-
1
-
-
0034614637
-
The hallmarks of cancer
-
Hanahan D, Weinberg RA. The hallmarks of cancer. Cell 2000; 100:57-70.
-
(2000)
Cell
, vol.100
, pp. 57-70
-
-
Hanahan, D.1
Weinberg, R.A.2
-
2
-
-
36148978132
-
Role of mitogen-activated protein kinase phosphatases (MKPs) in cancer
-
Wu GS. Role of mitogen-activated protein kinase phosphatases (MKPs) in cancer. Cancer Metastasis Rev 2007; 26:579-85.
-
(2007)
Cancer Metastasis Rev
, vol.26
, pp. 579-585
-
-
Wu, G.S.1
-
3
-
-
54049141728
-
Mitogen-activated protein (MAP) kinase/MAP kinase phosphatase regulation: Roles in cell growth, death and cancer
-
Boutros T, Chevet E, Metrakos P. Mitogen-activated protein (MAP) kinase/MAP kinase phosphatase regulation: roles in cell growth, death and cancer. Pharmacol Rev 2008; 60:261-310.
-
(2008)
Pharmacol Rev
, vol.60
, pp. 261-310
-
-
Boutros, T.1
Chevet, E.2
Metrakos, P.3
-
4
-
-
37549025064
-
ERK-dependent MKP-1-mediated cisplatin resistance in human ovarian cancer cells
-
Wang J, Zhou JY, Wu GS. ERK-dependent MKP-1-mediated cisplatin resistance in human ovarian cancer cells. Cancer Res 2007; 67:11933-41.
-
(2007)
Cancer Res
, vol.67
, pp. 11933-11941
-
-
Wang, J.1
Zhou, J.Y.2
Wu, G.S.3
-
5
-
-
33646416743
-
The role of mitogen-activated protein kinase phosphatase-1 in oxidative damage-induced cell death
-
Zhou JY, Liu Y, Wu GS. The role of mitogen-activated protein kinase phosphatase-1 in oxidative damage-induced cell death. Cancer Res 2006; 66:4888-94.
-
(2006)
Cancer Res
, vol.66
, pp. 4888-4894
-
-
Zhou, J.Y.1
Liu, Y.2
Wu, G.S.3
-
6
-
-
33845693412
-
Diverse physiological functions for dual-specificity MAP kinase phosphatases
-
Dickinson RJ, Keyse SM. Diverse physiological functions for dual-specificity MAP kinase phosphatases. J Cell Sci 2006; 119:4607-15.
-
(2006)
J Cell Sci
, vol.119
, pp. 4607-4615
-
-
Dickinson, R.J.1
Keyse, S.M.2
-
7
-
-
0027423987
-
Amino acid sequence similarity between CL100, a dual-specificity MAP kinase phosphatase and cdc25
-
Keyse SM, Ginsburg M. Amino acid sequence similarity between CL100, a dual-specificity MAP kinase phosphatase and cdc25. Trends Biochem Sci 1993; 18:377-8.
-
(1993)
Trends Biochem Sci
, vol.18
, pp. 377-378
-
-
Keyse, S.M.1
Ginsburg, M.2
-
8
-
-
33847176551
-
MAPK phosphatases - Regulating the immune response
-
Liu Y, Shepherd EG, Nelin LD. MAPK phosphatases - regulating the immune response. Nat Rev Immunol 2007; 7:202-12.
-
(2007)
Nat Rev Immunol
, vol.7
, pp. 202-212
-
-
Liu, Y.1
Shepherd, E.G.2
Nelin, L.D.3
-
9
-
-
43049101029
-
Dual-specificity MAP kinase phosphatases (MKPs) and cancer
-
Keyse SM. Dual-specificity MAP kinase phosphatases (MKPs) and cancer. Cancer Metastasis Rev 2008; 27:253-61.
-
(2008)
Cancer Metastasis Rev
, vol.27
, pp. 253-261
-
-
Keyse, S.M.1
-
10
-
-
72549116624
-
Phase I/II trial of bevacizumab and radiotherapy for locally advanced inoperable colorectal cancer: Vasculature-independent radiosensitizing effect of bevacizumab
-
Koukourakis MI, Giatromanolaki A, Sheldon H, Buffa FM, Kouklakis G, Ragoussis I, et al. Phase I/II trial of bevacizumab and radiotherapy for locally advanced inoperable colorectal cancer: vasculature-independent radiosensitizing effect of bevacizumab. Clin Cancer Res 2009; 15:7069-76.
-
(2009)
Clin Cancer Res
, vol.15
, pp. 7069-7076
-
-
Koukourakis, M.I.1
Giatromanolaki, A.2
Sheldon, H.3
Buffa, F.M.4
Kouklakis, G.5
Ragoussis, I.6
-
11
-
-
0037058703
-
Expression of mitogen-activated protein kinase phosphatase-1 (MKP-1) in primary human ovarian carcinoma
-
Denkert C, Schmitt WD, Berger S, Reles A, Pest S, Siegert A, et al. Expression of mitogen-activated protein kinase phosphatase-1 (MKP-1) in primary human ovarian carcinoma. Int J Cancer 2002; 102:507-13.
-
(2002)
Int J Cancer
, vol.102
, pp. 507-513
-
-
Denkert, C.1
Schmitt, W.D.2
Berger, S.3
Reles, A.4
Pest, S.5
Siegert, A.6
-
12
-
-
33748995966
-
Mitogen-activated protein kinase phosphatase-1 is required for cisplatin resistance
-
Wang Z, Xu J, Zhou JY, Liu Y, Wu GS. Mitogen-activated protein kinase phosphatase-1 is required for cisplatin resistance. Cancer Res 2006; 66:8870-7.
-
(2006)
Cancer Res
, vol.66
, pp. 8870-8877
-
-
Wang, Z.1
Xu, J.2
Zhou, J.Y.3
Liu, Y.4
Wu, G.S.5
-
13
-
-
34249320861
-
Mitogen-activated protein kinase phosphatase-1 is a mediator of breast cancer chemoresistance
-
Small GW, Shi YY, Higgins LS, Orlowski RZ. Mitogen-activated protein kinase phosphatase-1 is a mediator of breast cancer chemoresistance. Cancer Res 2007; 67:4459-66.
-
(2007)
Cancer Res
, vol.67
, pp. 4459-4466
-
-
Small, G.W.1
Shi, Y.Y.2
Higgins, L.S.3
Orlowski, R.Z.4
-
14
-
-
0033970533
-
Dual specificity phosphatases: A gene family for control of MAP kinase function
-
Camps M, Nichols A, Arkinstall S. Dual specificity phosphatases: a gene family for control of MAP kinase function. FASEB J 2000; 14:6-16. (Pubitemid 30051518)
-
(2000)
FASEB Journal
, vol.14
, Issue.1
, pp. 6-16
-
-
Camps, M.1
Nichols, A.2
Arkinstall, S.3
-
15
-
-
0037430452
-
Overexpression of mitogen-activated protein kinase phosphatases MKP1, MKP2 in human breast cancer
-
Wang HY, Cheng Z, Malbon CC. Overexpression of mitogen-activated protein kinase phosphatases MKP1, MKP2 in human breast cancer. Cancer Lett 2003; 191:229-37.
-
(2003)
Cancer Lett
, vol.191
, pp. 229-237
-
-
Wang, H.Y.1
Cheng, Z.2
Malbon, C.C.3
-
16
-
-
0031590439
-
The characteristic gene expressions of MAPK phosphatases 1 and 2 in hepatocarcinogenesis, rat ascites hepatoma cells, and regenerating rat liver
-
Yokoyama A, Karasaki H, Urushibara N, Nomoto K, Imai Y, Nakamura K, et al. The characteristic gene expressions of MAPK phosphatases 1 and 2 in hepatocarcinogenesis, rat ascites hepatoma cells, and regenerating rat liver. Biochem Biophys Res Commun 1997; 239:746-51.
-
(1997)
Biochem Biophys Res Commun
, vol.239
, pp. 746-751
-
-
Yokoyama, A.1
Karasaki, H.2
Urushibara, N.3
Nomoto, K.4
Imai, Y.5
Nakamura, K.6
-
17
-
-
0034813635
-
Pancreatic tumor cells with mutant K-ras suppress ERK activity by MEK-dependent induction of MAP kinase phosphatase-2
-
Yip-Schneider MT, Lin A, Marshall MS. Pancreatic tumor cells with mutant K-ras suppress ERK activity by MEK-dependent induction of MAP kinase phosphatase-2. Biochem Biophys Res Commun 2001; 280:992-7.
-
(2001)
Biochem Biophys Res Commun
, vol.280
, pp. 992-997
-
-
Yip-Schneider, M.T.1
Lin, A.2
Marshall, M.S.3
-
18
-
-
0038243934
-
Potential tumor suppressive pathway involving DUSP6/MKP-3 in pancreatic cancer
-
Furukawa T, Sunamura M, Motoi F, Matsuno S, Horii A. Potential tumor suppressive pathway involving DUSP6/MKP-3 in pancreatic cancer. Am J Pathol 2003; 162:1807-15. (Pubitemid 36613039)
-
(2003)
American Journal of Pathology
, vol.162
, Issue.6
, pp. 1807-1815
-
-
Furukawa, T.1
Sunamura, M.2
Motoi, F.3
Matsuno, S.4
Horii, A.5
-
19
-
-
24044529771
-
Distinct progression pathways involving the dysfunction of DUSP6/MKP-3 in pancreatic intraepithelial neoplasia and intraductal papillary-mucinous neoplasms of the pancreas
-
Furukawa T, Fujisaki R, Yoshida Y, Kanai N, Sunamura M, Abe T, et al. Distinct progression pathways involving the dysfunction of DUSP6/MKP-3 in pancreatic intraepithelial neoplasia and intraductal papillary-mucinous neoplasms of the pancreas. Mod Pathol 2005; 18:1034-42.
-
(2005)
Mod Pathol
, vol.18
, pp. 1034-1042
-
-
Furukawa, T.1
Fujisaki, R.2
Yoshida, Y.3
Kanai, N.4
Sunamura, M.5
Abe, T.6
-
20
-
-
4043182010
-
Mitogen-activated protein kinase phosphatase-3 is a tumor promoter target in initiated cells that express oncogenic Ras
-
Warmka JK, Mauro LJ, Wattenberg EV. Mitogen-activated protein kinase phosphatase-3 is a tumor promoter target in initiated cells that express oncogenic Ras. J Biol Chem 2004; 279:33085-92.
-
(2004)
J Biol Chem
, vol.279
, pp. 33085-33092
-
-
Warmka, J.K.1
Mauro, L.J.2
Wattenberg, E.V.3
-
21
-
-
33745241078
-
Elevated expression of mitogen-activated protein kinase phosphatase 3 in breast tumors: A mechanism of tamoxifen resistance
-
Cui Y, Parra I, Zhang M, Hilsenbeck SG, Tsimelzon A, Furukawa T, et al. Elevated expression of mitogen-activated protein kinase phosphatase 3 in breast tumors: a mechanism of tamoxifen resistance. Cancer Res 2006; 66:5950-9.
-
(2006)
Cancer Res
, vol.66
, pp. 5950-5959
-
-
Cui, Y.1
Parra, I.2
Zhang, M.3
Hilsenbeck, S.G.4
Tsimelzon, A.5
Furukawa, T.6
-
22
-
-
51849123638
-
Loss of MKP3 mediated by oxidative stress enhances tumorigenicity and chemoresistance of ovarian cancer cells
-
Chan DW, Liu VW, Tsao GS, Yao KM, Furukawa T, Chan KK, et al. Loss of MKP3 mediated by oxidative stress enhances tumorigenicity and chemoresistance of ovarian cancer cells. Carcinogenesis 2008; 29:1742-50.
-
(2008)
Carcinogenesis
, vol.29
, pp. 1742-1750
-
-
Chan, D.W.1
Liu, V.W.2
Tsao, G.S.3
Yao, K.M.4
Furukawa, T.5
Chan, K.K.6
-
23
-
-
1942444497
-
The PAC-1 dual specificity phosphatase predicts poor outcome in serous ovarian carcinoma
-
Givant-Horwitz V, Davidson B, Goderstad JM, Nesland JM, Trope CG, Reich R. The PAC-1 dual specificity phosphatase predicts poor outcome in serous ovarian carcinoma. Gynecol Oncol 2004; 93:517-23.
-
(2004)
Gynecol Oncol
, vol.93
, pp. 517-523
-
-
Givant-Horwitz, V.1
Davidson, B.2
Goderstad, J.M.3
Nesland, J.M.4
Trope, C.G.5
Reich, R.6
-
24
-
-
24344455502
-
The dual-specificity protein phosphatase DUSP9/MKP-4 is essential for placental function but is not required for normal embryonic development
-
Christie GR, Williams DJ, Macisaac F, Dickinson RJ, Rosewell I, Keyse SM. The dual-specificity protein phosphatase DUSP9/MKP-4 is essential for placental function but is not required for normal embryonic development. Mol Cell Biol 2005; 25:8323-33.
-
(2005)
Mol Cell Biol
, vol.25
, pp. 8323-8333
-
-
Christie, G.R.1
Williams, D.J.2
Macisaac, F.3
Dickinson, R.J.4
Rosewell, I.5
Keyse, S.M.6
-
25
-
-
36349030782
-
Microtubule disruption and tumor suppression by mitogen-activated protein kinase phosphatase 4
-
Liu Y, Lagowski J, Sundholm A, Sundberg A, Kulesz-Martin M. Microtubule disruption and tumor suppression by mitogen-activated protein kinase phosphatase 4. Cancer Res 2007; 67:10711-9.
-
(2007)
Cancer Res
, vol.67
, pp. 10711-10719
-
-
Liu, Y.1
Lagowski, J.2
Sundholm, A.3
Sundberg, A.4
Kulesz-Martin, M.5
-
26
-
-
0344873757
-
MAPK phosphatase DUSP16/MKP-7, a candidate tumor suppressor for chromosome region 12p12-13, reduces BCR-ABL- Induced transformation
-
Hoornaert I, Marynen P, Goris J, Sciot R, Baens M. MAPK phosphatase DUSP16/MKP-7, a candidate tumor suppressor for chromosome region 12p12-13, reduces BCR-ABL- induced transformation. Oncogene 2003; 22:7728-36.
-
(2003)
Oncogene
, vol.22
, pp. 7728-7736
-
-
Hoornaert, I.1
Marynen, P.2
Goris, J.3
Sciot, R.4
Baens, M.5
-
27
-
-
70350521699
-
Altered Runx1 subnuclear targeting enhances myeloid cell proliferation and blocks differentiation by activating a miR-24/MKP-7/MAPK network
-
Zaidi SK, Dowdy CR, van Wijnen AJ, Lian JB, Raza A, Stein JL, et al. Altered Runx1 subnuclear targeting enhances myeloid cell proliferation and blocks differentiation by activating a miR-24/MKP-7/MAPK network. Cancer Res 2009; 69:8249-55.
-
(2009)
Cancer Res
, vol.69
, pp. 8249-8255
-
-
Zaidi, S.K.1
Dowdy, C.R.2
Van Wijnen, A.J.3
Lian, J.B.4
Raza, A.5
Stein, J.L.6
-
28
-
-
56749173830
-
High level of mitogen-activated protein kinase phosphatase-1 expression is associated with cisplatin resistance in osteosarcoma
-
Wang Z, Zhou JY, Kanakapalli D, Buck S, Wu GS, Ravindranath Y. High level of mitogen-activated protein kinase phosphatase-1 expression is associated with cisplatin resistance in osteosarcoma. Pediatr Blood Cancer 2008; 51:754-9.
-
(2008)
Pediatr Blood Cancer
, vol.51
, pp. 754-759
-
-
Wang, Z.1
Zhou, J.Y.2
Kanakapalli, D.3
Buck, S.4
Wu, G.S.5
Ravindranath, Y.6
-
29
-
-
70349916269
-
Involvement of MKP-1 and Bcl-2 in acquired cisplatin resistance in ovarian cancer cells
-
Wang J, Zhou JY, Zhang L, Wu GS. Involvement of MKP-1 and Bcl-2 in acquired cisplatin resistance in ovarian cancer cells. Cell Cycle 2009; 8:3191-8.
-
(2009)
Cell Cycle
, vol.8
, pp. 3191-3198
-
-
Wang, J.1
Zhou, J.Y.2
Zhang, L.3
Wu, G.S.4
-
30
-
-
34249288309
-
Implementation of high-content assay for inhibitors of mitogen-activated protein kinase phosphatases
-
Vogt A, Lazo JS. Implementation of high-content assay for inhibitors of mitogen-activated protein kinase phosphatases. Methods 2007; 42:268-77.
-
(2007)
Methods
, vol.42
, pp. 268-277
-
-
Vogt, A.1
Lazo, J.S.2
-
31
-
-
39749109385
-
A cell-active inhibitor of mitogen-activated protein kinase phosphatases restores paclitaxel-induced apoptosis in dexamethasone-protected cancer cells
-
Vogt A, McDonald PR, Tamewitz A, Sikorski RP, Wipf P, Skoko JJ, et al. A cell-active inhibitor of mitogen-activated protein kinase phosphatases restores paclitaxel-induced apoptosis in dexamethasone-protected cancer cells. Mol Cancer Ther 2008; 7:330-40.
-
(2008)
Mol Cancer Ther
, vol.7
, pp. 330-340
-
-
Vogt, A.1
McDonald, P.R.2
Tamewitz, A.3
Sikorski, R.P.4
Wipf, P.5
Skoko, J.J.6
-
32
-
-
33847138939
-
Synthesis and biological activity of a focused library of mitogen-activated protein kinase phosphatase inhibitors
-
Arnold DM, Foster C, Huryn DM, Lazo JS, Johnston PA, Wipf P. Synthesis and biological activity of a focused library of mitogen-activated protein kinase phosphatase inhibitors. Chem Biol Drug Des 2007; 69:23-30.
-
(2007)
Chem Biol Drug des
, vol.69
, pp. 23-30
-
-
Arnold, D.M.1
Foster, C.2
Huryn, D.M.3
Lazo, J.S.4
Johnston, P.A.5
Wipf, P.6
-
33
-
-
34548081190
-
Structurally unique inhibitors of human mitogen-activated protein kinase phosphatase-1 identified in a pyrrole carboxamide library
-
Lazo JS, Skoko JJ, Werner S, Mitasev B, Bakan A, Koizumi F, et al. Structurally unique inhibitors of human mitogen-activated protein kinase phosphatase-1 identified in a pyrrole carboxamide library. J Pharmacol Exp Ther 2007; 322:940-7.
-
(2007)
J Pharmacol Exp Ther
, vol.322
, pp. 940-947
-
-
Lazo, J.S.1
Skoko, J.J.2
Werner, S.3
Mitasev, B.4
Bakan, A.5
Koizumi, F.6
|