메뉴 건너뛰기




Volumn 32, Issue 7, 2010, Pages 883-890

PEGylation of alpha-momorcharin: Synthesis and characterization of novel anti-tumor conjugates with therapeutic potential

Author keywords

Acute toxicity; Alpha momorcharin; Anti tumor activity; Immunogenicity; PEGylation

Indexed keywords

ACUTE TOXICITY; ANTI-TUMOR ACTIVITIES; ANTI-TUMOR AGENTS; ANTI-TUMORS; CLINICAL APPLICATION; IMMUNOGENICITY; IN-VITRO; PEGYLATION; POTENTIAL APPLICATIONS; RIBOSOME-INACTIVATING PROTEIN; SYNTHESIS AND CHARACTERIZATION; THERAPEUTIC POTENTIALS; TUMOR CELLS;

EID: 77953821992     PISSN: 01415492     EISSN: 15736776     Source Type: Journal    
DOI: 10.1007/s10529-010-0242-8     Document Type: Article
Times cited : (38)

References (15)
  • 1
    • 0034646833 scopus 로고    scopus 로고
    • The plant ribosome inactivating proteins luffin and saporin are potent inhibitors of HIV-1 integrase
    • Au TK, Collins RA, Lam TL et al (2000) The plant ribosome inactivating proteins luffin and saporin are potent inhibitors of HIV-1 integrase. FEBS Lett 471: 169-172.
    • (2000) FEBS Lett , vol.471 , pp. 169-172
    • Au, T.K.1    Collins, R.A.2    Lam, T.L.3
  • 2
    • 0032211606 scopus 로고    scopus 로고
    • Polyethylene glycol-conjugated pharmaceutical proteins
    • Bailon P, Berthold W (1998) Polyethylene glycol-conjugated pharmaceutical proteins. Pharm Sci Tech Today 1: 352-356.
    • (1998) Pharm Sci Tech Today , vol.1 , pp. 352-356
    • Bailon, P.1    Berthold, W.2
  • 3
    • 0344420226 scopus 로고    scopus 로고
    • Pharmacokinetic and biodistribution properties of poly (ethylene glycol)-protein conjugates
    • Caliceti P, Veronese FM (2003) Pharmacokinetic and biodistribution properties of poly (ethylene glycol)-protein conjugates. Adv Drug Deliv Rev 55: 1261-1277.
    • (2003) Adv Drug Deliv Rev , vol.55 , pp. 1261-1277
    • Caliceti, P.1    Veronese, F.M.2
  • 4
    • 0026644567 scopus 로고
    • Deoxyribonucleolytic activity of alpha-momorcharin and beta-momorcharin
    • Go TTM, Yeung HW, Fong WP (1992) Deoxyribonucleolytic activity of alpha-momorcharin and beta-momorcharin. Life Sci 51: 1347-1353.
    • (1992) Life Sci , vol.51 , pp. 1347-1353
    • Go, T.T.M.1    Yeung, H.W.2    Fong, W.P.3
  • 5
    • 57249103219 scopus 로고    scopus 로고
    • Comparative plasma membrane-associated proteomics of immortalized human hepatocytes
    • Gou LT, Tong AP, Chen LJ et al (2008) Comparative plasma membrane-associated proteomics of immortalized human hepatocytes. Biochem (Moscow) 73: 1200-1206.
    • (2008) Biochem (Moscow) , vol.73 , pp. 1200-1206
    • Gou, L.T.1    Tong, A.P.2    Chen, L.J.3
  • 6
    • 2942538292 scopus 로고    scopus 로고
    • Pharmacological actions and potential uses of Momordica charantia: A review
    • Grover JK, Yadav SP (2004) Pharmacological actions and potential uses of Momordica charantia: a review. J Ethnopharmacol 93: 123-132.
    • (2004) J Ethnopharmacol , vol.93 , pp. 123-132
    • Grover, J.K.1    Yadav, S.P.2
  • 7
    • 0023181362 scopus 로고
    • The immunosuppressive activities of 2 abortifacient proteins isolated from the seeds of bitter-melon (Momordica charantia)
    • Leung SO, Yeung HW, Leung KN (1987) The immunosuppressive activities of 2 abortifacient proteins isolated from the seeds of bitter-melon (Momordica charantia). Immunopharmacology 13: 159-171.
    • (1987) Immunopharmacology , vol.13 , pp. 159-171
    • Leung, S.O.1    Yeung, H.W.2    Leung, K.N.3
  • 8
    • 73349117183 scopus 로고    scopus 로고
    • Anti-tumor activity and immunological modification of ribosome-inactivating protein (RIP) from Momordica charantia by covalent attachment of polyethylene glycol
    • Li ME, Chen YW, Liu ZY et al (2009) Anti-tumor activity and immunological modification of ribosome-inactivating protein (RIP) from Momordica charantia by covalent attachment of polyethylene glycol. Acta Biochim Biophy Sin 41: 782-799.
    • (2009) Acta Biochim Biophy Sin , vol.41 , pp. 782-799
    • Li, M.E.1    Chen, Y.W.2    Liu, Z.Y.3
  • 9
    • 0030601742 scopus 로고    scopus 로고
    • Demonstration of ribonuclease activity in the plant ribosome-inactivating proteins alpha- and beta-momorchrins
    • Mock JWY, Ng TB, Wong RNS et al (1996) Demonstration of ribonuclease activity in the plant ribosome-inactivating proteins alpha- and beta-momorchrins. Life Sci 59: 1853-1859.
    • (1996) Life Sci , vol.59 , pp. 1853-1859
    • Mock, J.W.Y.1    Ng, T.B.2    Wong, R.N.S.3
  • 10
    • 0028176506 scopus 로고
    • Action of α-momorcharin, a ribosome inactivating protein, on cultured tumor cell lines
    • Ng TB, Liu WK, Sze SF et al (1994) Action of α-momorcharin, a ribosome inactivating protein, on cultured tumor cell lines. Gen Pharmacol 25: 75-77.
    • (1994) Gen Pharmacol , vol.25 , pp. 75-77
    • Ng, T.B.1    Liu, W.K.2    Sze, S.F.3
  • 11
    • 0028177695 scopus 로고
    • The N-glycosidase mechanism of ribosome-inactivating proteins implied by crystal structures of α-momorcharin
    • Ren JS, Wang YP, Dong YC et al (1994) The N-glycosidase mechanism of ribosome-inactivating proteins implied by crystal structures of α-momorcharin. Structure 2: 7-16.
    • (1994) Structure , vol.2 , pp. 7-16
    • Ren, J.S.1    Wang, Y.P.2    Dong, Y.C.3
  • 12
    • 33747229123 scopus 로고    scopus 로고
    • Ribosome-inactivating proteins: Progress and problems Cell
    • Stirpe F, Battelli MG (2006) Ribosome-inactivating proteins: progress and problems Cell. Mol Life Sci 63: 1850-1866.
    • (2006) Mol Life Sci , vol.63 , pp. 1850-1866
    • Stirpe, F.1    Battelli, M.G.2
  • 13
    • 0021246110 scopus 로고
    • Viability of alpha-momorcharin-treated mouse blastocysts in the pseudopregnant uterus
    • Tam PP, Chan WY, Yeung HW (1984) Viability of alpha-momorcharin-treated mouse blastocysts in the pseudopregnant uterus. J Reprod Fertil 72: 567-572.
    • (1984) J Reprod Fertil , vol.72 , pp. 567-572
    • Tam, P.P.1    Chan, W.Y.2    Yeung, H.W.3
  • 14
    • 0035284411 scopus 로고    scopus 로고
    • Peptide and protein PEGylation:A review of problems and solutions
    • Veronese FM (2001) Peptide and protein PEGylation: a review of problems and solutions. Biomaterials 22: 405-417.
    • (2001) Biomaterials , vol.22 , pp. 405-417
    • Veronese, F.M.1
  • 15
    • 26944452043 scopus 로고    scopus 로고
    • PEGylation, successful approach to drug deliver
    • Veronese FM, Pasut G (2005) PEGylation, successful approach to drug deliver. Drug Discov Today 10: 1451-1458.
    • (2005) Drug Discov Today , vol.10 , pp. 1451-1458
    • Veronese, F.M.1    Pasut, G.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.