Loading of plasmid DNA into PLGA microparticles using TROMS (Total Recirculation One-Machine System): Evaluation of its integrity and controlled release properties

Journal of Controlled Release

Volumn 86, Issue 1, 2003, Pages 123-130

  Garcia del Barrio G ^a   Novo, F J ^a   Irache, J M ^a  

^a UNIVERSITY OF NAVARRA   (Spain)

Author keywords

Plasmid DNA, muscle gene transfer; PLGA microparticles, controlled release; TROMS (Total Recirculation One Machine System)

Indexed keywords

NAKED DNA; PLASMID DNA; POLOXAMER; POLYESTER; POLYGLACTIN; POVIDONE; RESOMER; DNA; LACTIC ACID; MICROSPHERE; POLYGLYCOLIC ACID; POLYLACTIC ACID POLYGLYCOLIC ACID COPOLYMER; POLYLACTIC ACID-POLYGLYCOLIC ACID COPOLYMER; POLYMER;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED DRUG RELEASE; CONTROLLED STUDY; DRUG FORMULATION; DRUG SCREENING; DRUG SYNTHESIS; FEMALE; FLUOROMETRY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; RAT; SKELETAL MUSCLE; ANIMAL; COMPARATIVE STUDY; DELAYED RELEASE FORMULATION; GENETIC TRANSFECTION; INSTRUMENTATION; METHODOLOGY; PHARMACEUTICS; PLASMID; SYNTHESIS; WISTAR RAT;

ANIMALS; DELAYED-ACTION PREPARATIONS; DNA; FEMALE; LACTIC ACID; MICROSPHERES; PLASMIDS; POLYGLYCOLIC ACID; POLYMERS; RATS; RATS, WISTAR; TECHNOLOGY, PHARMACEUTICAL; TRANSFECTION;

EID: 1842655961     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-3659(02)00371-1     Document Type: Article

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