Dietary fat-dependent transcriptional architecture and copy number alterations associated with modifiers of mammary cancer metastasis

Clinical and Experimental Metastasis

Volumn 27, Issue 5, 2010, Pages 279-293

  Gordon, Ryan R ^a,f   Merrill, Michele La ^d   Hunter, Kent W ^e   Sørensen, Peter ^g   Threadgill, David W ^b,c,f   Pomp, Daniel ^a,b,c  

^a University of North Carolina at Chapel Hill   (United States)

^b UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF NORTH CAROLINA   (United States)

^d MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^e NATIONAL CANCER INSTITUTE   (United States)

^f NORTH CAROLINA STATE UNIVERSITY   (United States)

^g AARHUS UNIVERSITY   (Denmark)

Author keywords

Breast cancer; Causality; eQTL; High fat diet; Tumors

Indexed keywords

DNA;

ARTICLE; BREAST CANCER; CANCER RISK; COPY NUMBER VARIATION; DNA MODIFICATION; FAT INTAKE; GENE EXPRESSION PROFILING; GENETIC ANALYSIS; GENETIC TRANSCRIPTION; HUMAN; METASTASIS; NUCLEOTIDE SEQUENCE; PATHOGENESIS; QUANTITATIVE TRAIT LOCUS; UNINDEXED SEQUENCE; ANIMAL; DRUG EFFECT; EPIDEMIOLOGY; EXPERIMENTAL NEOPLASM; GENE DOSAGE; GENETICS; MOUSE; PATHOLOGY; TRANSGENIC MOUSE;

ANIMALS; CAUSALITY; DIETARY FATS; GENE DOSAGE; MAMMARY NEOPLASMS, EXPERIMENTAL; MICE; MICE, TRANSGENIC; NEOPLASM METASTASIS; QUANTITATIVE TRAIT LOCI; TRANSCRIPTION, GENETIC;

EID: 77953934403     PISSN: 02620898     EISSN: 15737276     Source Type: Journal    
DOI: 10.1007/s10585-010-9326-z     Document Type: Article

References (32)

1. Rohan TE, Li SQ, Hartwick R, et al. (2006) p53 Alterations and protein accumulation in benign breast tissue and breast cancer risk: a cohort study. Cancer epidemiology, biomarkers & prevention: a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 15(7): 1316-1323 (Pubitemid 44125288)
2. CG Song Z Hu J Wu, et al. 2006 The prevalence of BRCA1 and BRCA2 mutations in eastern Chinese women with breast cancer J Cancer Res Clin Oncol 132 10 617 626 10.1007/s00432-006-0105-9 1:CAS:528:DC%2BD28XoslWmsbw%3D 16835750 (Pubitemid 44310327)
3. T Walsh S Casadei KH Coats, et al. 2006 Spectrum of mutations in BRCA1, BRCA2, CHEK2, and TP53 in families at high risk of breast cancer JAMA J Am Med Assoc 295 12 1379 1388 10.1001/jama.295.12.1379 1:CAS:528:DC%2BD28Xislehurs%3D
4. RR Gordon KW Hunter P Sorensen, et al. 2008 Genotype X diet interactions in mice predisposed to mammary cancer. I. Body weight and fat Mamm Genome 19 3 163 178 10.1007/s00335-008-9095-z 1:CAS:528:DC%2BD1cXjsF2gsb8%3D 18286334
5. MF Allan EJ Eisen D Pomp 2004 The M16 mouse: an outbred animal model of early onset polygenic obesity and diabesity Obes Res 12 9 1397 1407 10.1038/oby.2004.176 15483204 (Pubitemid 41137446)
6. CT Guy RD Cardiff WJ Muller 1992 Induction of mammary tumors by expression of polyomavirus middle T oncogene: a transgenic mouse model for metastatic disease Mol Cell Biol 12 3 954 961 1:CAS:528:DyaK38XhslWhtL8%3D 1312220
7. RR Gordon KW Hunter M La Merrill, et al. 2008 Genotype X diet interactions in mice predisposed to mammary cancer: II. Tumors and metastasis Mamm Genome 19 3 179 189 10.1007/s00335-008-9096-y 1:CAS:528: DC%2BD1cXjsF2gsLc%3D 18288525
8. M La Merrill RR Gordon KW Hunter, et al. 2010 Dietary fat alters pulmonary metastasis of mammary cancers through cancer autonomous and non-autonomous changes in gene expression Clin Exp Metastasis 27 2 107 116 10.1007/s10585-009-9302-7 1:CAS:528:DC%2BC3cXivFGntLw%3D 20151316
9. MF Allan EJ Eisen D Pomp 2005 Genomic mapping of direct and correlated responses to long-term selection for rapid growth rate in mice Genetics 170 4 1863 1877 10.1534/genetics.105.041319 1:CAS:528:DC%2BD2MXhtFeis7%2FM 15944354 (Pubitemid 41362838)
10. K Kuhn SC Baker E Chudin, et al. 2004 A novel, high-performance random array platform for quantitative gene expression profiling Genome Res 14 11 2347 2356 10.1101/gr.2739104 1:CAS:528:DC%2BD2cXpvVCiurY%3D 15520296 (Pubitemid 39517342)
11. P Du WA Kibbe SM Lin 2008 lumi: a pipeline for processing Illumina microarray Bioinformatics 24 13 1547 1548 10.1093/bioinformatics/btn224 1:CAS:528:DC%2BD1cXnvV2rtLg%3D 18467348 (Pubitemid 351911712)
12. VG Tusher R Tibshirani G Chu 2001 Significance analysis of microarrays applied to the ionizing radiation response Proc Natl Acad Sci U S A 98 9 5116 5121 10.1073/pnas.091062498 1:CAS:528:DC%2BD3MXjt1Ons7w%3D 11309499 (Pubitemid 32397092)
13. JD Storey 2002 A direct approach to false discovery rates J Roy Stat Soc Ser B 64 479 498 10.1111/1467-9868.00346
14. S Doss EE Schadt TA Drake, et al. 2005 Cis-acting expression quantitative trait loci in mice Genome Res 15 5 681 691 10.1101/gr.3216905 1:CAS:528:DC%2BD2MXkt1Clt7c%3D 15837804 (Pubitemid 41043638)
15. W Sun T Yu KC Li 2007 Detection of eQTL modules mediated by activity levels of transcription factors Bioinformatics 23 17 2290 2297 10.1093/bioinformatics/btm327 1:CAS:528:DC%2BD2sXhtVOrs7jJ 17599927 (Pubitemid 47423867)
16. DR Rhodes J Yu K Shanker, et al. 2004 ONCOMINE: a cancer microarray database and integrated data-mining platform Neoplasia 6 1 1 6 1:CAS:528:DC%2BD2cXjslSgtrY%3D 15068665 (Pubitemid 38391943)
17. NP Crawford X Qian A Ziogas, et al. 2007 Rrp1b, a new candidate susceptibility gene for breast cancer progression and metastasis PLoS Genet 3 11 e214 10.1371/journal.pgen.0030214 18081427 (Pubitemid 350291588)
18. EE Schadt J Lamb X Yang, et al. 2005 An integrative genomics approach to infer causal associations between gene expression and disease Nat Genet 37 7 710 717 10.1038/ng1589 1:CAS:528:DC%2BD2MXlslWhs7Y%3D 15965475 (Pubitemid 41754887)
19. SA Eccles G Box W Court, et al. 1994 Preclinical models for the evaluation of targeted therapies of metastatic disease Cell Biophys 24-25 279 291 7736534
20. NP Crawford RC Walker L Lukes, et al. 2008 The Diasporin Pathway: a tumor progression-related transcriptional network that predicts breast cancer survival Clin Exp Metastasis 25 4 357 369 10.1007/s10585-008-9146-6 1:CAS:528:DC%2BD1cXptVWjsr8%3D 18301994
21. S Yamashita K Wakazono T Nomoto, et al. 2005 Expression quantitative trait loci analysis of 13 genes in the rat prostate Genetics 171 3 1231 1238 10.1534/genetics.104.038174 1:CAS:528:DC%2BD28Xjs1KrtA%3D%3D 16079240 (Pubitemid 43234854)
22. SS Wang EE Schadt H Wang, et al. 2007 Identification of pathways for atherosclerosis in mice: integration of quantitative trait locus analysis and global gene expression data Circ Res 101 3 e11 e30 10.1161/CIRCRESAHA.107.152975 1:CAS:528:DC%2BD2sXotlahtrw%3D 17641228 (Pubitemid 47344081)
23. K Morgan A Uyuni G Nandgiri, et al. 2008 Altered expression of transcription factors and genes regulating lipogenesis in liver and adipose tissue of mice with high fat diet-induced obesity and nonalcoholic fatty liver disease Eur J Gastroenterol Hepatol 20 9 843 854 10.1097/MEG.0b013e3282f9b203 1:CAS:528:DC%2BD1cXhtVygtb%2FE 18794597
24. H Gong P Guo Y Zhai, et al. 2007 Estrogen deprivation and inhibition of breast cancer growth in vivo through activation of the orphan nuclear receptor liver X receptor Mol Endocrinol 21 8 1781 1790 10.1210/me.2007-0187 1:CAS:528:DC%2BD2sXos12ku7Y%3D 17536009 (Baltimore, Md) (Pubitemid 47173791)
25. MF Fraga E Ballestar A Villar-Garea, et al. 2005 Loss of acetylation at Lys16 and trimethylation at Lys20 of histone H4 is a common hallmark of human cancer Nat Genet 37 4 391 400 10.1038/ng1531 1:CAS:528:DC%2BD2MXislCmurg%3D 15765097 (Pubitemid 40490489)
26. DB Seligson S Horvath T Shi, et al. 2005 Global histone modification patterns predict risk of prostate cancer recurrence Nature 435 7046 1262 1266 10.1038/nature03672 1:CAS:528:DC%2BD2MXls1Ontbg%3D 15988529 (Pubitemid 40943093)
27. Y Liu M Tseng SA Perdreau, et al. 2007 Histone H2AX is a mediator of gastrointestinal stromal tumor cell apoptosis following treatment with imatinib mesylate Cancer Res 67 6 2685 2692 10.1158/0008-5472.CAN-06-3497 1:CAS:528:DC%2BD2sXivV2ns7k%3D 17363589 (Pubitemid 46548956)
28. HS Lee CB Park JM Kim, et al. 2008 Mechanism of anticancer activity of buforin IIb, a histone H2A-derived peptide Cancer Lett 271 1 47 55 10.1016/j.canlet.2008.05.041 1:CAS:528:DC%2BD1cXht1Sis7bP 18617323
29. NL Sieben J Oosting AM Flanagan, et al. 2005 Differential gene expression in ovarian tumors reveals Dusp 4 and Serpina 5 as key regulators for benign behavior of serous borderline tumors J Clin Oncol 23 29 7257 7264 10.1200/JCO.2005.02.2541 1:CAS:528:DC%2BD2MXhtF2nsL3I 16087957 (Pubitemid 46202340)
30. D Chitale Y Gong BS Taylor, et al. 2009 An integrated genomic analysis of lung cancer reveals loss of DUSP4 in EGFR-mutant tumors Oncogene 28 31 2773 2783 10.1038/onc.2009.135 1:CAS:528:DC%2BD1MXnt1Sht7c%3D 19525976
31. U Woelfle J Cloos G Sauter, et al. 2003 Molecular signature associated with bone marrow micrometastasis in human breast cancer Cancer Res 63 18 5679 5684 1:CAS:528:DC%2BD3sXnvVSjt7w%3D 14522883 (Pubitemid 37187461)
32. Rt Williams JE Lim B Harr, et al. 2009 A common and unstable copy number variant is associated with differences in Glo1 expression and anxiety-like behavior PLoS ONE 4 3 e4649 10.1371/journal.pone.0004649 19266052