Insulin-like growth factor I and the development of colorectal neoplasia in acromegaly

Journal of Clinical Endocrinology and Metabolism

Volumn 85, Issue 9, 2000, Pages 3218-3221

  Jenkins, P J ^a   Frajese, V ^a   Jones, A M ^a   Camacho Hubner, C ^a   Lowe, D G ^a   Fairclough, P D ^a   Chew, S L ^a   Grossman, A B ^a   Monson, J P ^a   Besser, G M ^a  

^a ST BARTHOLOMEW S HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

GROWTH HORMONE; SOMATOMEDIN C;

ACROMEGALY; ADULT; AGED; ARTICLE; COLON POLYP; COLORECTAL TUMOR; HUMAN; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; RADIOIMMUNOASSAY; RISK FACTOR; SCREENING;

EID: 0033678447     PISSN: 0021972X     EISSN: None     Source Type: Journal    
DOI: 10.1210/jc.85.9.3218     Document Type: Article

References (31)

1. Colonic polyps in patients with acromegaly
2. Acromegaly and cancer
3. Acromegaly and colon cancer
4. Acromegaly and gastrointestinal adenocarcinomas
5. Colon cancer and polyps in acromegaly: Increased risk associated with family history of colon cancer
6. Benign and malignant tumors in patients with acromegaly
7. Colon polyps in acromegaly
8. Clinical review 18: Are patients with acromegaly at increased risk for neoplasia?
9. Gastrointestinal tumors in acromegalic patients
10. Acromegaly and gastrointestinal
11. Colonic polyps in acromegaly
12. Increased prevalence of colonic adenomas in patients with acromegaly
13. High prevalence of colonic polyps in patients with acromegaly. Influence of sex and age
14. Neoplastic colonic polyps in acromegaly
15. The prevalence of colonic polyps in acromegaly: A colonoscopic and pathological study in 103 patients
16. Increased prevalence of colonic polyps and altered lymphocyte subset pattern in the colonic lamina propria in acromegaly
17. Prevalence of colorectal carcinoma and polyps in acromegaly
18. Acromegaly, colonic polyps and carcinoma
19. The evolution of cancer of the colon and rectum
20. A genetic model for colorectal tumorigenesis
21. Long-term risk of colorectal cancer after excision of rectosigmoid adenomas
22. Prevention of colorectal cancer by once-only sigmoidoscopy
23. Prevention of colorectal cancer by colonoscopic polypectomy. The National Polyp Study Workgroup
24. Prolonged large bowel transit increases serum deoxycholic acid: A risk factor for octreotide induced gallstones
25. Acromegaly is associated with colonomegaly which correlates with tissue exposure to growth hormone and may be implicated in their increased risk of colorectal neoplasia
26. A monoclonal antibody to human insulin-like growth factor-I: Characterization, use in radioimmunoassay and effect on the biological activities of the growth factor
27. Prospective study of colorectal cancer risk in men and plasma levels of insulin like growth factor (IGF)-1 and IGF-binding protein-3
28. Increased epithelial cell proliferation in the colon of patients with acromegaly
29. The pathogenesis of colorectal neoplasia in acromegaly
30. Co-stimulation of gastrointestinal tumour cell growth by gastrin, transforming growth factor α and insulin like growth factor-I
31. Growth regulation and co-stimulation of human colorectal cancer cell lines by insulin-like growth factor I, II and transforming growth factor α