Repeated colonoscopic screening of patients with acromegaly: 15-Year experience identifies those at risk of new colonic neoplasia and allows for effective screening guidelines

European Journal of Endocrinology

Volumn 163, Issue 1, 2010, Pages 21-28

  Dworakowska, D ^a,b   Gueorguiev, M ^a   Kelly, P ^a   Monson, J P ^a   Besser, G M ^a   Chew, S L ^a   Akker, S A ^c   Drake, W M ^c   Fairclough, P D ^c   Grossman, A B ^a   Jenkins, P J ^a  

^a QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

^b MEDICAL UNIVERSITY OF GDANSK   (Poland)

^c BARTS HEALTH NHS TRUST   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

GROWTH HORMONE; SOMATOMEDIN C;

ACROMEGALY; ADULT; ARTICLE; CANCER RISK; CANCER SCREENING; CLINICAL PRACTICE; COLON POLYP; COLONOSCOPY; COLORECTAL CANCER; HUMAN; MAJOR CLINICAL STUDY; MALE; MEDICAL RECORD REVIEW; PRACTICE GUIDELINE; PREVALENCE; PRIORITY JOURNAL; REPEAT PROCEDURE; RETROSPECTIVE STUDY;

ACROMEGALY; ADENOMATOUS POLYPS; AGED; COLON; COLONIC NEOPLASMS; COLONOSCOPY; HUMAN GROWTH HORMONE; HUMANS; INSULIN-LIKE GROWTH FACTOR I; MALE; MIDDLE AGED; RADIOIMMUNOASSAY;

EID: 77954124860     PISSN: 08044643     EISSN: 1479683X     Source Type: Journal    
DOI: 10.1530/EJE-09-1080     Document Type: Article

References (35)

1. Klein I, Parveen G, Gavaler JS & Vanthiel DH. Colonic polyps in patients with acromegaly. Annals of Internal Medicine 1982 97 27-30.
2. Ituarte EM, Petrini J & Hershman JM. Acromegaly and colon cancer. Annals of Internal Medicine 1984 101 627-628.
3. Brunner JE, Johnson CC, Zafar S, Peterson EL, Brunner JF & Mellinger RC. Colon cancer and polyps in acromegaly: increased risk associated with family history of colon cancer. Clinical Endocrinology 1990 32 65-71. (Pubitemid 20029946)
4. Ezzat S, Strom C & Melmed S. Colon polyps in acromegaly. Annals of Internal Medicine 1991 114 754-755.
5. Vasen HF, van Erpecum KJ, Roelfsema F, Raue F, Koppeschaar H, Griffioen G & van Berge Henegouwen GP. Increased prevalence of colonic adenomas in patients with acromegaly. European Journal of Endocrinology 1994 131 235-237. (Pubitemid 24297511)
6. Terzolo M, Tappero G, Borretta G, Asnaghi G, Pia A, Reimondo G, Boccuzzi A, Cesario F, Rovero E, Paccotti P & Angeli A. High prevalence of colonic polyps in patients with acromegaly. Influence of sex and age. Archives of Internal Medicine 1994 154 1272-1276.
7. Ortego J, Vega B, Sampedro J, Escalada J, Boixeda D & Varela C. Neoplastic colonic polyps in acromegaly. Hormone and Metabolic Research 1994 26 609-610.
8. Ladas SD, Thalassinos NC, Ioannides G & Raptis SA. Does acromegaly really predispose to an increased prevalence of gastrointestinal tumours? Clinical Endocrinology 1994 41 597-601.
9. Delhougne B, Deneux C, Abs R, Chanson P, Fierens H, Laurent- Puig P, Duysburgh I, Stevenaert A, Tabarin A & Delwaide J. The prevalence of colonic polyps in acromegaly: a colonoscopic and pathological study in 103 patients. Journal of Clinical Endocrinology and Metabolism 1995 80 3223-3226.
10. Colao A, Balzano A, Ferone D, Panza N, Grande G, Marzullo P, Bove A, Iodice G, Merola B & Lombardi G. Increased prevalence of colonic polyps and altered lymphocyte subset pattern in the colonic lamina propria in acromegaly. Clinical Endocrinology 1997 47 23-28. (Pubitemid 27313984)
11. Jenkins PJ, Fairclough PD, Richards T, Lowe DG, Monson J, Grossman A, Wass JAH & Besser GM. Acromegaly, colonic polyps and carcinoma. Clinical Endocrinology 1997 47 17-22.
12. Terzolo M, Reimondo G, Gasperi M, Cozzi R, Pivonello R, Vitale G, Scillitani A, Attanasio R, Cecconi E, Daffara F, Gaia E, Martino E, Lombardi G, Angeli A & Colao A. Colonoscopic screening and follow-up in patients with acromegaly: a multicenter study in Italy. Journal of Clinical Endocrinology and Metabolism 2005 90 84-90. (Pubitemid 40116638)
13. Muto T, Bussey HJ & Morson BC. The evolution of cancer of the colon and rectum. Cancer 1975 36 2251-2270.
14. Selby JV, Friedman GD, Quesenberry CP & Weiss NS. A case - control study of screening sigmoidoscopy and mortality from colorectal cancer. New England Journal of Medicine 1992 326 653-657.
15. Jass JR. Hyperplastic polyps and colorectal cancer: is there a link? Clinical Gastroenterology and Hepatology 2004 2 1-8.
16. Wynter CV, Walsh MD, Higuchi T, Leggett BA, Young J & Jass JR. Methylation patterns define two types of hyperplastic polyp associated with colorectal cancer. Gut 2004 53 573-580.
17. Atkin WS, Morson BC & Cuzick J. Long-term risk of colorectal cancer after excision of rectosigmoid adenomas. New England Journal of Medicine 1992 326 658-662.
18. Melmed S, Colao A, Barkan A, Molitch M, Grossman AB, Kleinberg D, Clemmons D, Chanson P, Laws E, Schlechte J, Vance ML, Ho K & Giustina A. Guidelines for acromegaly management: an update. Journal of Clinical Endocrinology and Metabolism 2009 94 1509-1517.
19. Jenkins PJ, Frajese V, Jones AM, Camacho-Hubner C, Lowe DG, Fairclough PD, Chew SL, Grossmann AB, Monson J & Besser GM. IGF-I and the development of colorectal neoplasia in acromegaly. Journal of Clinical Endocrinology and Metabolism 2000 85 3218-3221.
20. Morrell DJ, Dadi H, More J, Taylor AM, Dabestani A, Buchanan CR, Holder AT & Preece MA. A monoclonal antibody to human insulin-like growth factor-I: characterization, use in radio-immunoassay and effect on the biological activities of the growth factor. Journal of Molecular Endocrinology 1989 2 201-206. (Pubitemid 19117456)
21. Ezzat S & Melmed S. Clinical review 18: are patients with acromegaly at increased risk for neoplasia? Journal of Clinical Endocrinology and Metabolism 1991 72 245-249.
22. Jenkins PJ & Besser M. Clinical perspective: acromegaly and cancer: a problem. Journal of Clinical Endocrinology and Metabolism 2001 86 2935-2941. (Pubitemid 32673444)
23. Turner HE &Wass JA. Modern approaches to treating acromegaly. Quarterly Journal of Medicine 2000 93 1-6.
24. Renehan AG, Bhaskar P, Painter JE, O'Dwyer ST, Haboubi N, Varma J, Ball SG & Shalet SM. The prevalence and characteristics of colorectal neoplasia in acromegaly. Journal of Clinical Endocrinology and Metabolism 2000 85 3417-3424.
25. Renehan AG, O'Dwyer ST & Shalet SM. Guidelines for colonoscopic screening in acromegaly are inconsistent with those for other high risk groups. Gut 2003 52 1071-1072.
26. Loeper S & Ezzat S. Acromegaly: re-thinking the cancer risk. Reviews in Endocrine and Metabolic Disorders 2008 9 41-58.
27. Rokkas T, Pistiolas D, Sechopoulos P, Margantinis G & Koukoulis G. Risk of colorectal neoplasm in patients with acromegaly: a meta-analysis. World Journal of Gastroenterology 2008 14 3484-3489.
28. Fraser GM & Niv Y. Hyperplastic polyp and colonic neoplasia: is there an association? Journal of Clinical Gastroenterology 1993 16 278-280.
29. Cats A, Dullaart RP, Kleibeuker JH, Kuipers F, Sluiter WJ, Hardonk MJ & de Vries EG. Increased epithelial cell proliferation in the colon of patients with acromegaly. Cancer Research 1996 56 523-526. (Pubitemid 26043650)
30. Bogazzi F, Cosci C, Sardella C, Costa A, Manetti L, Gasperi M, Rossi G, Bartalena L & Martino E. Identification of acromegalic patients at risk of developing colonic adenomas. Journal of Clinical Endocrinology and Metabolism 2006 91 1351-1356.
31. Manousos O, Souglakos J, Bosetti C, Tzonou A, Chatzidakis V, Trichopoulos D, Adami HO & Mantzoros C. IGF-I and IGF-II in relation to colorectal cancer. International Journal of Cancer 1999 83 15-17. (Pubitemid 29409470)
32. Ma J, Pollak M, Giovannucci E, Chan JM, Tao Y, Hennekens CH & Stampfer MJ. Prospective study of colorectal cancer risk in men and plasma levels of insulin like growth factor (IGF)-1 and IGF-binding protein-3. Journal of the National Cancer Institute 1999 91 620-625. (Pubitemid 29194048)
33. Bogazzi F, Ultimieri F, Raggi F, Russo D, Vanacore R, Guida C, Brogioni S, Cosci C, Gasperi M, Bartalena L & Martino E. Growth hormone inhibits apoptosis in human colonic cancer cell lines: antagonistic effects of peroxisome proliferator activated receptor-gamma ligands. Endocrinology 2004 145 3353-3362. (Pubitemid 38830007)
34. Bensen SP, Cole BF, Mott LA, Baron JA, Sandler RS & Haile R. Colorectal hyperplastic polyps and risk of recurrence of adenomas and hyperplastic polyps. Polyps Prevention Study. Lancet 1999 354 1873-1874.
35. Levin B, Lieberman DA, McFarland B, Smith RA, Brooks D, Andrews KS, Dash C, Giardiello FM, Glick S, Levin TR, Pickhardt P, Rex DK, Thorson A & Winawer SJ. Screening and surveillance for the early detection of colorectal cancer and adenomatous polyps, 2008: a joint guideline from the American Cancer Society, the US Multi-Society Task Force on Colorectal Cancer, and the American College of Radiology. CA: A Cancer Journal for Clinicians 2008 58 130-160.