Budesonide treatment of patients with collagenous colitis restores normal eosinophil and T-cell activity in the colon

Inflammatory Bowel Diseases

Volumn 16, Issue 7, 2010, Pages 1118-1126

  Wagner, Michael ^a   Lampinen, Maria ^a   Sangfelt, Per ^a   Agnarsdottir, Margret ^a   Carlson, Marie ^a  

^a UPPSALA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Budesonide; Collagenous colitis; Eosinophil; Flow cytometry; T lymphocyte

Indexed keywords

ANTIGEN; BUDESONIDE; CD66B ANTIGEN; CD69 ANTIGEN; CD9 ANTIGEN; HERMES ANTIGEN; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; CELL ACTIVATION; CLINICAL ARTICLE; COLLAGENOUS COLITIS; COLON; CONTROLLED STUDY; EOSINOPHIL; FEMALE; FLOW CYTOMETRY; HUMAN; HUMAN TISSUE; INTESTINE BIOPSY; MALE; NEUTROPHIL; PRIORITY JOURNAL; T LYMPHOCYTE; T LYMPHOCYTE ACTIVATION;

ADULT; AGED; ANTI-INFLAMMATORY AGENTS; ANTIGENS, CD; ANTIGENS, DIFFERENTIATION, T-LYMPHOCYTE; BUDESONIDE; COLITIS, COLLAGENOUS; EOSINOPHILS; FEMALE; FLOW CYTOMETRY; HUMANS; IMMUNOENZYME TECHNIQUES; LECTINS, C-TYPE; LYMPHOCYTE ACTIVATION; MALE; MIDDLE AGED; NEUTROPHIL ACTIVATION; NEUTROPHILS; T-LYMPHOCYTES; YOUNG ADULT;

EID: 77953715354     PISSN: 10780998     EISSN: 15364844     Source Type: Journal    
DOI: 10.1002/ibd.21188     Document Type: Article

References (57)

1. Lindstrom CG. 'Collagenous colitis' with watery diarrhoea - a new entity? Pathol Eur. 1976;11:87-89.
2. Bohr J, Tysk C, Eriksson S, et al. Collagenous colitis: a retrospective study of clinical presentation and treatment in 163 patients. Gut. 1996;39:846-851. (Pubitemid 27049088)
3. Olesen M, Eriksson S, Bohr J, et al. Microscopic colitis: a common diarrhoeal disease. An epidemiological study in Orebro, Sweden, 1993-1998. Gut. 2004;53:346-350.
4. Pardi DS, Loftus EV Jr, Smyrk TC, et al. The epidemiology of microscopic colitis: a population based study in Olmsted County, Minnesota. Gut. 2007;56:504-508.
5. Warren BF, Edwards CM, Travis SP. 'Microscopic colitis': classification and terminology. Histopathology. 2002;40:374-376.
6. Tysk C, Bohr J, Nyhlin N, et al. Diagnosis and management of microscopic colitis. World J Gastroenterol. 2008;14:7280-7288.
7. Freeman HJ. Perinuclear antineutrophil cytoplasmic antibodies in collagenous or lymphocytic colitis with or without celiac disease. Can J Gastroenterol. 1997;11:417-420.
8. Bohr J, Tysk C, Yang P, et al. Autoantibodies and immunoglobulins in collagenous colitis. Gut. 1996;39:73-76.
9. Ung KA, Gillberg R, Kilander A, et al. Role of bile acids and bile acid binding agents in patients with collagenous colitis. Gut. 2000;46:170-175.
10. Beaugerie L, Pardi DS. Review article: drug-induced microscopic colitis - proposal for a scoring system and review of the literature. Aliment Pharmacol Ther. 2005;22:277-284.
11. Bohr J, Nordfelth R, Jarnerot G, et al. Yersinia species in collagenous colitis: a serologic study. Scand J Gastroenterol. 2002;37:711-714.
12. Jarnerot G, Tysk C, Bohr J, et al. Collagenous colitis and fecal stream diversion. Gastroenterology. 1995;109:449-455.
13. Munch A, Soderholm JD, Ost A, et al. Increased transmucosal uptake of E. coli K12 in collagenous colitis persists after budesonide treatment. Am J Gastroenterol. 2009;104:679-685.
14. Chande N, MacDonald JK, McDonald JW. Interventions for treating microscopic colitis: a Cochrane Inflammatory Bowel Disease and Functional Bowel Disorders Review Group systematic review of randomized trials. Am J Gastroenterol. 2009;104:235-241; quiz 4, 42.
15. Miehlke S, Madisch A, Voss C, et al. Long-term follow-up of collagenous colitis after induction of clinical remission with budesonide. Aliment Pharmacol Ther. 2005;22:1115-1119. (Pubitemid 41779519)
16. Lazenby AJ, Yardley JH, Giardiello FM, et al. Pitfalls in the diagnosis of collagenous colitis: experience with 75 cases from a registry of collagenous colitis at the Johns Hopkins Hospital. Hum Pathol. 1990;21:905-910.
17. Offner FA, Jao RV, Lewin KJ, et al. Collagenous colitis: a study of the distribution of morphological abnormalities and their histological detection. Hum Pathol. 1999;30:451-457.
18. Jessurun J, Yardley JH, Giardiello FM, et al. Chronic colitis with thickening of the subepithelial collagen layer (collagenous colitis): histopathologic findings in 15 patients. Hum Pathol. 1987;18:839-848. (Pubitemid 18049857)
19. Venge P. The human eosinophil in inflammation. Agents Actions. 1990;29:122-126.
20. Venge P. The eosinophil granulocyte in allergic inflammation. Pediatr Allergy Immunol. 1993;4:19-24.
21. Woerly G, Roger N, Loiseau S, et al. Expression of CD28 and CD86 by human eosinophils and role in the secretion of type 1 cytokines (interleukin 2 and interferon gamma): inhibition by immunoglobulin a complexes. J Exp Med. 1999;190:487-495.
22. Taha Y, Carlson M, Thorn M, et al. Evidence of local eosinophil activation and altered mucosal permeability in collagenous colitis. Dig Dis Sci. 2001;46:888-897.
23. Levy AM, Yamazaki K, Van Keulen VP, et al. Increased eosinophil infiltration and degranulation in colonic tissue from patients with collagenous colitis. Am J Gastroenterol. 2001;96:1522-1528.
24. Taha Y, Raab Y, Carlson M, et al. Steroids reduce local inflammatory mediator secretion and mucosal permeability in collagenous colitis patients. World J Gastroenterol. 2006;12:7012-7018.
25. Panes J, Granger DN. Leukocyte-endothelial cell interactions: molecular mechanisms and implications in gastrointestinal disease. Gastroenterology. 1998;114:1066-1090.
26. Saverymuttu SH, Camilleri M, Rees H, et al. Indium 111-granulocyte scanning in the assessment of disease extent and disease activity in inflammatory bowel disease. A comparison with colonoscopy, histology, and fecal indium 111-granulocyte excretion. Gastroenterology. 1986;90:1121-1128.
27. Carlson M, Raab Y, Seveus L, et al. Human neutrophil lipocalin is a unique marker of neutrophil inflammation in ulcerative colitis and proctitis. Gut. 2002;50:501-506.
28. O'Morain C, Smethurst P, Levi AJ, et al. Biochemical analysis of enzymic markers of inflammation in rectal biopsies from patients with ulcerative colitis and Crohn's disease. J Clin Pathol. 1983;36:1312-1316. (Pubitemid 14205418)
29. Zins BJ, Tremaine WJ, Carpenter HA. Collagenous colitis: mucosal biopsies and association with fecal leukocytes. Mayo Clinic Proc. 1995;70:430-433.
30. Gubbins GP, Dekovich AA, Ma CK, et al. Collagenous colitis: report of nine cases and review of the literature. South Med J. 1991;84:33-37.
31. Mosnier JF, Larvol L, Barge J, et al. Lymphocytic and collagenous colitis: an immunohistochemical study. Am J Gastroenterol. 1996;91:709-713. (Pubitemid 126733806)
32. Tagkalidis PP, Gibson PR, Bhathal PS. Microscopic colitis demonstrates a T helper cell type 1 mucosal cytokine profile. J Clin Pathol. 2007;60:382-387.
33. Bonderup OK, Hansen JB, Birket-Smith L, et al. Budesonide treatment of collagenous colitis: a randomised, double blind, placebo controlled trial with morphometric analysis. Gut. 2003;52:248-251.
34. Bonderup OK, Hansen JB, Teglbjaerg PS, et al. Long-term budesonide treatment of collagenous colitis: a randomised, double-blind, placebocontrolled trial. Gut. 2009;58:68-72.
35. Carlson M, Raab Y, Peterson C, et al. Increased intraluminal release of eosinophil granule proteins EPO, ECP, EPX, and cytokines in ulcerative colitis and proctitis in segmental perfusion. Am J Gastroenterol. 1999;94:1876-1883.
36. Peterson CG, Eklund E, Taha Y, et al. A new method for the quantification of neutrophil and eosinophil cationic proteins in feces: establishment of normal levels and clinical application in patients with inflammatory bowel disease. Am J Gastroenterol. 2002;97:1755-1762.
37. Sangfelt P, Carlson M, Thorn M, et al. Neutrophil and eosinophil granule proteins as markers of response to local prednisolone treatment in distal ulcerative colitis and proctitis. Am J Gastroenterol. 2001;96:1085-1090.
38. Lampinen M, Ronnblom A, Amin K, et al. Eosinophil granulocytes are activated during the remission phase of ulcerative colitis. Gut. 2005;54:1714-1720.
39. Torsteinsdottir I, Arvidson NG, Hallgren R, et al. Enhanced expression of integrins and CD66b on peripheral blood neutrophils and eosinophils in patients with rheumatoid arthritis, and the effect of glucocorticoids. Scand J Immunol. 1999;50:433-439.
40. Stahle-Backdahl M, Maim J, Veress B, et al. Increased presence of eosinophilic granulocytes expressing transforming growth factor-beta1 in collagenous colitis. Scand J Gastroenterol. 2000;35:742-746.
41. Gleich GJ, Frigas E, Loegering DA, et al. Cytotoxic properties of the eosinophil major basic protein. J Immunol. 1979;123:2925-2927. (Pubitemid 10202545)
42. Metwali A, Blum AM, Ferraris L, et al. Eosinophils within the healthy or inflamed human intestine produce substance P and vasoactive intestinal peptide. J Neuroimmunol. 1994;52:69-78.
43. Birkland TP, Cheavens MD, Pincus SH. Human eosinophils stimulate DNA synthesis and matrix production in dermal fibroblasts. Arch Dermatol Res. 1994;286:312-318.
44. Pincus SH, Ramesh KS, Wyler DJ. Eosinophils stimulate fibroblast DNA synthesis. Blood. 1987;70:572-4.
45. Roberts AB, Sporn MB, Assoian RK, et al. Transforming growth factor type beta: rapid induction of fibrosis and angiogenesis in vivo and stimulation of collagen formation in vitro. Proc Natl Acad Sci USA. 1986;83:4167-4171.
46. Ignotz RA, Massague J. Transforming growth factor-beta stimulates the expression of fibronectin and collagen and their incorporation into the extracellular matrix. J Biol Chem. 1986;261:4337-4345. (Pubitemid 17198877)
47. Edwards DR, Murphy G, Reynolds JJ, et al. Transforming growth factor beta modulates the expression of collagenase and metalloproteinase inhibitor. EMBO J. 1987;6:1899-1904.
48. Jacoby DB, Ueki IF, Widdicombe JH, et al. Effect of human eosinophil major basic protein on ion transport in dog tracheal epithelium. Am Rev Resp Dis. 1988;137:13-16.
49. Minnicozzi M, Duran WN, Gleich GJ, et al. Eosinophil granule proteins increase microvascular macromolecular transport in the hamster cheek pouch. J Immunol. 1994;153:2664-2670. (Pubitemid 24278136)
50. Dajotoy T, Andersson P, Bjartell A, et al. Human eosinophils produce the T cell-attracting chemokines MIG and IP-10 upon stimulation with IFN-gamma. J Leuk Biol. 2004;76:685-691.
51. Chiappara G, Gagliardo R, Siena A, et al. Airway remodelling in the pathogenesis of asthma. Curr Opin Allergy Clin Immunol. 2001;1:85-93.
52. Walsh GM, Sexton DW, Blaylock MG. Corticosteroids, eosinophils and bronchial epithelial cells: new insights into the resolution of inflammation in asthma. J Endocrinol. 2003;178:37-43.
53. Beckett PA, Howarth PH. Pharmacotherapy and airway remodelling in asthma? Thorax. 2003;58:163-174.
54. Sloth H, Bisgaard C, Grove A. Collagenous colitis: a prospective trial of prednisolone in six patients. J Intern Med. 1991;229:443-436.
55. Nyhlin N, Bohr J, Eriksson S, et al. Microscopic colitis: a common and an easily overlooked cause of chronic diarrhoea. Eur J Intern Med. 2008;19:181-186.
56. Chande N, Driman DK, Reynolds RP. Collagenous colitis and lymphocytic colitis: patient characteristics and clinical presentation. Scand J Gastroenterol. 2005;40:343-347.
57. Elitsur Y, Lichtman SN, Neace C, et al. Immunosuppressive effect of budesonide on human lamina propria lymphocytes. Immunopharmacology. 1998;38:279-285.