Microtubule amplification in the assembly of mitotic spindle and the maturation of kinetochore fibers

Communicative and Integrative Biology

Volumn 2, Issue 3, 2009, Pages 208-210

  Zhu, Hui ^a   Fang, Kayleen ^a   Fang, Guowei ^a,b  

^a STANFORD UNIVERSITY   (United States)

^b GENENTECH INC   (United States)

Author keywords

FAM29A; k Fiber maturation; Microtubule amplification; Microtubule nucleation; Mitotic spindle assembly; NEDD1; Plk1

Indexed keywords

EID: 77953727793     PISSN: None     EISSN: 19420889     Source Type: Journal    
DOI: 10.4161/cib.2.3.7875     Document Type: Article

References (19)

1. Wiese C, Zheng Y. Microtubule nucleation: gamma-tubulin and beyond. J Cell Sci 2006; 119:4143-53.
2. Yuba-Kubo A, Kubo A, Hata M, Tsukita S. Gene knockout analysis of two gamma-tubulin isoforms in mice. Dev Biol 2005; 282:361-73.
3. Haren L, Remy MH, Bazin I, Callebaut I, Wright M, Merdes A. NEDD1-dependent recruitment of the gamma-tubulin ring complex to the centrosome is necessary for centriole duplication and spindle assembly. J Cell Biol 2006; 172:505-15.
4. Luders J, Patel UK, Stearns T. GCP-WD is a gamma-tubulin targeting factor required for centrosomal and chromatin-mediated microtubule nucleation. Nat Cell Biol 2006; 8:137-47.
5. Luders J, Stearns T. Microtubule-organizing centres: a re-evaluation. Nat Rev Mol Cell Biol 2007; 8:161-7.
6. Mahoney NM, Goshima G, Douglass AD, Vale RD. Making microtubules and mitotic spindles in cells without functional centrosomes. Curr Biol 2006; 16:564-9.
7. Bastiaens P, Caudron M, Niethammer P, Karsenti E. Gradients in the self-organization of the mitotic spindle. Trends Cell Biol 2006; 16:125-34.
8. Gruss OJ, Vernos I. The mechanism of spindle assembly: functions of Ran and its target TPX2. J Cell Biol 2004; 166:949-55.
9. Nachury MV, Maresca TJ, Salmon WC, Waterman-Storer CM, Heald R, Weis K. Importin beta is a mitotic target of the small GTPase Ran in spindle assembly. Cell 2001; 104:95-106.
10. Karsenti E, Vernos I. The mitotic spindle: a self-made machine. Science 2001; 294:543-7.
11. Zhu H, Coppinger JA, Jang CY, Yates JR, 3rd, Fang G. FAM29A promotes microtubule amplification via recruitment of the NEDD1-gamma-tubulin complex to the mitotic spindle. J Cell Biol 2008; 183:835-48.
12. van Vugt MA, van de Weerdt BC, Vader G, Janssen H, Calafat J, Klompmaker R, Wolthuis RM, Medema RH. Polo-like kinase-1 is required for bipolar spindle formation but is dispensable for anaphase promoting complex/Cdc20 activation and initiation of cytokinesis. J Biol Chem 2004; 279:36841-54.
13. Barr FA, Sillje HH, Nigg EA. Polo-like kinases and the orchestration of cell division. Nat Rev Mol Cell Biol 2004; 5:429-40.
14. Goshima G, Mayer M, Zhang N, Stuurman N, Vale RD. Augmin: a protein complex required for centrosome-independent microtubule generation within the spindle. J Cell Biol 2008; 181:421-9.
15. Maiato H, DeLuca J, Salmon ED, Earnshaw WC. The dynamic kinetochore-microtubule interface. J Cell Sci 2004; 117:5461-77.
16. Kirschner M, Mitchison T. Beyond self-assembly: from microtubules to morphogenesis. Cell 1986; 45:329-42.
17. McIntosh JR, Grishchuk EL, West RR. Chromosome-microtubule interactions during mitosis. Annu Rev Cell Dev Biol 2002; 18:193-219.
18. Murata T, Sonobe S, Baskin TI, Hyodo S, Hasezawa S, Nagata T, Horio T, Hasebe M. Microtubule-dependent microtubule nucleation based on recruitment of gamma-tubulin in higher plants. Nat Cell Biol 2005; 7:961-8.
19. Janson ME, Setty TG, Paoletti A, Tran PT. Efficient formation of bipolar microtubule bundles requires microtubule-bound gamma-tubulin complexes. J Cell Biol 2005; 169:297 308.