 (2008), 397-402.
29. S. Verma, C-reactive protein incites atherosclerosis, Can J Cardiol 20 (2004), 29B-31B.
30. S. Verma, S.H. Li, M.V. Badiwala, et al., Endothelin antagonism and interleukin-6 inhibition attenuates the proatherogenic effects of C-reactive protein, Circulation 105 (2002), 1890-1896.
31. S. Verma, C.H. Wang, S.H. Li, et al., A self-fulfilling prophecy: C-reactive protein attenuated nitric oxide production and inhibits angiogenesis, Circulation 106 (2002), 913-919.
32. N. Vila, J. Castillo, A. Davalos and A. Chamorro, Proinflammatory cytokines and early neurological worsening in ischemic stroke, Stroke 31 (2000), 2325-2329.