Novel approaches to global mining of aberrantly methylated promoter sites in squamous head and neck cancer

Otolaryngology - Head and Neck Surgery

Volumn 143, Issue 1, 2010, Pages

  Worsham, Maria J ^a   Chen, Kang Mei ^a   Stephen, Josena K ^a   Havard, Shaleta ^a   Benninger, Michael S ^b  

^a HENRY FORD HOSPITAL   (United States)

^b LERNER RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MARKER; GENOMIC DNA;

ARTICLE; CANCER CELL CULTURE; CANCER DIAGNOSIS; DATA BASE; DNA MICROARRAY; GENE AMPLIFICATION; HEAD AND NECK CANCER; IMMUNOPRECIPITATION; METHYLATION; PILOT STUDY; POLYMERASE CHAIN REACTION; PROMOTER REGION; QUANTITATIVE ANALYSIS; SQUAMOUS CELL CARCINOMA; TUMOR BIOPSY; TUMOR GENE;

EID: 77953668433     PISSN: 01945998     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.otohns.2010.02.015     Document Type: Article

References (24)

1. Costello J.F., and Plass C. Methylation matters. J Med Genet 38 (2001) 285-303
2. Li E., Beard C., and Jaenisch R. Role for DNA methylation in genomic imprinting. Nature 366 (1993) 362-365
3. Pfeifer G.P., Tanguay R.L., Steigerwald S.D., et al. In vivo footprint and methylation analysis by PCR-aided genomic sequencing: comparison of active and inactive X chromosomal DNA at the CpG island and promoter of human PGK-1. Genes Dev 4 (1990) 1277-1287
4. Costello J.F., Fruhwald M.C., Smiraglia D.J., et al. Aberrant CpG-island methylation has non-random and tumour-type-specific patterns. Nat Genet 24 (2000) 132-138
5. Smiraglia D.J., Smith L.T., Lang J.C., et al. Differential targets of CpG island hypermethylation in primary and metastatic head and neck squamous cell carcinoma (HNSCC). J Med Genet 40 (2003) 25-33
6. Jones P.A., and Laird P.W. Cancer epigenetics comes of age. Nat Genet 21 (1999) 163-167
7. Cairns P. Detection of promoter hypermethylation of tumor suppressor genes in urine from kidney cancer patients. Ann N Y Acad Sci 1022 (2004) 40-43
8. Worsham M.J., Pals G., Schouten J.P., et al. Delineating genetic pathways of disease progression in head and neck squamous cell carcinoma. Arch Otolaryngol Head Neck Surg 129 (2003) 702-708
9. Worsham M.J., Chen K.M., Tiwari N., et al. Fine-mapping loss of gene architecture at the CDKN2B (p15INK4b), CDKN2A (p14ARF, p16INK4a), and MTAP genes in head and neck squamous cell carcinoma. Arch Otolaryngol Head Neck Surg 132 (2006) 409-415
10. Sanchez-Cespedes M., Okami K., Cairns P., et al. Molecular analysis of the candidate tumor suppressor gene ING1 in human head and neck tumors with 13q deletions. Genes Chromosomes Cancer 27 (2000) 319-322
11. Maruya S., Issa J.P., Weber R.S., et al. Differential methylation status of tumor-associated genes in head and neck squamous carcinoma: incidence and potential implications. Clin Cancer Res 10 (2004) 3825-3830
12. Worsham M.J., Chen K.M., Meduri V., et al. Epigenetic events of disease progression in head and neck squamous cell carcinoma. Arch Otolaryngol Head Neck Surg 132 (2006) 668-677
13. Worsham M.J., Wolman S.R., Carey T.E., et al. Chromosomal aberrations identified in culture of squamous carcinomas are confirmed by fluorescence in situ hybridisation. Mol Pathol 52 (1999) 42-46
14. Ongenaert M., Van Neste L., De Meyer T., et al. PubMeth: a cancer methylation database combining text-mining and expert annotation. Nucleic Acids Res 36 (2008) D842-D846
15. Jemal A., Siegel R., Ward E., et al. Cancer statistics, 2009. CA Cancer J Clin 59 (2009) 225-249
16. Edwards B.K., Brown M.L., Wingo P.A., et al. Annual report to the nation on the status of cancer, 1975-2002, featuring population-based trends in cancer treatment. J Natl Cancer Inst 97 (2005) 1407-1427
17. Esteller M., Corn P.G., Baylin S.B., et al. A gene hypermethylation profile of human cancer. Cancer Res 61 (2001) 3225-3229
18. Chen K., Sawhney R., Khan M., et al. Methylation of multiple genes as diagnostic and therapeutic markers in primary head and neck squamous cell carcinoma. Arch Otolaryngol Head Neck Surg 133 (2007) 1131-1138
19. Pegg A.E. Mammalian O6-alkylguanine-DNA alkyltransferase: regulation and importance in response to alkylating carcinogenic and therapeutic agents. Cancer Res 50 (1990) 6119-6129
20. Hirohashi S. Inactivation of the E-cadherin-mediated cell adhesion system in human cancers. Am J Pathol 153 (1998) 333-339
21. Stephen J.K., Vaught L.E., Chen K.M., et al. Epigenetic events underlie the pathogenesis of sinonasal papillomas. Mod Pathol 20 (2007) 1019-1027
22. Stephen J.K., Vaught L.E., Chen K.M., et al. An epigenetically derived monoclonal origin for recurrent respiratory papillomatosis. Arch Otolaryngol Head Neck Surg 133 (2007) 684-692
23. Fliss M.S., Usadel H., Caballero O.L., et al. Facile detection of mitochondrial DNA mutations in tumors and bodily fluids. Science 287 (2000) 2017-2019
24. Sanchez-Cespedes M., Esteller M., Wu L., et al. Gene promoter hypermethylation in tumors and serum of head and neck cancer patients. Cancer Res 60 (2000) 892-895