Benzylcarbamothioethionate from root bark of Moringa oleifera Lam. and its toxicological evaluation;Bencilcarbamotioetionato de la raíz de Moringa oleifera Lam. y su evaluación toxicológica

Boletin Latinoamericano y del Caribe de Plantas Medicinales y Aromaticas

Volumn 8, Issue 2, 2009, Pages 130-138

  Nikkon, Farjana ^a   Hasan, Sohel ^a   Salam, Kazi Abdus ^a   Mosaddik, Mohammed A ^b   Khondkar, Proma ^b   Haque, Mohammed Ekramul ^b   Rahman, Mukhlesur ^c  

^a Department of Biochemistry and Molecular Biology   (Bangladesh)

^b UNIVERSITY OF RAJSHAHI   (Bangladesh)

^c UNIVERSITY OF LONDON   (United Kingdom)

Author keywords

Benzylcarbamothioethionate; toxicity; Moringa oleifera; Moringaceae

Indexed keywords

ALANINE AMINOTRANSFERASE; ALKALINE PHOSPHATASE; ASPARTATE AMINOTRANSFERASE; BENZYLCARBAMOTHIOETHIONATE; BILIRUBIN; CHLOROFORM; CREATININE; HEMOGLOBIN; THIOCARBAMIC ACID DERIVATIVE; UNCLASSIFIED DRUG; UREA;

ACUTE TOXICITY; ALANINE AMINOTRANSFERASE BLOOD LEVEL; ALKALINE PHOSPHATASE BLOOD LEVEL; ANIMAL EXPERIMENT; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; BARK; BILIRUBIN BLOOD LEVEL; BLOOD SAMPLING; CHEMICAL ANALYSIS; CONTROLLED STUDY; CREATININE BLOOD LEVEL; CRYSTAL STRUCTURE; ERYTHROCYTE; ERYTHROCYTE COUNT; ERYTHROCYTE SEDIMENTATION RATE; FRACTIONATION; HEART; HEMATOLOGICAL PARAMETERS; HISTOPATHOLOGY; KIDNEY; LEUKOCYTE; LEUKOCYTE DIFFERENTIAL COUNT; LIVER; LUNG; MASS SPECTROMETRY; MEDICINAL PLANT; MORINGA OLEIFERA; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PLANT ROOT; RAT; THROMBOCYTE COUNT; TOXICOLOGICAL PARAMETERS; UREA BLOOD LEVEL;

MORINGA OLEIFERA; MORINGACEAE; RATTUS;

EID: 77953646302     PISSN: None     EISSN: 07177917     Source Type: Journal    
DOI: None     Document Type: Article

References (38)

1. Abdulkarim SM, Long K, Lai OM, Muhammad SKS, Ghazali HM. 2005. Some physico-chemical properties of Moringa oleifera seed oil extracted using solvent and aqueous enzymatic methods. Food Chem 93:253-263.
2. Ahmed M, Rashid MA, Choudhury SAR, Choudhury AKA. 1986. Hypotensive effect of methanol extract of Moringa oleifera in rats. Bangladesh J Physiol Pharmacol 4:27-32.
3. Bennett RN, Mellon FA, Nikolaus F, John PH, Susan DM, Lionel P, Paul KA. 2003. Profiling glucosinolates and phenolics in vegetative and productive tissues of the multipurpose trees Moringa oleifera L. (horseradish tree) and Moringa stenopetala L. J Agric Food Chem 51:3546-3553.
4. Caceres A, Alvarez AV, Freire V, Giron LM, Pacheco JG. 1991. Pharmacological properties of Moringa oleifera: Preliminary screening for antimicrobial activity. Economic Bot 45:522-526.
5. Cáceres A, Saravia A, Rizzo S, Zabala L, Leon ED, Nave F. 1992. Pharmacological Properties of Moringa oleifera: Screening for antipasmodic, antiinflammatory and diuretic activity. J Ethnopharmacol 36:233-237.
6. Ching LS, Mohamed S. 2001. Alpha-tocopherol content in 62 edible tropical plants. J Agric Food Chem 49:3101-3105.
7. Chopra RN. 1958. Indigenous drugs of India. U.N. Dhar and sons (pvt.) Ltd., Calcutta, p 364.
8. Ezeamuzie IC, Ambakederemo AW, Shode FO, Ekwebelem SC. 1996. Antiinflammatory effects of Moringa oleifera root extract. Int J Pharmacog 34:207-212.
9. Faizi S, Siddiqui BS, Saleem R, Aftab K, Shaheen F, Gilani AH. 1998. Hypotensive constituents from the pods of Moringa oleifera. Planta Med 64:225-228.
10. Faizi S, Siddiqui BS, Saleem R, Noor F, Husnain S. 1997. Isolation and structure elucidation of a novel glycoside niazidin from the pods of Moringa oleifera. J Nat Prod 60:1317-1321.
11. Faizi S, Siddiqui BS, Saleem R, Siddiqui S, Aftab K, Gilani AUH. 1995. Fully acetylated carbamate and hypotensive thiocarbamate glycosides from Moringa oleifera. Phytochemistry 38:957-963.
12. Farooq A, Bhanger MI. 2003. Analytical characterization of Moringa oleifera seed oil grown in temperate regions of Pakistan. J Agric Food Chem 51:6558-6563.
13. Francis JA, Bolleddula J, Olson LK, Muraleedharan NG. 2004. Insulin secretagogues from Moringa oleifera with cyclooxygenase enzyme and lipid peroxidation inhibitory activities. Helv Chim Acta 87:317-326.
14. Gaur E. 1962. Staining, Animal Tissues, Leonard Hill (Books) Ltd. London, p 631.
15. 13C NMR characterization of triacylglycerols of Moringa oleifera seed oil: An "oleic-vaccenic acid" oil. J Agric Food Chem 50:970-975.
16. Guevara AP, Vargas C, Sakurai H, Fujiwara Y, Hashimoto K, Maoka T, Kozuka M, Ito Y, Tokuda H, Nishino H. 1999. An antitumor promoter from Moringa oleifera Lam. Mutat Res 440:181-188.
17. Gupta M, Mazumder UK, Chakrabarti S. 1999. CNS activities of methanolic extract of Moringa oleifera root in mice. Fitoterapia 70:244-250.
18. th edn., McGraw Hill Book Company, USA. pp 136-139.
19. Kausik R, Rimi H, Debjani G. 2003. Central inhibitory effect of Moringa oleifera root extract: possible role of neurotransmitters. Indian J Exp Biol 41:1279-1284.
20. Kirtikar KR, Basu K. 1984. Indian Medicinal Plants. Lalit Mohan Basu MB. Allahabad, India, vol. 1, pp 677-680.
21. Kurup PA, Rao KL. 1954. An antibiotic substance, pterygospermin from the root of Moringa oleifera. Indian J Med Res 42:85-88.
22. Lucy H, Edgar JD. 1999. Medicinal plants: a re-emerging health aid. Electronic J Biotechnol 2:1-15.
23. Mahajan SG, Mehta AA. 2007. Inhibitory action of ethanolic extract of seeds of Moringa oleifera on systemic and local anaphylaxis. J Immunotoxicol 4:287-294.
24. Mazumder UK, Gupta M, Chakrabarti S, Pal D. 1999. Evaluation of hematological and hepatorenal functions of methanolic extract of Moringa olefera Lam. root treated mice. Indian J Exp Biol 37:612-614.
25. Murakami A, Kitazono Y, Jiwajinda S. 1998. Niaziminin, a thiocarbamate from the leaves of Moringa oleifera, holds a strict structural requirement for inhibition of tumor-promotor induced Epstein-Barr virus activation. Planta Med 64:319-323.
26. Olfert ED, Cross BM, McWillian AA. 1993. Guide to the Care and Use of Experimental Animals. Canadian Council on Animal Care, Ottawa, Ontario.
27. Prakash AR. 1988. Ovarian response to aqueous extract of Moringa oleifera during early pregnancy in rats. Fitoterapia 59:89-96.
28. Ramiah N, Nair GN. 1977. Amino acid and sugars in the flowers and fruits of Moringa oleifera Lam. J Instn Chem 49:163.
29. Rangaswamy L, Marisiddaiah R, Parthasarathy KT, Vallikannan B. 2005. Determination of major carotenoids in a few Indian leafy vegetables by high performance liquid chromatography. J Agric Food Chem 53:2838-2842.
30. Saluja MP, Kapil RS, Popli SP. 1978. Studies on Medicinal Plants. Part vi. Chemical constituents of Moringa oleifera Lam. (hybrid variety) and isolation of 4-hydroxymellein. Indian J Chem 16:1044.
31. Santos AFS, Argolo ACC, Coelho LCBB, Paiva PMG. 2005. Detection of water soluble lectin and antioxidant component from Moringa oleifera seeds. Water Res 39: 975-980.
32. Sastri BN. 1962. The wealth of India. Council of Scientific and Industrial Research, New Delhi. p 425.
33. rd (ed), Wadsworth Publication Co. Inc., Belmont, California.
34. Shukla S, Mathur R, Prakash AO. 1988. Antifertility profile of the aqueous extract of Moringa oleifera roots. J Ethnopharmacol 22:51-62.
35. Siddhuraju P, Becker K. 2003. Antioxidant properties of various solvent extracts of total phenolic constituents from three different agroclimatic origins of drumstick tree (Moringa oleifera Lam.) leaves. J Agric Food Chem 51:2144-2155.
36. Stavros L, John T. 2002. Extraction and identification of natural antioxidant from the seeds of the Moringa oleifera tree variety of Malawi. J Am Oil Chem Soc 79:677-683.
37. UNESCO. 1996. Culture and Health, Orientation Texts World Decade for Cultural Development 1988-1997. Documents CLT/DEC. PRO-1996, Paris, France, p 129.
38. Yusuf M, Chowdhury JU, Wahab MA, Begum J. 1994. Medicinal plants of Bangladesh, BCSIR Laboratories, Chittagong, Bangladesh, p 171.