Comparison of the Safety and Efficacy of Cyclosporine Minimization Versus Cyclosporine Elimination in De Novo Renal Allograft Patients Receiving Sirolimus
Efficacy of sirolimus compared with azathioprine for reduction of acute renal allograft rejection: a randomised multicentre study
Rapamune US Study Group
Kahan B.D., and Rapamune US Study Group. Efficacy of sirolimus compared with azathioprine for reduction of acute renal allograft rejection: a randomised multicentre study. Lancet 356 (2000) 194
A worldwide, phase III, randomized, controlled, safety and efficacy study of a sirolimus/cyclosporine regimen for prevention of acute rejection in recipients of primary mismatched renal allografts
Rapamune Global Study Group
MacDonald A.S., and Rapamune Global Study Group. A worldwide, phase III, randomized, controlled, safety and efficacy study of a sirolimus/cyclosporine regimen for prevention of acute rejection in recipients of primary mismatched renal allografts. Transplantation 71 (2001) 271
Improved renal function in sirolimus-treated renal transplant patients after early cyclosporine elimination
Sirolimus Renal Function Study Group
Gonwa T.A., Hricik D.E., Brinker K., et al., Sirolimus Renal Function Study Group. Improved renal function in sirolimus-treated renal transplant patients after early cyclosporine elimination. Transplantation 74 (2002) 1560
Sirolimus allows early cyclosporine withdrawal in renal transplantation resulting in improved renal function and lower blood pressure
Johnson R.W., Kreis H., Oberbauer R., et al. Sirolimus allows early cyclosporine withdrawal in renal transplantation resulting in improved renal function and lower blood pressure. Transplantation 72 (2001) 777
Long-term benefits with sirolimus-based therapy after early cyclosporine withdrawal
Kreis H., Oberbauer R., Campistol J.M., et al. Long-term benefits with sirolimus-based therapy after early cyclosporine withdrawal. J Am Soc Nephrol 15 (2004) 809
Long-term improvement in renal function with sirolimus after early cyclosporine withdrawal in renal transplant recipients: 2-year results of the Rapamune Maintenance Regimen Study
Oberbauer R., Kreis H., Johnson R.W., et al. Long-term improvement in renal function with sirolimus after early cyclosporine withdrawal in renal transplant recipients: 2-year results of the Rapamune Maintenance Regimen Study. Transplantation 76 (2003) 364
Early cyclosporine withdrawal from a sirolimus-based regimen results in better renal allograft survival and renal function at 48 months after transplantation
Oberbauer R., Segoloni G., Campistol J.M., et al. Early cyclosporine withdrawal from a sirolimus-based regimen results in better renal allograft survival and renal function at 48 months after transplantation. Transpl Int 18 (2005) 22
A phase III prospective, randomized study to evaluate concentration-controlled sirolimus (rapamune) with cyclosporine dose minimization or elimination at six months in de novo renal allograft recipients
Baboolal K. A phase III prospective, randomized study to evaluate concentration-controlled sirolimus (rapamune) with cyclosporine dose minimization or elimination at six months in de novo renal allograft recipients. Transplantation 75 (2003) 1404
The place of sirolimus in kidney transplantation: can we reduce calcineurin inhibitor renal toxicity?
Knight R.J., and Kahan B.D. The place of sirolimus in kidney transplantation: can we reduce calcineurin inhibitor renal toxicity?. Kidney Int 70 (2006) 994
Early sirolimus use with cyclosporine elimination does not induce progressive proteinuria
Ruiz J.C., Campistol J.M., Sanchez-Fructuoso A., et al. Early sirolimus use with cyclosporine elimination does not induce progressive proteinuria. Transplant Proc 39 (2007) 2151