Computer simulations from a finite-element model for wound contraction and closure

Journal of Tissue Viability

Volumn 19, Issue 2, 2010, Pages 43-53

  Vermolen, F J ^a,b   Javierre, E ^b  

^a DELFT UNIVERSITY OF TECHNOLOGY   (Netherlands)

^b UNIVERSITY OF ZARAGOZA   (Spain)

Author keywords

Angiogenesis; Finite element method; Wound closure; Wound contraction; Wound healing

Indexed keywords

GROWTH FACTOR; HORMONE;

ANGIOGENESIS; ARTICLE; CELL MIGRATION; CELL TYPE; COMPUTER SIMULATION; ENDOTHELIUM CELL; EPITHELIUM CELL; FINITE ELEMENT ANALYSIS; GEOMETRY; HUMAN; PRIORITY JOURNAL; WOUND CARE; WOUND CLOSURE; WOUND CONTRACTION; WOUND HEALING; BIOLOGICAL MODEL; PHYSIOLOGY;

COMPUTER SIMULATION; FINITE ELEMENT ANALYSIS; HUMANS; MODELS, BIOLOGICAL; NEOVASCULARIZATION, PHYSIOLOGIC; WOUND HEALING;

EID: 77953630334     PISSN: 0965206X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jtv.2009.11.003     Document Type: Article

References (25)

1. H.N. Paddock, G.S. Schultz, and B.A. Mast Methods in reepithalization L.A. DiPietro, A.I. Burns, Wound healing methods and protocols 2003 Humana Press Inc. Totowa, New Jersey, USA
2. J.A. Sherratt, and J.D. Murray Mathematical analysis of a basic model for epidermal wound healing J Math Biol 29 1991 389 404
3. P.H. Lambert, and P.E. Laurent Intradermal vaccine delivery: will new delivery systems transform vaccine administration? Vaccine 26 26 2008 3197 3208
4. E.A. Gaffney, K. Pugh, and P.K. Maini Investigating a simple model for cutaneous wound healing angiogenesis J Math Biol 45 4 2002 337 374
5. M.J. Plank, and B.D. Sleeman A reinforced random walk model of tumour angiogenesis and anti-angiogenic strategies Math Med Biol 20 2003 135 181
6. M.J. Plank, and B.D. Sleeman Lattice and non-lattice models of tumour angiogenesis Bull Mathem Biol 66 2004 1785 1819
7. J.D. Murray Mathematical biology II: spatial models and biomedical applications 2004 Springer-Verlag New York
8. S.A. Maggelakis Modeling the role of angiogenesis in epidermal wound healing Discr Cont Sys 4 2004 267 273
9. F.J. Vermolen, and J.A. Adam A finite element model for epidermal wound healing Computational science, ICCS 2007 2007 Springer Berlin - Heidelberg, Germany 70 77
10. Vermolen FJ, Javierre E. A suite of continuum models for different aspects in wound healing. In: Bioengineering research of chronic wounds, studies in mechanobiology, tissue engineering and biomaterials. Springer; in press.
11. Vermolen FJ, Javierre E. A simplified finite-element model for wound contraction and closure; in press.
12. W.K. Stadelman, A.G. Digenis, and G.R. Tobin Physiology and healing dynamics of chronic cutaneous wounds Am J Surg 176 2 1997 26S 38S
13. L. Olsen, J.A. Sherratt, and P.K. Maini A mechanochemical model for adult dermal wound closure and the permanence of the contracted tissue displacement role J Theor Biol 177 1995 113 128
14. J.D. Murray On the mechanochemical theory of biological pattern formation with application to vasculogenesis C R Biol 326 2003 239 252
15. H.J. Wearing, and J.D. Sherratt Keratinocyte growth factor signalling: a mathematical model of dermal-epidermal interaction in epidermal wound healing Math Biosci 165 2000 41 62
16. H. Rossiter, C. Barresi, J. Pammer, M. Rendl, J. Haigh, and E.F. Wagner Loss of vascular endothelial growth factor A activity in murine epidermal keratinocytes delays wound healing and inhibits tumor formation Cancer Res 64 2004 3508 3516
17. Alarcon T, Byrne H, Maini P, Panovska J. Mathematical modeling of angiogenesis and vascular adaptation. In: Paton R, McNamara, L, editors. Studies in multidisciplinary, vol. 3; 2006. p. 369-87.
18. F.J. Vermolen A simplified finite element model for tissue regeneration with angiogenesis ASCE J Eng Mechanics 135 5 2008 2009
19. Lamme EN. Artificial skin and tissue regeneration, thesis. The University of Amsterdam, the Netherlands; 1999.
20. R.E. Friesel, and T. Maciang Molecular mechanisms of angiogenesis: fibroblast growth factor signal transduction FASEB J 9 1995 919 925
21. K.V. Stoletov, K.E. Ratcliffe, and B.I. Terman Fibroblast growth factor receptor substrate 2 participates in vascular endothelial growth factor-induced signaling FASEB J 16 2002 1283 1285
22. R.T. Tranquillo, and J.D. Murray Continuum model of fibroblast-driven wound contraction inflammation-mediation J Theor Biol 158 2 1992 135 172
23. G.J. Pettet, H.M. Byrne, D.L.S. McElwain, and J. Norbury A model of wound healing angiogenesis in soft tissue Math Biosci 136 1996 35 63
24. A.F. Laplante, L. Germain, F.A. Auger, and V. Moulin Mechanisms of wound reepithelialization: hints from a tissue-engineered reconstructed skin to long-standing questions FASEB J 15 2001 2377 2382
25. M.J. Escámez, M. García, F. Larcher, A. Meana, E. Nuñoz, and J.L. Jorcano An in vivo model of wound healing in genetically modified skin-humanized mice J Invest Dermatol 123 2004 1182 1191