Application of LC-NMR to the identification of bulk drug impurities in NK1 antagonist GW597599 (vestipitant)

Magnetic Resonance in Chemistry

Volumn 48, Issue 7, 2010, Pages 523-530

  Provera, Stefano ^a   Guercio, Giuseppe ^a   Turco, Lucilla ^a   Curcuruto, Ornella ^a   Alvaro, Giuseppe ^a   Rossi, Tino ^a   Marchioro, Carla ^a  

^a GSK   (Italy)

Author keywords

13C NMR; 15N NMR; 1HNMR; LC NMR; NK1 antagonists; Vestipitant

Indexed keywords

NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY;

13C NMR; 15N NMR; 1HNMR; BULK DRUGS; DRUG IMPURITIES; IMPURITIES IN; LIQUID CHROMATOGRAPHY-NMR; NK1 ANTAGONIST; NMR-SPECTROSCOPY; VESTIPITANT;

LIQUID CHROMATOGRAPHY;

FLUOROBENZENE; NEUROKININ 1 RECEPTOR ANTAGONIST; PIPERIDINE DERIVATIVE; SOLUTION AND SOLUBILITY; VESTIPITANT;

CHEMICAL STRUCTURE; CHEMISTRY; DRUG CONTAMINATION; DRUG INDUSTRY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PROCEDURES; SOLUTION AND SOLUBILITY; SYNTHESIS;

CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DRUG CONTAMINATION; DRUG INDUSTRY; FLUOROBENZENES; MAGNETIC RESONANCE SPECTROSCOPY; MASS SPECTROMETRY; MOLECULAR STRUCTURE; NEUROKININ-1 RECEPTOR ANTAGONISTS; PIPERIDINES; SOLUTIONS;

EID: 77953923807     PISSN: 07491581     EISSN: 1097458X     Source Type: Journal    
DOI: 10.1002/mrc.2611     Document Type: Article

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