Establishing the physiological significance in vivo answers the challenge of unraveling the details of GPIb-initiated signal transduction [6]

Blood

Volumn 109, Issue 2, 2007, Pages 847-848

  Liu, Junling ^b   Fitzgerald, Malinda E C ^b   Berndt, Michael C ^b   Jackson, Carl W ^b   Gartner, T Kent ^a  

^a UNIVERSITY OF MEMPHIS   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

BOTROCETIN; BRUTON TYROSINE KINASE; GLUCOSE 1 PHOSPHATE; THROMBOXANE A2;

CALCIUM TRANSPORT; HUMAN; IN VIVO STUDY; LETTER; LIGAND BINDING; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; THROMBOCYTE AGGREGATION;

EID: 33846210353     PISSN: 00064971     EISSN: 00064971     Source Type: Journal    
DOI: 10.1182/blood-2006-09-048397     Document Type: Letter

References (7)

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2. Liu J, Pestina TI, Berndt MC, Jackson CW, Gartner TK. Botrocetin/VWF-induced signaling through GPIb-IX-V produces TxA2 in an alphaIIbbeta3- and aggregation-independent manner. Blood. 2005;106:2750-2756.
3. Takata M, Kurosaki T. A role for Bruton's tyrosine kinase in B cell antigen receptor-mediated activation of phospholipase C-gamma 2. J Exp Med. 1996;184:31-40.
4. Liu J, Fitzgerald ME, Berndt MC, Jackson CW, Gartner TK. Bruton tyrosine kinase is essential for botrocetin/VWf-induced signaling and GPIb-dependent thrombus formation in vivo. Blood. Prepublished on June 20, 2006, as DOI 10.1182/blood-2006-01-011817. (Now available as Blood. 2006;108:2596-2603.)
5. Liu J, Pestina TI, Berndt MC, Steward SA, Jackson CW, Gartner TK. The roles of ADP and TXA in botrocetin/VWF-induced aggregation of washed platelets. J Thromb Haemost. 2004;2:2213-2222.
6. Kurz KD, Main BW, Sandusky GE. Rat model of arterial thrombosis induced by ferric chloride. Thromb Res. 1990;60:269-280.
7. Farrehi PM, Ozaki CK, Carmeliet P, Fay WP. Regulation of arterial thrombolysis by plasminogen activator inhibitor-1 in mice. Circulation. 1998;97:1002-1008.