Intrathecal injection of carbenoxolone, a gap junction decoupler, attenuates the induction of below-level neuropathic pain after spinal cord injury in rats

Experimental Neurology

Volumn 224, Issue 1, 2010, Pages 123-132

  Roh, Dae Hyun ^a   Yoon, Seo Yeon ^b   Seo, Hyoung Sig ^c   Kang, Suk Yun ^c   Han, Ho Jae ^a   Beitz, Alvin J ^d   Lee, Jang Hern ^c  

^a Chonnam National University   (South Korea)

^b UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^c Seoul National University   (South Korea)

^d UNIVERSITY OF MINNESOTA   (United States)

Author keywords

Astrocyte; Carbenoxolone; Gap junction; Neuropathic pain; NMDA receptor; Spinal cord injury

Indexed keywords

CARBENOXOLONE; GLIAL FIBRILLARY ACIDIC PROTEIN; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 1;

ALLODYNIA; ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; CELL ACTIVATION; CELL COUNT; CONTROLLED STUDY; CONVALESCENCE; DRUG DOSE COMPARISON; GAP JUNCTION; HYPERALGESIA; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; LUMBAR SPINAL CORD; MALE; MOTOR PERFORMANCE; NEUROPATHIC PAIN; NOCICEPTION; NONHUMAN; POSTOPERATIVE PERIOD; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; SPINAL CORD DORSAL HORN; SPINAL CORD HEMISECTION; SPINAL CORD INJURY;

ANALYSIS OF VARIANCE; ANIMALS; ASTROCYTES; CARBENOXOLONE; DOSE-RESPONSE RELATIONSHIP, DRUG; GAP JUNCTIONS; GLIAL FIBRILLARY ACIDIC PROTEIN; IMAGE PROCESSING, COMPUTER-ASSISTED; IMMUNOHISTOCHEMISTRY; INJECTIONS, SPINAL; MALE; MOTOR ACTIVITY; NEURALGIA; PAIN MEASUREMENT; PHOSPHORYLATION; POSTERIOR HORN CELLS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, N-METHYL-D-ASPARTATE; RECOVERY OF FUNCTION; SPINAL CORD; SPINAL CORD INJURIES; THORACIC VERTEBRAE;

EID: 77953718410     PISSN: 00144886     EISSN: 10902430     Source Type: Journal    
DOI: 10.1016/j.expneurol.2010.03.002     Document Type: Article

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