Steroids reduce local inflammatory mediator secretion and mucosal permeability in collagenous colitis patients

World Journal of Gastroenterology

Volumn 12, Issue 43, 2006, Pages 7012-7018

  Taha, Yesuf ^a   Raab, Yngve ^a   Carlson, Marie ^a   Larsson, Anders ^a   Lördal, Mikael ^b   Lööf, Lars ^c   Thörn, Magnus ^d  

^a UPPSALA UNIVERSITY HOSPITAL   (Sweden)

^b KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^c CENTRAL HOSPITAL   (Sweden)

^d STOCKHOLM SÖDER HOSPITAL   (Sweden)

Author keywords

Basic fibroblast growth factor; Collagenous colitis; Eosinophil cationic protein; Inflammatory mediator; Steroid treatment; Vascular endothelial growth factor

Indexed keywords

ALBUMIN; BASIC FIBROBLAST GROWTH FACTOR; EOSINOPHIL CATIONIC PROTEIN; MYELOPEROXIDASE; PHOSPHORAL; PREDNISOLONE; SODIUM DIHYDROGEN PHOSPHATE; STEROID; VASCULOTROPIN;

ADULT; AGED; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CLINICAL ARTICLE; COLLAGENOUS COLITIS; COLON MUCOSA; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CORRELATION ANALYSIS; CYTOKINE RELEASE; DATA ANALYSIS; DEFECATION; DRUG DOSE REDUCTION; DRUG EFFECT; DRUG RESPONSE; FEMALE; HUMAN; IMMUNOCHEMISTRY; MALE; PATHOPHYSIOLOGY; PATIENT MONITORING; PERMEABILITY; PROTEIN FUNCTION; PROTEIN SECRETION; RECTUM MUCOSA; TISSUE PERFUSION; WELLBEING;

EID: 33751506066     PISSN: 10079327     EISSN: None     Source Type: Journal    
DOI: 10.3748/wjg.v12.i43.7012     Document Type: Article

References (42)

1. Jawhari A, Talbot IC. Microscopic, lymphocytic and collagenous colitis. Histopathology 1996; 29:101-110
2. Bogomoletz WV. Collagenous, microscopic and lymphocytic colitis. An evolving concept. Virchows Arch 1994; 424: 573-579
3. Jessurun J, Yardley JH, Giardiello FM, Hamilton SR, Bayless TM. Chronic colitis with thickening of the subepithelial collagen layer (collagenous colitis): histopathologic findings in 15 patients. Hum Pathol 1987; 18: 839-848
4. Aigner T, Neureiter D, Muller S, Kuspert G, Belke J, Kirchner T. Extracellular matrix composition and gene expression in collagenous colitis. Gastroenterology 1997; 113: 136-143
5. Tagkalidis P, Bhathal P, Gibson P. Microscopic colitis. J Gastroenterol Hepatol 2002; 17: 236-248
6. Moqbel R, Levi-Schaffer F, Kay AB. Cytokine generation by eosinophils. J Allergy Clin Immunol 1994; 94: 1183-1188
7. Horiuchi T, Weller PF. Expression of vascular endothelial growth factor by human eosinophils: upregulation by granulocyte macrophage colony-stimulating factor and interleukin-5. Am J Respir Cell Mol Biol 1997; 17: 70-77
8. Weller PF. The immunobiology of eosinophils. N Engl J Med 1991; 324: 1110-1118
9. Metwali A, Blum AM, Ferraris L, Klein JS, Fiocchi C, Weinstock JV. Eosinophils within the healthy or inflamed human intestine produce substance P and vasoactive intestinal peptide. J Neuroimmunol 1994; 52: 69-78
10. Williams TJ. The eosinophil enigma. J Clin Invest 2004; 113: 507-509
11. Powell DW, Mifflin RC, Valentich JD, Crowe SE, Saada JI, West AB. Myofibroblasts. II. Intestinal subepithelial myofibroblasts. Am J Physiol 1999; 277: C183-C201
12. Lawrance IC, Maxwell L, Doe W. Altered response of intestinal mucosal fibroblasts to profibrogenic cytokines in inflammatory bowel disease. Inflamm Bowel Dis 2001; 7: 226-236
13. Salas A, Fernandez-Banares F, Casalots J, Gonzalez C, Tarroch X, Forcada P, Gonzalez G. Subepithelial myofibroblasts and tenascin expression in microscopic colitis. Histopathology 2003; 43: 48-54
14. Redington AE, Roche WR, Madden J, Frew AJ, Djukanovic R, Holgate ST, Howarth PH. Basic fibroblast growth factor in asthma: measurement in bronchoalveolar lavage fluid basally and following allergen challenge. J Allergy Clin Immunol 2001; 107: 384-387
15. Thorn M, Raab Y, Larsson A, Gerdin B, Hallgren R. Intestinal mucosal secretion of basic fibroblast growth factor in patients with ulcerative colitis. Scand J Gastroenterol 2000; 35: 408-412
16. Taha Y, Raab Y, Larsson A, Carlson M, Loof L, Gerdin B, Thorn M. Mucosal secretion and expression of basic fibroblast growth factor in patients with collagenous colitis. Am J Gastroenterol 2003; 98: 2011-2017
17. Suzuma K, Naruse K, Suzuma I, Takahara N, Ueki K, Aiello LP, King GL. Vascular endothelial growth factor induces expression of connective tissue growth factor via KDR, Flt1, and phosphatidylinositol 3-kinase-akt-dependent pathways in retinal vascular cells. J Biol Chem 2000; 275: 40725-40731
18. Griga T, Tromm A, Schmiegel W, Pfisterer O, Muller KM, Brasch F. Collagenous colitis: implications for the role of vascular endothelial growth factor in repair mechanisms. Eur J Gastroenterol Hepatol 2004; 16: 397-402
19. Chiappara G, Gagliardo R, Siena A, Bonsignore MR, Bousquet J, Bonsignore G, Vignola AM. Airway remodelling in the pathogenesis of asthma. Curr Opin Allergy Clin Immunol 2001; 1: 85-93
20. Beckett PA, Howarth PH. Pharmacotherapy and airway remodelling in asthma? Thorax 2003; 58: 163-174
21. Walsh GM, Sexton DW, Blaylock MG. Corticosteroids, eosinophils and bronchial epithelial cells: new insights into the resolution of inflammation in asthma. J Endocrinol 2003; 178: 37-43
22. Silvestri M, Sabatini F, Scarso L, Cordone A, Dasic G, Rossi GA. Fluticasone propionate downregulates nasal fibroblast functions involved in airway inflammation and remodeling. Int Arch Allergy Immunol 2002; 128: 51-58
23. Taha Y, Carlson M, Thorn M, Loof L, Raab Y. Evidence of local eosinophil activation and altered mucosal permeability in collagenous colitis. Dig Dis Sci 2001; 46: 888-897
24. Taha Y, Raab Y, Larsson A, Carlson M, Loof L, Gerdin B, Thorn M. Vascular endothelial growth factor (VEGF) - a possible mediator of inflammation and mucosal permeability in patients with collagenous colitis. Dig Dis Sci 2004; 49: 109-115
25. Chande N, McDonald JW, Macdonald JK. Interventions for treating collagenous colitis. Cochrane Database Syst Rev 2005; 19: CD003575
26. Pardi DS. Microscopic colitis. Mayo Clin Proc 2003; 78: 614-616; quiz 616-617
27. Raab Y, Fredens K, Gerdin B, Hallgren R. Eosinophil activation in ulcerative colitis: studies on mucosal release and localization of eosinophil granule constituents. Dig Dis Sci 1998; 43: 1061-1070
28. Carlson M, Raab Y, Peterson C, Hallgren R, Venge P. Increased intraluminal release of eosinophil granule proteins EPO, ECP, EPX, and cytokines in ulcerative colitis and proctitis in segmental perfusion. Am J Gastroenterol 1999; 94: 1876-1883
29. Levy AM, Yamazaki K, Van Keulen VP, Burgart LJ, Sandborn WJ, Phillips SF, Kephart GM, Gleich GJ, Leiferman KM. Increased eosinophil infiltration and degranulation in colonic tissue from patients with collagenous colitis. Am J Gastroenterol 2001; 96: 1522-1528
30. Stahle-Backdahl M, Maim J, Veress B, Benoni C, Bruce K, Egesten A. Increased presence of eosinophilic granulocytes expressing transforming growth factor-beta1 in collagenous colitis. Scand J Gastroenterol 2000; 35: 742-746
31. Sloth H, Bisgaard C, Grove A. Collagenous colitis: a prospective trial of prednisolone in six patients. J Intern Med 1991; 229: 443-446
32. Belvisi MG. Regulation of inflammatory cell function by corticosteroids. Proc Am Thorac Soc 2004; 1: 207-214
33. Ward C, Pais M, Bish R, Reid D, Feltis B, Johns D, Walters EH. Airway inflammation, basement membrane thickening and bronchial hyperresponsiveness in asthma. Thorax 2002; 57: 309-316
34. Sangfelt P, Carlson M, Thorn M, Loof L, Raab Y. Neutrophil and eosinophil granule proteins as markers of response to local prednisolone treatment in distal ulcerative colitis and proctitis. Am J Gastroenterol 2001; 96: 1085-1090
35. Carlson M, Raab Y, Seveus L, Xu S, Hallgren R, Venge P. Human neutrophil lipocalin is a unique marker of neutrophil inflammation in ulcerative colitis and proctitis. Gut 2002; 50: 501-506
36. Raab Y, Gerdin B, Ahlstedt S, Hallgren R. Neutrophil mucosal involvement is accompanied by enhanced local production of interleukin-8 in ulcerative colitis. Gut 1993; 34: 1203-1206
37. Stampfl DA, Friedman LS. Collagenous colitis: pathophysiologic considerations. Dig Dis Sci 1991; 36: 705-711
38. Hwang WS, Kelly JK, Shaffer EA, Hershfield NB. Collagenous colitis: a disease of pericryptal fibroblast sheath? J Pathol 1986; 149: 33-40
39. Flejou JF, Grimaud JA, Molas G, Baviera E, Potet F. Collagenous colitis. Ultrastructural study and collagen immunotyping of four cases. Arch Pathol Lab Med 1984; 108: 977-982
40. Gudbjornsson B, Christofferson R, Larsson A. Synovial concentrations of the angiogenic peptides bFGF and VEGF do not discriminate rheumatoid arthritis from other forms of inflammatory arthritis. Scand J Clin Lab Invest 2004; 64: 9-15
41. Kanazawa S, Tsunoda T, Onuma E, Majima T, Kagiyama M, Kikuchi K. VEGF, basic-FGF, and TGF-beta in Crohn's disease and ulcerative colitis: a novel mechanism of chronic intestinal inflammation. Am J Gastroenterol 2001; 96: 822-828
42. Beddy D, Watson RW, Fitzpatrick JM, O'Connell PR. Increased vascular endothelial growth factor production in fibroblasts isolated from strictures in patients with Crohn's disease. Br J Surg 2004; 91: 72-77