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9
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77953870500
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note
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R 43.5 min).
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10
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77953873867
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note
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13C NMR, see Supplementary Tables S1 and S2.
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14
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85008438576
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Hattori M., Hada S., Kawata Y., Tezuka Y., Kikuchi T., and Namba T. Chem. Pharm. Bull. 35 (1987) 3315
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Namba, T.6
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16
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77953872611
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note
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5 cells/well in 2 mL growth medium. Differentiation of C2C12 myoblasts was induced by replacing the growth medium with DMEM containing 5% horse serum when the cells reached confluence. The medium was changed every 48 h until the formation of myotubes was observed. The cells were used in the experiments at 4-5 days after differentiation.
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17
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33749336146
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note
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79. β-Actin protein levels were used as a control for equal protein loading. The immunoreactive antigen was then recognized using a horseradish peroxidase-labeled anti-rabbit IgG and an enhanced chemiluminescence detection kit (Lee, Y. S.; Kim, W. S.; Kim, K. H.; Yoon, M. J.; Cho, H. J.; Shen, Y.; Ye, J. M.; Lee, C. H.; Oh, W. K.; Kim, C. T.; Cordula, H. B.; Gosby, A.; Kraegen, E. W.; James, D. E.; Kim, J. B. Diabetes 2006, 55, 2256).
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18
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77953871501
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Animal experiments: Thirty eight-week-old male C57BL/6 mice were housed in plastic cages in a temperature-controlled (22 ± 1 °C) room and maintained on a reverse 12 h light/dark cycle. The mice were divided randomly into three groups: normal diet group (ND), high-fat diet group (HFD) with a daily gavage of the vehicle as control; and HFD + 200 mg/kg of tetrahydrofuran mixture-fed group (HFD + THF). The HFD (DIO series diets, Research Diets Inc., USA) was based on a modified Western diet and contained 21% (w/w) lard and 0.15% (w/w) cholesterol (Moon, H. S.; Lee, H. G.; Seo, J. H.; Chung, C. S.; Kim, T. G.; Choi, Y. J.; Cho, C. S. J. Nutr. Biochem. 2009, 20, 187). The tetrahydrofuran mixture was administered for 6 weeks, and the weight gain was measured every week. The food intake was measured for three consecutive days per week by subtracting the food jar pre- and post-weights for 6 weeks, and the mean values were used as the daily food intake. At the necropsy, both sides of the inguinal and epididymal adipose tissues were removed and weighed, and the relative adipose tissue weight to body weight was calculated. All animal experiments were approved by the Institutional Animal Care and Use Committee, and were performed in accordance with the institutional guidelines at AmorePacific Corporation, Korea.
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19
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77049092274
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Nor J.R., Kim Y.H., Gang G.T., Yang K.J., Lee H.S., Nguyen P.H., Oh W.K., Song K.S., and Lee C.H. Food Chem. 121 (2010) 437
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Oh, W.K.7
Song, K.S.8
Lee, C.H.9
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20
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13444265891
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Oh, W.1
Abu-Elheiga, L.2
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Gu, Z.4
Shaikenov, T.5
Chirala, S.S.6
Wakil, S.J.7
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