Isolation and characterization of antibodies against three consecutive Tn-antigen clusters from a phage library displaying human single-chain variable fragments

Journal of Biochemistry

Volumn 147, Issue 6, 2010, Pages 809-817

  Sakai, Keiko ^a   Yuasa, Noriyuki ^a   Tsukamoto, Kazuhiro ^a   Takasaki Matsumoto, Ayano ^a   Yajima, Yukiko ^a   Sato, Reiko ^b   Kawakami, Hiroko ^b   Mizuno, Mamoru ^b   Takayanagi, Atsushi ^c,d   Shimizu, Nobuyoshi ^c,d   Nakata, Munehiro ^a   Fujita Yamaguchi, Yoko ^a,e  

^a TOKAI UNIVERSITY   (Japan)

^b NOGUCHI INSTITUTE   (Japan)

^c KEIO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^d KEIO UNIVERSITY   (Japan)

^e NONE   (Japan)

Author keywords

colon and breast cancer cells; human antibody; phage display; single chain Fv; Tn antigen

Indexed keywords

ANTIBODY; MONOCLONAL ANTIBODY; TN ANTIGEN;

AMINO ACID SEQUENCE; ANTIBODY ISOLATION; ARTICLE; BACTERIOPHAGE; BREAST CANCER; COLON CANCER; DNA LIBRARY; ESCHERICHIA COLI; HUMAN; HUMAN CELL; IMMUNOGLOBULIN VARIABLE REGION; NONHUMAN; SEQUENCE HOMOLOGY; SURFACE PLASMON RESONANCE;

AMINO ACID SEQUENCE; ANTIBODIES, MONOCLONAL; ANTIGENS, TUMOR-ASSOCIATED, CARBOHYDRATE; BACTERIOPHAGES; BREAST NEOPLASMS; CELL LINE, TUMOR; COLONIC NEOPLASMS; FLUORESCENT ANTIBODY TECHNIQUE; GLYCOPEPTIDES; HUMANS; IMMUNOGLOBULIN VARIABLE REGION; PEPTIDE LIBRARY; SEQUENCE HOMOLOGY, AMINO ACID; SINGLE-CHAIN ANTIBODIES; SURFACE PLASMON RESONANCE;

ESCHERICHIA COLI;

EID: 77953714330     PISSN: 0021924X     EISSN: 17562651     Source Type: Journal    
DOI: 10.1093/jb/mvq014     Document Type: Article

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