Urinary Connective Tissue Growth Factor Is a Biomarker in a Rat Model of Chronic Nephropathy

Transplantation Proceedings

Volumn 42, Issue 5, 2010, Pages 1875-1880

  Yue, L ^a   Xia, Q ^a   Luo, G H ^a   Lu, Y P ^a  

^a SICHUAN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CONNECTIVE TISSUE GROWTH FACTOR; CREATININE;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CHRONIC ALLOGRAFT NEPHROPATHY; CONTROLLED STUDY; CREATININE BLOOD LEVEL; ENZYME LINKED IMMUNOSORBENT ASSAY; KIDNEY; MALE; MORPHOLOGY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; URINE LEVEL; WESTERN BLOTTING;

ANIMALS; BIOLOGICAL MARKERS; BLOTTING, WESTERN; CONNECTIVE TISSUE GROWTH FACTOR; CREATININE; DNA PRIMERS; KIDNEY DISEASES; KIDNEY TRANSPLANTATION; MALE; RATS; RATS, INBRED F344; RATS, INBRED LEW; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA; RNA, MESSENGER; TRANSPLANTATION, HOMOLOGOUS;

EID: 77953667081     PISSN: 00411345     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.transproceed.2009.11.041     Document Type: Article

References (24)

1. Nankivell B.J., Borrows R.J., Fung C.L., et al. The natural history of chronic allograft nephropathy. N Engl J Med 349 (2003) 2326
2. Meyers C.M., and Krik A.D. Workshop on late renal allograft dysfunction. Am J Trnasplant 5 (2005) 1600
3. Racusen L.C., Solez K., Colvin R.B., et al. The Banff97 working classification of renal allograft pathology. Kidney Int 55 (1999) 713
4. Schwarz A., Mengel M., Gwinner W., et al. Risk factors for chronic allograft nephropathy after renal transplantation: a protocol biopsy study. Kidney Int 67 (2005) 341
5. Li B., Hartono C., Ding R., et al. Noninvasive diagnosis of renal-allograft rejection by measurement of messenger RNA for perforin and granzyme B in urine. N Engl J Med 344 (2001) 947
6. Hauser I.A., Spiegler S., Kiss E., et al. Prediction of acute renal allograft rejection by urinary monokine induced by IFN-gamma (MIG). J Am Soc Nephrol 16 (2005) 1849
7. Shi Y., Tu Z., Wang W., et al. Homologous peptide of connective tissue growth factor ameliorates epithelial to mesenchymal transition of tubular epithelial cells. Cytokine 36 (2006) 35
8. Cheng O., Thuillier R., Sampson E., et al. Connective tissue growth factor is a biomarker and mediator of kidney allograft fibrosis. Am J Transplant 6 (2006) 2292
9. Kamada N. A description of cuff techniques for renal transplantation in the rat. Use in studies of tolerance induction during combined liver grafting. Transplantation 39 (1985) 93
10. Tamatani T., Kobayashi H., Tezuka K., et al. Establishment of the enzyme-linked immunosorbent assay for connective tissue growth factor (CTGF) and its detection in the sera of biliary atresia. Biochem Biophys Res Commun 251 (1998) 748
11. Nankivell B.I., and Chapman J.R. Chronic allograft nephropathy: current concepts and future directions. Transplantation 81 (2006) 643
12. Pascual M., Theruvath T., Kawai T., Tolkoff-Rubin N., and Cosimi A.B. Strategies to improve long-term outcomes after renal transplantation. N Engl J Med 346 (2002) 580-590
13. Knight R.J., Burrows L., and Bodian C. The influence of acute rejection on long-term renal allograft survival: a comparison of living and cadaveric donor transplantation. Transplantation 72 (2001) 69
14. Moreso F., Lopez M., Vallejos A., et al. Serial protocol biopsies to quantify the progreesion of chronic transplant nephropathy in stable renal allografts. Am J Transplant 1 (2001) 82
15. Furness P.N., Philpott C.M., Chorbadjian M.T., et al. Protocol biopsy of the stable renal transplant: a multicenter study of methods and complication rates. Transplantation 76 (2003) 969
16. Hu H. Elevation of multiple cytokines/chemokines in urine of human renal transplant recipients with actue and chronic injuries: potential usage for diagnosis and monitoring. Transplant Rev 20 (2006) 165
17. Vongiwiwatana A., Tasanarong A., Rayner D.C., et al. Epithelial to mesenchymal transition during late deterioration of human kidney transplants: the role of tubular cells in fibrogenesis. Am J Transplant 5 (2005) 1367
18. Tyler J.R., Robertson H., Booth T.A., et al. Chronic allograft nephropathy: intraepithelial signals generated by transforming growth factor-beta and bone morphogenetic protein-7. Am J Transplant 6 (2006) 1367
19. Tu Z., Shi Y., Wang J., et al. Upregulation of connective tissue growth factor in a rat model of chronic allograft nephropathy. Nephrology (Cartlon) 12 (2007) 166
20. Gao R., Lu Y., Xin Y.P., et al. The effects of different immunosuppressants on chronic allograft nephropathy by affecting the transforming growth factor-beta and Smads signal pathways. Transplant Proc 38 (2006) 2154
21. Grotendorst G.R., and Duncan M.R. Individual domains of connective tissue growth factor regulate fibroblast proliferation and myofibroblast differentiation. FASEB J 19 (2005) 729
22. Nguyen T.Q., Tarnow L., Anderson S., et al. Urinary connective tissue growth factor excretion correlates with clinical markers of renal disease in a large population of type 1 diabetic patients with diabetic nephropathy. Diabetes Care 29 (2006) 83
23. Thomson S.E., McLennan S.V., and Kirwan P.D. Renal connective tissue growth factor correlated with glomerular basement membrane thickness and prospective albuminuria in a non-human primate model of diabetes: possible predictive marker for incipient diabetic nephropathy. J Diabetes Complication 22 (2008) 284
24. Helantera I., Teppo A.M., Koskinen P., et al. Increased urinary excretion of transforming growth factor-beta(1) in renal transplant recipients during cytomegalovirus infection. Transpl Immunol 15 (2006) 217