Cationic copolymers nanoparticles for nonviral gene vectors: Synthesis, characterization, and application in gene delivery

Journal of Biomedical Materials Research - Part A

Volumn 94, Issue 2, 2010, Pages 619-630

  D'Ayala, Giovanna Gomez ^a   Calarco, Anna ^b   Malinconico, Mario ^a   Laurienzo, Paola ^a   Petillo, Orsolina ^b   Torpedine, Angela ^b   Peluso, Gianfranco ^b  

^a CNR   (Italy)

^b INSTITUTE OF PROTEIN BIOCHEMISTRY   (Italy)

Author keywords

Gene delivery; Nanoparticles; Nonviral DNA vectors; Poly(ethylenimine); Polycaprolactone

Indexed keywords

CONJUGATED POLYMERS; CROSSLINKING; DNA; GENE THERAPY; GENE TRANSFER; NANOPARTICLES; NUCLEIC ACIDS; POLYCAPROLACTONE; POLYMER BLENDS; POLYMERS; TOXICITY;

BIOCOMPATIBLE POLYMER; BIODEGRADABLE ALIPHATIC POLYESTERS; BIOLOGICAL EFFECTS; BIOLOGICAL PROPERTIES; CAPROLACTONE; CATIONIC COPOLYMER; CELL TOXICITY; CROSSLINKED; DELIVERY SYSTEMS; DNA BINDING; DNA VECTORS; GENE DELIVERY; GENE VECTORS; HIGH MOLECULAR WEIGHT; IN-VIVO; LOW TOXICITY; NANO-SIZED PARTICLES; NONIONIC; NONVIRAL; POLY(ETHYLENIMINE); POLYCATIONS; POLYETHYLENIMINES; POLYMERIC NANOPARTICLES; SOLUBLE AGGREGATES; TOXIC EFFECT; TRANSFECTION AGENTS; TRANSFECTION EFFICIENCY;

GENE EXPRESSION;

COPOLYMER; DEOXYRIBONUCLEASE I; NANOPARTICLE; PLASMID DNA; POLYCAPROLACTONE; POLYETHYLENEIMINE; CATION; DNA; POLYESTER;

ARTICLE; CELL VIABILITY; CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; CROSS LINKING; CYTOTOXICITY; DNA BINDING; DNA VECTOR; GENE EXPRESSION; HUMAN; HUMAN CELL; NONVIRAL GENE DELIVERY SYSTEM; PARTICLE SIZE; SCANNING ELECTRON MICROSCOPE; TENSILE STRENGTH; YOUNG MODULUS; ZETA POTENTIAL; CHEMICAL STRUCTURE; CHEMISTRY; DIFFERENTIAL SCANNING CALORIMETRY; GENE THERAPY; GENE TRANSFER; GENE VECTOR; GENETIC TRANSFECTION; GENETICS; MATERIALS TESTING; METABOLISM; MOLECULAR WEIGHT; SYNTHESIS; TUMOR CELL LINE;

CALORIMETRY, DIFFERENTIAL SCANNING; CATIONS; CELL LINE, TUMOR; DNA; GENE TRANSFER TECHNIQUES; GENETIC THERAPY; GENETIC VECTORS; HUMANS; MATERIALS TESTING; MOLECULAR STRUCTURE; MOLECULAR WEIGHT; NANOPARTICLES; PARTICLE SIZE; POLYESTERS; POLYETHYLENEIMINE; TENSILE STRENGTH; TRANSFECTION;

EID: 77953825608     PISSN: 15493296     EISSN: 15524965     Source Type: Journal    
DOI: 10.1002/jbm.a.32752     Document Type: Article

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