Phosphodiesterase 4D (PDE4D) gene variants and risk of ischemic stroke in the Taiwanese population

Laboratory Medicine

Volumn 40, Issue 2, 2009, Pages 87-90

  Hsieh, Ming Song ^a,b   Yu, Shu Chuan ^a   Chung, Wing Ten ^a   Hsueh, Yu Mei ^a   Chen, Feng Chia ^a   Chiu, Wen Ta ^a   Lee, Horng Mo ^b  

^a TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^b TAIPEI MEDICAL UNIVERSITY   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

PHOSPHODIESTERASE 4D; PHOSPHODIESTERASE IV; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; BRAIN ISCHEMIA; CONTROLLED STUDY; DNA SEQUENCE; FEMALE; GENETIC ANALYSIS; GENETIC ASSOCIATION; GENETIC RISK; GENETIC VARIABILITY; GENOTYPE; HUMAN; MAJOR CLINICAL STUDY; MALE; POLYMERASE CHAIN REACTION; POPULATION GENETICS; RISK ASSESSMENT; SINGLE NUCLEOTIDE POLYMORPHISM; TAIWAN;

EID: 77953974426     PISSN: 00075027     EISSN: 19437730     Source Type: Journal    
DOI: 10.1309/LM4X5PCRN4AECXBB     Document Type: Article

References (22)

1. Donnan GA, Fisher M, Macleod M, et al. Stroke. Lancet. 2008;371:1612-1623.
2. Huang ZS, Chiang TL, Lee TK. Stroke prevalence in Taiwan. Findings from the 1994 National Health Interview Survey. Stroke. 1997;28:1579-1584.
3. Caplan LR Diagnosis and treatment of ischemic stroke. JAMA. 1991;266:2413-2418.
4. Jeng, JS, Lee TK, Chang YC, et al. Subtypes and case-fatality rates of stroke: A hospital-based stroke registry in Taiwan (SCAN-IV). J Neurol Sci. 1998;156:220-226. (Pubitemid 28186478)
5. Dichgans M, Markus HS. Genetic association studies in stroke: Methodological issues and proposed standard criteria. Stroke. 2005;36:2027-2031.
6. Jamrozik K, Broadhurst RJ, Anderson CS, et al. The role of lifestyle factors in the etiology of stroke. A population-based case-control study in Perth, Western Australia. Stroke. 1994;25:51-59. (Pubitemid 24977183)
7. Gretarsdottir S, Sveinbjornsdottir S, Jonsson HH, et al. Localization of a susceptibility gene for common forms of stroke to 5q12. Am J Hum Genet. 2002;70:593-603.
8. Gretarsdottir S, Thorleifsson G, Reynisdottir ST, et al. The gene encoding phosphodiesterase 4D confers risk of ischemic stroke. Nat Genet. 2003;35:131-138.
9. Palmer D, Tsoi K, Maurice DH. Synergistic inhibition of vascular smooth muscle cell migration by phosphodiesterase 3 and phosphodiesterase 4 inhibitors. Circ Res. 1998;82:852-861. (Pubitemid 28234576)
10. Pan X, Arauz E, Krzanowski JJ, et al. Synergistic interactions between selective pharmacological inhibitors of phosphodiesterase isozyme families PDE III and PDE IV to attenuate proliferation of rat vascular smooth muscle cells. Biochem Pharmacol. 1994;48:827-835.
11. Ariga M, Neitzert B, Nakae S, et al. Nonredundant function of phosphodiesterases 4D and 4B in neutrophil recruitment to the site of inflammation. J Immunol. 2004;173:7531-7538. (Pubitemid 39628194)
12. Wang D, Deng C, Bugaj-Gaweda B, et al. Cloning and characterization of novel PDE4D isoforms PDE4D6 and PDE4D7. Cell Signal. 2003;15:883-891.
13. Bevan S, Porteous L, Sitzer M, et al. Phosphodiesterase 4D gene, ischemic stroke, and asymptomatic carotid atherosclerosis. Stroke. 2005;36:949-953.
14. Lohmussaar E, Gschwendtner A, Mueller JC, et al. ALOX5AP gene and the PDE4D gene in a central European population of stroke patients. Stroke. 2005;36:731-736. (Pubitemid 40490615)
15. Nilsson-Ardnor S, Wiklund PG, Lindgren P, et al. Linkage of ischemic stroke to the PDE4D region on 5q in a Swedish population. Stroke. 2005;36:1666-1671.
16. Saleheen D, Bukhari S, Haider SR, et al. Association of phosphodiesterase 4D gene with ischemic stroke in a Pakistani population. Stroke. 2005;36:2275-2277. (Pubitemid 41429259)
17. Meschia JF, Brott TG, Brown RD, Jr, et al. Phosphodiesterase 4D and 5-lipoxygenase activating protein in ischemic stroke. Ann Neurol. 2005;58:351-361.
18. Woo D, Kaushal R, Kissela B, et al. Association of Phosphodiesterase 4D with ischemic stroke: A population-based case-control study. Stroke. 2006;37:371-376.
19. Staton JM, Sayer MS, Hankey GJ, et al. Association between phosphodiesterase 4D gene and ischaemic stroke. J Neurol Neurosurg Psychiatry. 2006;77:1067-1069. (Pubitemid 44338532)
20. Kostulas K, Gretarsdottir S, Kostulas V, et al. PDE4D and ALOX5AP genetic variants and risk for ischemic cerebrovascular disease in Sweden. J Neurol Sci. 2007;263:113-117.
21. Brophy VH, Ro SK, Rhees BK, et al. Association of phosphodiesterase 4D polymorphisms with ischemic stroke in a U.S. population stratified by hypertension status. Stroke. 2006;37:1385-1390.
22. Nakayama T, Asai S, Sato N, et al. Genotype and haplotype association study of the STRK1 region on 5q12 among Japanese: A case-control study. Stroke. 2006;37:69-76.