Antidepressant effects of the extract YZ-50 from Polygala tenuifolia in chronic mild stress treated rats and its possible mechanisms

Pharmaceutical Biology

Volumn 48, Issue 7, 2010, Pages 794-800

  Hu, Yuan ^a   Liu, Ping ^a   Guo, Dai Hong ^a   Rahman, Khalid ^b   Wang, Dong Xiao ^a   Xie, Ting Ting ^a  

^a CHINESE PLA GENERAL HOSPITAL   (China)

^b LIVERPOOL JOHN MOORES UNIVERSITY   (United Kingdom)

Author keywords

BDNF; Corticosterone; Hippocampus; Polygala tenuifolia

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; DESIPRAMINE; HERBACEOUS AGENT; MESSENGER RNA; POLYGALA TENUIFOLIA EXTRACT; POLYSORBATE 80; UNCLASSIFIED DRUG; YZ 50;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIDEPRESSANT ACTIVITY; ARTICLE; CHRONIC STRESS; CONTROLLED STUDY; CORTICOSTERONE BLOOD LEVEL; DEPRESSION; DRUG ISOLATION; DRUG MECHANISM; HIPPOCAMPUS; HYPOPHYSIS ADRENAL SYSTEM; MALE; NEUROPROTECTION; NONHUMAN; OPEN FIELD BEHAVIOR; PLANT ROOT; POLYGALA TENUIFOLIA; POLYGALACEAE; RAT; SUGAR INTAKE;

ADRENOCORTICOTROPIC HORMONE; ANIMALS; ANTIDEPRESSIVE AGENTS; BRAIN-DERIVED NEUROTROPHIC FACTOR; CORTICOSTERONE; DEPRESSION; DRUG EVALUATION, PRECLINICAL; DRUGS, CHINESE HERBAL; HIPPOCAMPUS; MALE; MOTOR ACTIVITY; PHYTOTHERAPY; PLANT EXTRACTS; POLYGALACEAE; RANDOM ALLOCATION; RATS; RATS, SPRAGUE-DAWLEY; STRESS, PSYCHOLOGICAL; WEIGHT GAIN;

POLYGALA TENUIFOLIA; POLYGALACEAE; RATTUS;

EID: 77954122271     PISSN: 13880209     EISSN: 17445116     Source Type: Journal    
DOI: 10.3109/13880200903280034     Document Type: Article

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