Donor P-gp polymorphisms strongly influence renal function and graft loss in a cohort of renal transplant recipients on cyclosporine therapy in a long-term follow-up

Clinical Pharmacology and Therapeutics

Volumn 88, Issue 1, 2010, Pages 95-100

  Woillard, J B ^a,b   Rerolle, J P ^a,c   Picard, N ^a,b,c   Rousseau, A ^a,b   Guillaudeau, A ^c   Munteanu, E ^c   Essig, M ^a,c   Drouet, M ^c   Le Meur, Y ^a,d   Marquet, P ^a,b,c  

^a Univ Limoges   (France)

^b UNIVERSITY OF LIMOGES   (France)

^c DUPUYTREN UNIVERSITY HOSPITAL   (France)

^d SERVICE DE RHUMATOLOGIE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOSPORIN A; CYTOCHROME P450 3A4; CYTOCHROME P450 3A5; GLYCOPROTEIN P; MULTIDRUG RESISTANCE PROTEIN 1;

ADULT; AGED; ARTICLE; FEMALE; FOLLOW UP; GENE FREQUENCY; GENETIC POLYMORPHISM; GENOTYPE; GRAFT FAILURE; GRAFT RECIPIENT; HAPLOTYPE; HUMAN; IMMUNOSUPPRESSIVE TREATMENT; KAPLAN MEIER METHOD; KIDNEY DONOR; KIDNEY GRAFT REJECTION; MAJOR CLINICAL STUDY; MALE; MULTIVARIATE ANALYSIS; PRIORITY JOURNAL; RISK FACTOR;

ADULT; AGED; ANALYSIS OF VARIANCE; COHORT STUDIES; CYCLOSPORINE; CYTOCHROME P-450 CYP3A; FEMALE; FOLLOW-UP STUDIES; GENOTYPE; GRAFT REJECTION; HAPLOTYPES; HUMANS; IMMUNOSUPPRESSIVE AGENTS; KAPLAN-MEIERS ESTIMATE; KIDNEY; KIDNEY FUNCTION TESTS; KIDNEY TRANSPLANTATION; MALE; MIDDLE AGED; P-GLYCOPROTEIN; POLYMORPHISM, GENETIC; RETROSPECTIVE STUDIES; RISK FACTORS; TISSUE DONORS; YOUNG ADULT;

EID: 77953809847     PISSN: 00099236     EISSN: 15326535     Source Type: Journal    
DOI: 10.1038/clpt.2010.62     Document Type: Article

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