A GPIb-IX-V complex signaling environment

Journal of Thrombosis and Haemostasis

Volumn 8, Issue 5, 2010, Pages 1075-1076

  Gardiner, E E ^a  

^a MONASH UNIVERSITY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGEN; CYCLIC AMP DEPENDENT PROTEIN KINASE; INTEGRIN; SERINE; THROMBIN RECEPTOR; THROMBOCYTE RECEPTOR; THROMBOCYTE RECEPTOR GPIB IX V COMPLEX; UNCLASSIFIED DRUG; VON WILLEBRAND FACTOR;

BERNARD SOULIER DISEASE; BLEEDING DISORDER; BLOOD VESSEL WALL; CYTOPLASM; ENZYME PHOSPHORYLATION; HEART INFARCTION; HEMOSTASIS; NONHUMAN; NOTE; PRIORITY JOURNAL; THROMBOCYTE ACTIVATION; THROMBOCYTE RICH PLASMA; THROMBOGENESIS; VASCULAR BIOLOGY; VASCULAR ENDOTHELIUM; VASCULAR PATENCY; VON WILLEBRAND DISEASE; ANIMAL; CHO CELL LINE; CRICETULUS; HAMSTER; METABOLISM; SIGNAL TRANSDUCTION;

ANIMALS; CHO CELLS; CRICETINAE; CRICETULUS; PLATELET GLYCOPROTEIN GPIB-IX COMPLEX; SIGNAL TRANSDUCTION;

EID: 77953752226     PISSN: 15387933     EISSN: 15387836     Source Type: Journal    
DOI: 10.1111/j.1538-7836.2009.03534.x     Document Type: Note

References (14)

1. David T, Strassel C, Eckly A, Cazenave JP, Gachet C, Lanza F. The platelet glycoprotein GPIbβ intracellular domain participates in von Willebrand factor-induced filopodia formation independently of the Ser166 phosphorylation site. J Thromb Haemost 2010, 8:1077-87.
2. Nieswandt B, Watson SP. Platelet-collagen interaction: is GPVI the central receptor? Blood 2003, 102:449-61.
3. Du X. Signaling and regulation of the platelet glycoprotein Ib-IX-V complex. Curr Opin Hematol 2007, 14:262-9.
4. Jackson SP, Nesbitt WS, Kulkarni S. Signaling events underlying thrombus formation. J Thromb Haemost 2003, 1:1602-12.
5. Andrews RK, Gardiner EE, Shen Y, Whisstock JC, Berndt MC. Glycoprotein Ib-IX-V. Int J Biochem Cell Biol 2003, 35:1170-4.
6. Jackson SP, Cranmer S, Mangin P, Yuan Y. Are Erk, Btk, and PECAM-1 major players in GPIb signaling? The challenge of unraveling signaling events downstream of platelet GPIb. Blood 2007, 109:846-7.
7. Liu J, Fitzgerald MEC, Berndt MC, Jackson CW, Gartner TK. Response: establishing the physiological significance in vivo answers the challenge of unraveling the details of GPIb-initiated signal transduction. Blood 2007, 109:847-8.
8. Kunapuli SP. Response: is there a physiologically relevant experimental model system to study GPIb-mediated signaling in platelets? Blood 2007, 109:848.
9. López JA, Leung B, Reynolds CC, Li CQ, Fox JE. Efficient plasma membrane expression of a functional platelet glycoprotein Ib-IX complex requires the presence of its three subunits. J Biol Chem 1992, 267:12851-9.
10. Gu M, Xi X, Englund GD, Berndt MC, Du X. Analysis of the roles of 14-3-3 in the platelet glycoprotein Ib-IX- mediated activation of integrin αIIbβ3 using a reconstituted mammalian cell expression model. J Cell Biol 1999, 147:1085-96.
11. Zaffran Y, Meyer SC, Negrescu E, Reddy KB, Fox JEB. Signaling across the platelet adhesion receptor glycoprotein Ib-IX induces αIIbβ3 activation both in platelets and a transfected chinese hamster ovary cell system. J Biol Chem 2000, 275:16779-87.
12. Yuan Y, Kulkarni S, Ulsemer P, Cranmer SL, Yap CL, Nesbitt WS, Harper I, Mistry N, Dopheide SM, Hughan SC, Williamson D, de la Salle C, Salem HH, Lanza F, Jackson SP. The von Willebrand factor-glycoprotein Ib/V/IX interaction induces actin polymerization and cytoskeletal reorganization in rolling platelets and glycoprotein Ib/V/IX-transfected cells. J Biol Chem 1999, 274:36241-51.
13. Mangin P, David T, Lavaud V, Cranmer SL, Pikovski I, Jackson SP, Berndt MC, Cazenave JP, Gachet C, Lanza F. Identification of a novel 14-3-3ζ binding site within the cytoplasmic tail of platelet glycoprotein Ibα. Blood 2004, 104:420-7.
14. Dai K, Bodnar R, Berndt MC, Du X. A critical role for 14-3-3ζ protein in regulating the VWF binding function of platelet glycoprotein Ib-IX and its therapeutic implications. Blood 2005, 106:1975-81.