Behavioral evaluation of adult rats exposed in utero to maternal epileptic seizures

Epilepsy and Behavior

Volumn 18, Issue 1-2, 2010, Pages 45-49

  Lima, Daiana Correia ^a   Gurgel do Vale, Tiago ^a   Arganãraz, Gustavo Adolfo ^a   Varella, Pedro Paulo Vasconcelos ^a   Frussa Filho, Roberto ^a   Cavalheiro, Esper Abrão ^a   Naffah Mazzacoratti, Maria da Graça ^a   Amado, Débora ^a  

^a FEDERAL UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Behavior; Hypoxia; Maternal seizures; Motor coordination deficits; Pilocarpine epilepsy model; Pregnancy

Indexed keywords

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANXIETY; ARTICLE; CONTROLLED STUDY; DEPRESSION; EPILEPSY; EXPOSURE; FEMALE; FETUS HYPOXIA; HISTOPATHOLOGY; IMMOBILIZATION; MALE; MOTOR COORDINATION; NONHUMAN; OPEN FIELD TEST; PLACENTA; PLACENTA INFARCTION; PREGNANCY; PROGENY; RAT; ROTAROD TEST; ANIMAL; CHEMICALLY INDUCED; MOTOR ACTIVITY; PATHOLOGY; PHYSIOLOGY; PRENATAL EXPOSURE; PSYCHOLOGY; SEIZURE; WISTAR RAT;

ANIMALS; ANXIETY; BEHAVIOR, ANIMAL; DEPRESSION; EPILEPSY; FEMALE; MALE; MOTOR ACTIVITY; PILOCARPINE; PLACENTA; PREGNANCY; PRENATAL EXPOSURE DELAYED EFFECTS; RATS; RATS, WISTAR; SEIZURES;

PILOCARPINE;

EID: 77953915637     PISSN: 15255050     EISSN: 15255069     Source Type: Journal    
DOI: 10.1016/j.yebeh.2010.02.024     Document Type: Article

References (25)

1. Amado D., Cavalheiro E.A. Hormonal and gestational parameters in female rats submitted to the pilocarpine model of epilepsy. Epilepsy Res 1998, 32:266-274.
2. Klein P., Van Passel-Clark L.M., Pezzullo J.C. Onset of epilepsy at the time of menarche. Neurology 2003, 60:495-497.
3. Herzog A.G. Reproductive endocrine considerations and hormonal therapy for women with epilepsy. Epilepsia 1991, 32:27-33.
4. Reghunath B. Neuroendocrine aspects of epilepsy and pregnancy. Proceedings of workshop on fertility and pregnancy among women with epilepsy. Trivandrum: Kerala Registry of Epilepsy and Pregnancy 1998, 7-11. S.V. Thomas (Ed.).
5. Calvert J.W., Zhang J.H. Pathophysiology of an hypoxic-ischemic insult during the perinatal period. Neurol Res 2005, 27:246-260.
6. Hossain M.A. Molecular mediators of hypoxic-ischemic injury and implications for epilepsy in the developing brain. Epilepsy Behav 2005, 7:204-213.
7. Towfighi J., Mauger D. Temporal evolution of neuronal changes in cerebral hypoxia-ischemia in developing rats: a quantitative light microscopic study. Brain Res Dev Brain Res 1998, 109:169-177.
8. Franck J.E., Roberts D.L. Combined kainate and ischemia produces 'mesial temporal sclerosis'. Neurosci Lett 1990, 118:159-163.
9. Wilhelm J., Morris D., Hotham N. Epilepsy and pregnancy: a review of 98 pregnancies. Aust NZ J Obstet Gynaecol 1990, 30:290-295.
10. Kingdom J.C., Kaufmann P. Oxygen and placental villous development: origins of fetal hypoxia. Placenta 1997, 18:613-621.
11. Cavalheiro E.A., Leite J.P., Bortolotto Z.A., Turski W.A., Ikonomida C., Turski L. Long-term effects of pilocarpine in rats: structural damage of the brain triggers kindling and spontaneous recurrent seizures. Epilepsia 1991, 32:778-782.
12. Council for International Organizations of Medical Services (CIOMS/OMS) Guiding principles for biomedical research involving animals 1985, World Health Organization, Geneva.
13. Cameron N.M., Champagne F.A., Parent C., Fish E.W., Ozaki-Kuroda K., Meaney M.J. The programming of individual differences in defensive responses and reproductive strategies in the rat through variations in maternal care. Neurosci Biobehav Rev 2005, 29:843-865.
14. Broadhurst P.L. The place of animal psychology in the development of psychosomatic research. Fortschr Psychosom Med 1960, 1:63-69.
15. Kuribara H., Higuchi Y., Tadokoro S. Effects of central depressants on rota-rod and traction performances in mice. Jpn J Pharmacol 1977, 27:117-126.
16. Porsolt R.D., Anton G., Blavet N., Jalfre M. Behavioural despair in rats: a new model sensitive to antidepressant treatments. Eur J Pharmacol 1978, 47:379-391.
17. Raffo E., Vasconcelos A.P., Boehrer A., Desor D., Nehlig A. Neurobehavioral maturation of offspring from epileptic dams: study in the rat lithium-pilocarpine model. Exp Neurol 2009, 219:414-423.
18. Szuran T., Zimmerman E., Pliska V., Pfister H.P., Welzl H. Prenatal stress effects on exploratory activity and stress-induced analgesia in rats. Dev Psychobiol 1991, 24:361-372.
19. Deminiere J.M., Piazza P.V., Guegan G., et al. Increased locomotor response to novelty and propensity to intravenous amphetamine self-administration in adult offspring of stressed mothers. Brain Res 1992, 586:135-139.
20. Gué M., Bravard A., Meunier J., et al. Sex differences in learning deficits induced by prenatal stress in juvenile rats. Behav Brain Res 2004, 150:149-157.
21. Vallée M., Mayo W., Dellu F., LE Moal M., Simon H., Maccari S. Prenatal stress induces high anxiety and postnatal handling induces low anxiety in adult offspring: correlation with stress-induced corticosterone secretion. J Neurosci 1997, 17:2626-2636.
22. Lehmann J., Stöhr T., Feldon J. Long-term effects of prenatal stress experience and postnatal maternal separation on emotionality and attentional processes. Behav Brain Res 2000, 107:133-144.
23. Rimondini R., Agren G., Börjesson S., Sommer W., Heilig M. Persistent behavioral and autonomic supersensitivity to stress following prenatal stress exposure in rats. Behav Brain Res 2003, 140:75-80.
24. Nishio H., Kasuga S., Ushimija M., Harada Y. Prenatal stress and postnatal development of neonatal rats: sex-dependent effects on emotional behavior and learning ability of neonatal rats. Int J Dev Neurosci 2001, 19:37-45.
25. West A.P. Neurobehavioral studies of forced swimming: the role of learning and memory in the forced swim test. Prog Neuropsychopharmacol Biol Psychiatry 1990, 14:863-877.