Investigation and comparison of colon specificity of novel polymer khaya gum with guar gum

Pakistan Journal of Pharmaceutical Sciences

Volumn 23, Issue 3, 2010, Pages 259-265

  Prabhu, Prabhakara ^a   Ahamed, Nissara ^a   Matapady, Harish Nairy ^a   Ahmed, Mohd Gulzar ^a   Narayanacharyulu, R ^a   Satyanarayana, D ^a   Subrahmanayam, Evs ^a  

^a NITTE DEEMED TO BE UNIVERSITY   (India)

Author keywords

Budesonide; Colon specific; Compression coated tablets; Guar gum; Khaya gum

Indexed keywords

BUDESONIDE; EUDRAGIT; GUAR GUM; KHAYA GUM; POLYMER; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; CECUM; COLON; COMPARATIVE STUDY; CONTROLLED STUDY; DRUG COATING; DRUG DEGRADATION; DRUG DELIVERY SYSTEM; DRUG QUALITY; DRUG RELEASE; DRUG SOLUBILITY; DRUG SPECIFICITY; ENTERIC COATED TABLET; MALE; MICROBIAL DEGRADATION; NONHUMAN; PHYSICAL CHEMISTRY; RABBIT; RAT; TABLET COMPRESSION; TABLET DISINTEGRATION; UPPER GASTROINTESTINAL TRACT;

ANIMALS; BUDESONIDE; COLON; DRUG CARRIERS; GALACTANS; HYDROGEN-ION CONCENTRATION; MALE; MANNANS; MELIACEAE; ORGAN SPECIFICITY; PLANT GUMS; POLYMERS; RABBITS; RATS; SOLUBILITY; TABLETS;

EID: 77953907287     PISSN: 1011601X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (11)

1. Al Saidan SM, Krishnaiah YSR, Satyanarayana V and Rao GS (2005). In vivo evaluation of guar gum based matrix tablets of rofecoxib for colonic drug delivery. Curr. Drug Del., 2(2): 155-163. (Pubitemid 40488625)
2. Ashford M, Fell JT (1994). Targeting drugs to colon; Delivery systems for oral administration. J. Drug Target., 2: 241-258. (Pubitemid 24310626)
3. Asqhar LF and Chandran S (2006). Multiparticulate formulation approach to colon specific drug delivery; Current prospective. J. Pharm. Pharm. Sci., 9(3): 327-338.
4. Higuchi T (1963). Mechanism of sustained action medication. Theoretical analysis of rate release of solid drugs dispersed in solid matrices. J. Pharm. Sci., 52: 1145-1149.
5. Maria FF, Erik U, Magdalena R, Silvia M, Bjorn M and Anders P (2005). Anti inflammatory effects of Budesonide in intestinal epithelial cells. Pharm. Res., 52(5): 420-428.
6. Nykanen P, Lempaa S, Aaltonen ML, Jurjenson H, Veski P and Marvola M (2001). Citric acid as excipient in multiple unit enteric coated tablets for targeting drugs on the colon. Int. J. Pharm., 229(1-2): 155-162.
7. Odeku OA and Itiola OA (2005). Evaluation of effects of khaya gum on the mechanical and release properties of paracetamol tablets. Drug Dev. Ind. Pharm., 29(3): 311-320.
8. Odeku OA and John TF (2005). In vitro evaluation of Khaya and Albizia gums as compression coatings for drug targeting to the colon. J. Pharm. Pharmcol., 57: 163-168.
9. Pharmacopoeia of India (1996). New Delhi: Ministry of Health and Family Welfare, Government of India, Controller of Publications, pp.735-736.
10. Purushotham KR, Prabhashankar B, Ashok K, Azeemuddin K, Biradar SS, Shrishail SP and Satyanath B (2003). Formulation and roentgenographic studies of naproxen-pectin based matrix tablets for colon. J. Biol. Med., 76: 149-154.
11. Yeole PG, Galgatte C, Babla CI and Nakhat PD (2006). Design and evaluation of xanthan gum based matrix tablets of diclofenac sodium. Indian J. Pharm. Sci., 68(2): 185-189