Effect of water soluble carriers on dissolution enhancement of aceclofenac

Asian Journal of Pharmaceutics

Volumn 4, Issue 1, 2010, Pages 34-40

  Dahiya, Sunita ^a   Kaushik, Atul ^b  

^a NRI Institute of Pharmacy   (India)

^b Institute of Professional Studies   (India)

Author keywords

Aceclofenac; BCS class II; dissolution enhancement; poorly water soluble drug; solid dispersion; water soluble carrier

Indexed keywords

ACECLOFENAC; BETA CYCLODEXTRIN; LACTOSE; MACROGOL 6000; MAGNESIUM STEARATE; STARCH; STARCH GLYCOLATE SODIUM; TALC; WATER;

ARTICLE; CONTROLLED STUDY; DIFFERENTIAL SCANNING CALORIMETRY; DRUG RELEASE; DRUG SOLUBILITY; DRUG STABILITY; EVAPORATION; IN VITRO STUDY; SCANNING ELECTRON MICROSCOPY; SOLID STATE; TABLET COMPRESSION; TABLET FRIABILITY; TABLET HARDNESS; TABLET THICKNESS;

EID: 77953825856     PISSN: 09738398     EISSN: 1998409X     Source Type: Journal    
DOI: 10.4103/0973-8398.63984     Document Type: Article

References (18)

1. Sweetman SC. Martindale: the complete drug reference. Great Britain: The Pharmaceutical Press; 2002. p. 11.
2. Suhagia BN, Patel HM, Shah SA, Rathod I, Parmar VK. Preparation and characterization of etoricoxib-polyethylene glycol 4000 plus polyvinylpyrrolidone K30 solid dispersions. Acta Pharm 2006;56:285-298
3. Serajuddin AT. Solid dispersion of poorly water soluble drugs: early promises, susbsequent problems, and recent breakthroughs. J Pharm Sci 1999;88:1058-1066
4. Serajuddin AT, Sheen PC, Augustine MA. Improved dissolution of a poorly water-soluble drug from solid dispersions in polyethylene glycol: polysorbate 80 mixtures. J Pharm Sci 1990;79:463-464
5. Betageri GV, Makarla KR. Enhancement of dissolution of glyburide by solid dispersion and lyophilization techniques. Int J Pharm 1995;126:155-160
6. Higuchi T, Connors KA. Phase solubility techniques. In: Reilly CN, editor. Advances in analytical chemistry instrumentation. New York: Interscience; 1965. p. 117-212.
7. Chutimaworapan S, Ritthidej GC, Yonemochi E, Oguchi T, Yamamoto K. Effect of water soluble carriers on dissolution characteristics of nifedipine solid dispersions. Drug Dev Ind Pharm 2000;26:1141-1150
8. Fernandez M, Rodriguez IC, Margarit MV, Cerezo A. Characterization of solid dispersions of piroxicam/poly(ethylene glycol) 4000. Int J Pharm 1992;84:197-202.
9. United States Pharmacopoeia 27, NF 18. Rockville: The USP Convention 1995. p. 2303-2304
10. Peck GE, Baley GJ, Mc Curdy VE, Banker GS. Tablet formulation and design. In: Lieberman HA, Lachman L, Schwartz B. Pharmaceutical Dosage Forms: Tablets Vol1, 2nd ed. revised and expanded. New York: Marcel Dekker Inc; 1989. p. 109.
11. Christoher R, Eleftheria N. Analysis of dissolution data. In: Dressman, JB, Lennernas H, editors. Oral Drug Absortion: prediction and Assessment. New York: Marcel Dekker Inc; 2000. p. 241-242
12. Kulkarni GT, Gowthamraja K, Suresh B. Stability testing of pharmaceutical products: an overview. Ind J Pharm Edu 2004;38:194-202.
13. Ozdemir N, Ordu S. Improvement of dissolution properties of furosemide by complexation with beta-cyclodextrin. Drug Dev Ind Pharm 1998;24:19-25.
14. Guidance for industry: Dissolution testing of Immediate Release Solid Dosage forms, United States Department of Health and Human Services, Food and Drug Administration, Center for Drug Evaluation and Research (CDER) 1997. p. 1-17.
15. Leuner C, Dressman J. Improving drug solubility for oral delivery using solid dispersions. Eur J Pharm Biopharm 2000;50:47-60.
16. Craig DQ. The mechanism of solid dispersions in water soluble polymers. Int J Pharm 2002;231:131-144
17. Khan KA. The concept of dissolution efficiency. J Pharm Pharmacol 1975:27:48-49
18. Costa P, Lobo JMS. Modeling and comparison of dissolution profiles. Eur J Pharm Sci 2001;13:123-133