Disease onset in familial and sporadic primary progressive multiple sclerosis

Multiple Sclerosis

Volumn 16, Issue 6, 2010, Pages 694-700

  Koch, M ^a,b   Zhao, Y ^a   Yee, I ^a   Guimond, C ^a   Kingwell, E ^a   Rieckmann, P ^a   Sadovnick, D ^a   Tremlett, H ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^b UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

Author keywords

Familial MS; Genetics; Multiple sclerosis; Primary progressive MS; Risk factors

Indexed keywords

ADULT; ARTICLE; DATA BASE; DISEASE COURSE; DNA MODIFICATION; EARLY DIAGNOSIS; FAMILIAL DISEASE; FEMALE; HUMAN; LONGITUDINAL STUDY; MAJOR CLINICAL STUDY; MALE; MULTIPLE SCLEROSIS; ONSET AGE; POPULATION BASED CASE CONTROL STUDY; PRIMARY PROGRESSIVE MULTIPLE SCLEROSIS; RISK FACTOR; SEX RATIO; FACTUAL DATABASE; GENETICS; MULTIPLE SCLEROSIS, CHRONIC PROGRESSIVE; NONPARAMETRIC TEST; SEX DIFFERENCE;

AGE OF ONSET; DATABASES, FACTUAL; DISEASE PROGRESSION; FEMALE; HUMANS; LONGITUDINAL STUDIES; MALE; MULTIPLE SCLEROSIS, CHRONIC PROGRESSIVE; RISK FACTORS; SEX FACTORS; STATISTICS, NONPARAMETRIC;

EID: 77953774392     PISSN: 13524585     EISSN: None     Source Type: Journal    
DOI: 10.1177/1352458510367661     Document Type: Article

References (19)

1. Miller DH, Leary SM Primary-progressive multiple sclerosis. Lancet Neurol 2007 ; 6: 903-912.
2. Tremlett H., Paty D., Devonshire V. The natural history of primary progressive MS in British Columbia, Canada. Neurology 2005 ; 65: 1919-1923.
3. Kutzelnigg A., Lucchinetti CF, Stadelmann C., et al. Cortical demyelination and diffuse white matter injury in multiple sclerosis. Brain 2005 ; 128: 2705-2712.
4. Bjartmar C., Trapp BD Axonal degeneration and progressive neurologic disability in multiple sclerosis. Neurotox Res 2003 ; 5: 157-164.
5. Lassmann H. Axonal injury in multiple sclerosis. J Neurol Neurosurg Psychiatry 2003 ; 74: 695-697.
6. Koch M., Uyttenboogaart M., Heerings M., et al. Progression in familial and nonfamilial MS. Mult Scler 2008 ; 14: 300-306.
7. Sadovnick AD, Ebers GC, Wilson RW, et al. Life expectancy in patients attending multiple sclerosis clinics. Neurology 1992 ; 42: 991-994.
8. Sweeney VP, Sadovnick AD, Brandejs V. Prevalence of multiple sclerosis in British Columbia. Can J Neurol Sci 1986 ; 13: 47-51.
9. Poser CM, Paty DW, Scheinberg L., et al. New diagnostic criteria for multiple sclerosis: guidelines for research protocols. Ann Neurol 1983 ; 13: 227-231.
10. Lublin FD, Reingold SC Defining the clinical course of multiple sclerosis: results of an international survey. National Multiple Sclerosis Society (USA) Advisory Committee on Clinical Trials of New Agents in Multiple Sclerosis. Neurology 1996 ; 46: 907-911.
11. Confavreux C., Vukusic S. Natural history of multiple sclerosis: a unifying concept. Brain 2006 ; 129: 606-616. (Pubitemid 43278223)
12. Cottrell DA, Kremenchutzky M., Rice GP, et al. The natural history of multiple sclerosis: a geographically based study. 5. The clinical features and natural history of primary progressive multiple sclerosis. Brain 1999 ; 122: 625-639. (Pubitemid 29158771)
13. Koch M., Mostert J., Heersema D., et al. Progression in multiple sclerosis: further evidence of an age dependent process. J Neurol Sci 2007 ; 255: 35-41.
14. Ebers GC, Koopman WJ, Hader W., et al. The natural history of multiple sclerosis: a geographically based study: 8: familial multiple sclerosis. Brain 2000 ; 123: 641-649.
15. Weinshenker BG, Bulman D., Carriere W., et al. A comparison of sporadic and familial multiple sclerosis. Neurology 1990 ; 40: 1354-1358.
16. Ramagopalan SV, Valdar W., Dyment DA, et al. Association of infectious mononucleosis with multiple sclerosis. A population-based study. Neuroepidemiol 2009 ; 32: 257-262.
17. Bertram L., Tanzi RE The genetic epidemiology of neurodegenerative disease. J Clin Invest 2005 ; 115: 1449-1457.
18. Sawcer S. The complex genetics of multiple sclerosis: pitfalls and prospects. Brain 2008 ; 131: 3118-3131.
19. Ramagopalan SV, Deluca GC, Degenhardt A., et al. The genetics of clinical outcome in multiple sclerosis. J Neuroimmunol 2008 ; 201-202: 183-199.