Antitumor activity of methylan polysaccharide derivatives

Biotechnology Letters

Volumn 32, Issue 7, 2010, Pages 891-895

  Ramachandran, Priyadharshini ^a   Jeya, Marimuthu ^a   Moon, Hee Jung ^a   Lee, Kyoung Mi ^a   Kim, In Won ^a   Kim, Jung Hoe ^b   Lee, Jung Kul ^a  

^a Konkuk University   (South Korea)

^b Korea Advanced Institute of Science and Technology (KAIST)   (South Korea)

Author keywords

Amination; Antitumor; Methylan; Polysaccharide

Indexed keywords

ANTI-TUMOR ACTIVITIES; ANTI-TUMORS; ANTITUMOR; CELL LINES; METHYLAN; QUATERNIZATION; REDUCTIVE AMINATION; TUMOR CELLS;

CELL CULTURE; CELL PROLIFERATION;

AMINES;

ANTINEOPLASTIC AGENT; POLYSACCHARIDE;

ARTICLE; CELL SURVIVAL; CHEMICAL STRUCTURE; CHEMISTRY; DRUG EFFECT; HUMAN; STRUCTURE ACTIVITY RELATION; SYNTHESIS; TUMOR CELL LINE;

ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; CELL SURVIVAL; HUMANS; MOLECULAR STRUCTURE; POLYSACCHARIDES; STRUCTURE-ACTIVITY RELATIONSHIP;

CITRUS MACROPHYLLA;

EID: 77953872427     PISSN: 01415492     EISSN: 15736776     Source Type: Journal    
DOI: 10.1007/s10529-010-0246-4     Document Type: Article

References (17)

1. Chihara G (1992) Immunopharmacology of Lentinan, a polysaccharide isolated from Lentinus edodes: its application as a host defence potentiator. Int J Orient Med 17: 57-77.
2. Chihara G, Hamuro J, Maeda Y et al (1970a) Fractionation and purification of polysaccharides with marked antitumour activity, especially Lentinan from Lentinus edodes (Bark) sing, an edible mushroom. Cancer Res 30: 2776-2781.
3. Chihara G, Hamuro J, Maeda YY et al (1970b) Antitumor polysaccharide derives chemically from natural glucan. Nature 225: 943-944.
4. Chihara G, Hamuro J, Maeda Y et al (1987) Antitumor and metastasis-inhibitory activities of lentinan as an immunomodulator: an overview. Cancer Detect Prev 1: 423-443.
5. Dong Y, Kwan CY, Chen ZN et al (1996) Antitumor effects of a refined polysaccharide peptide fraction isolated from Coriolus versicolor: in vitro and in vivo studies. Res Commun Mol Path Pharmacol 92: 140-148.
6. Hamuro J, Yamashita Y, Ohsaka Y et al (1971) Carboxymethylpachymaran, a new water soluble polysaccharide with marked antitumor activity. Nature 233: 486-487.
7. Huettemann E, Sakka SG (2005) Anaesthesia and anti-cancer chemotherapeutic drugs. Curr Opin Anaesthesiol 18: 307-314.
8. Lebeault JM, Kim JH, Choi JH (1991) Novel biological polymer. US patent no. 5, 064, 759.
9. Lee JK, Kim SY, Kim SU et al (2002) Synthesis of cationic polysaccharide derivatives and their hypocholesterolaemic capacity. Biotechnol Appl Biochem 35: 181-189.
10. Lee HM, Kim YJ, Kim HW et al (2006) Induction of apoptosis by Cordyceps militaris through activation of caspase-3 in leukemia HL-60 cells. Biol Pharm Bull 29(4): 670-674.
11. Nishimura L, Nishimura S, Nishi N et al (1984) Immunological activity of chitin and its derivatives. Vaccine 2: 93-99.
12. Oh DK, Kim SY, Kim JH (1996) Production of a polysaccharide, methylan, in Methylobacterium organophilum by controlling ammonium ion. Biotechnol Lett 18(12): 1427-1430.
13. Ooi VEC (2009) Antitumor and immunomodulatory activities of mushroom polysaccharides. In: Cheung PCK (ed) Mushrooms as functional foods. Wiley InterScience, New York.
14. Smith JE, Rowan NJ, Sullivan R (2002) Medicinal mushrooms: a rapidly developing area of biotechnology for cancer therapy and other bioactivities. Biotechnol Lett 24: 1839-1845.
15. Wasser SP (2002) Medicinal mushrooms as a source of antitumor and immunomodulating polysaccharides. Appl Microbiol Biotechnol 60: 258-274.
16. Yoshiba K, Teramoto A, Nakamura N et al (2003) Static water structure detected by heat capacity measurements on aqueous solutions of a triple-helical polysaccharide schizophyllan. Biomacromolecules 4(5): 1348-1356.
17. Zhu K, Henning D, Iwakuma T et al (1999) Adriamycin inhibits human RH II/Gu RNA helicase activity by binding to its substrate. Biochem Biophys Res Commun 266: 361-365.