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Volumn 34, Issue 8, 2010, Pages 991-994

Aberrant methylation of DNA-damage-inducible transcript 3 promoter is a common event in patients with myelodysplastic syndrome

Author keywords

DDIT3 gene; Methylation; Myelodysplastic syndrome

Indexed keywords

GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153;

EID: 77953611367     PISSN: 01452126     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.leukres.2010.01.003     Document Type: Article
Times cited : (10)

References (35)
  • 1
    • 34249786233 scopus 로고    scopus 로고
    • Definitions and standards in the diagnosis and treatment of the myelodysplastic syndromes: consensus statements and report from a working conference
    • Valent P., Horney H.P., Bennett J.M., Fonatsch C., Germing U., Greenberg P., et al. Definitions and standards in the diagnosis and treatment of the myelodysplastic syndromes: consensus statements and report from a working conference. Leuk Res 2007, 31:727-736.
    • (2007) Leuk Res , vol.31 , pp. 727-736
    • Valent, P.1    Horney, H.P.2    Bennett, J.M.3    Fonatsch, C.4    Germing, U.5    Greenberg, P.6
  • 2
    • 1842833239 scopus 로고    scopus 로고
    • Molecular pathogenesis of MDS
    • Hirai H. Molecular pathogenesis of MDS. Int J Hematol 2002, 76:213-221.
    • (2002) Int J Hematol , vol.76 , pp. 213-221
    • Hirai, H.1
  • 3
    • 0034551738 scopus 로고    scopus 로고
    • The role of apoptosis, proliferation, and the Bcl-2-related proteins in the myelodysplastic syndromes and acute myeloid leukemia secondary to MDS
    • Parker J.E., Mufti G.J., Rasool F., Mijovic A., Devereux S., Pagliuca A. The role of apoptosis, proliferation, and the Bcl-2-related proteins in the myelodysplastic syndromes and acute myeloid leukemia secondary to MDS. Blood 2000, 96:3928-3932.
    • (2000) Blood , vol.96 , pp. 3928-3932
    • Parker, J.E.1    Mufti, G.J.2    Rasool, F.3    Mijovic, A.4    Devereux, S.5    Pagliuca, A.6
  • 4
    • 35448934364 scopus 로고    scopus 로고
    • Apoptosis and antiapoptotic mechanisms in the progression of myelodysplastic syndrome
    • Kerbauy D.B., Deeg H.J. Apoptosis and antiapoptotic mechanisms in the progression of myelodysplastic syndrome. Exp Hematol 2007, 35:1739-1746.
    • (2007) Exp Hematol , vol.35 , pp. 1739-1746
    • Kerbauy, D.B.1    Deeg, H.J.2
  • 5
    • 0036720398 scopus 로고    scopus 로고
    • The roles of FLT3 in hematopoiesis and leukemia
    • Gilliland D.G., Griffin J.D. The roles of FLT3 in hematopoiesis and leukemia. Blood 2002, 100:1532-1542.
    • (2002) Blood , vol.100 , pp. 1532-1542
    • Gilliland, D.G.1    Griffin, J.D.2
  • 6
    • 33847790838 scopus 로고    scopus 로고
    • Genetic abnormalities as targets for molecular therapies in myelodysplastic syndromes
    • Cilloni D., Messa E., Messa F., Carturan S., Defilippi I., Arruga F., et al. Genetic abnormalities as targets for molecular therapies in myelodysplastic syndromes. Ann N Y Acad Sci 2006, 1089:411-423.
    • (2006) Ann N Y Acad Sci , vol.1089 , pp. 411-423
    • Cilloni, D.1    Messa, E.2    Messa, F.3    Carturan, S.4    Defilippi, I.5    Arruga, F.6
  • 8
    • 33749185394 scopus 로고    scopus 로고
    • SALL4, a novel oncogene, is constitutively expressed in human acute myeloid leukemia (AML) and induces AML in transgenic mice
    • Ma Y., Cui W., Yang J., Qu J., Di C., Amin H.M., et al. SALL4, a novel oncogene, is constitutively expressed in human acute myeloid leukemia (AML) and induces AML in transgenic mice. Blood 2006, 15:2726-2735.
    • (2006) Blood , vol.15 , pp. 2726-2735
    • Ma, Y.1    Cui, W.2    Yang, J.3    Qu, J.4    Di, C.5    Amin, H.M.6
  • 9
    • 10344260184 scopus 로고    scopus 로고
    • CpG island methylator phenotype in cancer
    • Issa J.P. CpG island methylator phenotype in cancer. Nat Rev Cancer 2004, 4:988-993.
    • (2004) Nat Rev Cancer , vol.4 , pp. 988-993
    • Issa, J.P.1
  • 10
    • 33947315736 scopus 로고    scopus 로고
    • Cancer epigenomics: DNA methylomes and histone-modification maps
    • Esteller M. Cancer epigenomics: DNA methylomes and histone-modification maps. Nat Rev Genetics 2007, 8:286-298.
    • (2007) Nat Rev Genetics , vol.8 , pp. 286-298
    • Esteller, M.1
  • 11
    • 34249982046 scopus 로고    scopus 로고
    • Gene silencing by DNA methylation in haematological malignancies
    • Boultwood J., Wainscoat J.S. Gene silencing by DNA methylation in haematological malignancies. Br J Haematol 2007, 138:3-11.
    • (2007) Br J Haematol , vol.138 , pp. 3-11
    • Boultwood, J.1    Wainscoat, J.S.2
  • 12
    • 0942276838 scopus 로고    scopus 로고
    • Aberrant methylation of DAP-kinase in therapy-related acute myeloid leukemia and myelodysplastic syndromes
    • Voso M.T., Scardocci A., Guidi F., Zini G., Di Mario A., Pagano L., et al. Aberrant methylation of DAP-kinase in therapy-related acute myeloid leukemia and myelodysplastic syndromes. Blood 2004, 103:698-700.
    • (2004) Blood , vol.103 , pp. 698-700
    • Voso, M.T.1    Scardocci, A.2    Guidi, F.3    Zini, G.4    Di Mario, A.5    Pagano, L.6
  • 13
    • 33644878393 scopus 로고    scopus 로고
    • Promoter hypermethylation of p15INK4B, HIC1, CDH1, and ER is frequent in myelodysplastic syndrome and predicts poor prognosis in early-stage patients
    • Aggerholm A., Holm M.S., Guldberg P., Olesen L.H., Hokland P. Promoter hypermethylation of p15INK4B, HIC1, CDH1, and ER is frequent in myelodysplastic syndrome and predicts poor prognosis in early-stage patients. Eur J Haematol 2006, 76:23-32.
    • (2006) Eur J Haematol , vol.76 , pp. 23-32
    • Aggerholm, A.1    Holm, M.S.2    Guldberg, P.3    Olesen, L.H.4    Hokland, P.5
  • 14
    • 44749094151 scopus 로고    scopus 로고
    • Methylation status of fragile histidine triad (FHIT) gene and its clinical impact on prognosis of patients with myelodysplastic syndrome
    • Lin L., Yao D.M., Qian J., Wang Y.L., Han L.X., Jiang Y.W., et al. Methylation status of fragile histidine triad (FHIT) gene and its clinical impact on prognosis of patients with myelodysplastic syndrome. Leuk Res 2008, 32:1541-1545.
    • (2008) Leuk Res , vol.32 , pp. 1541-1545
    • Lin, L.1    Yao, D.M.2    Qian, J.3    Wang, Y.L.4    Han, L.X.5    Jiang, Y.W.6
  • 16
    • 0026546365 scopus 로고
    • CHOP, a novel developmentally regulated nuclear protein that dimerizes with transcription factors C/EBP and LAP and functions as a dominant-negative inhibitor of gene transcription
    • Ron D., Habener J.F. CHOP, a novel developmentally regulated nuclear protein that dimerizes with transcription factors C/EBP and LAP and functions as a dominant-negative inhibitor of gene transcription. Genes Dev 1992, 6:439-453.
    • (1992) Genes Dev , vol.6 , pp. 439-453
    • Ron, D.1    Habener, J.F.2
  • 17
    • 0024990364 scopus 로고
    • Isolation and characterization of the hamster gadd153 gene. Activation of promoter activity by agents that damage DNA
    • Luethy J.D., Fargnoli J., Park J.S., Fornace A.J., Holbrook N.J. Isolation and characterization of the hamster gadd153 gene. Activation of promoter activity by agents that damage DNA. J Biol Chem 1990, 165:16521-16526.
    • (1990) J Biol Chem , vol.165 , pp. 16521-16526
    • Luethy, J.D.1    Fargnoli, J.2    Park, J.S.3    Fornace, A.J.4    Holbrook, N.J.5
  • 18
    • 0026546246 scopus 로고
    • Activation of the gadd153 promoter by genotoxic agents: a rapid and specific response to DNA damage
    • Luethy J.D., Holbrook N.J. Activation of the gadd153 promoter by genotoxic agents: a rapid and specific response to DNA damage. Cancer Res 1992, 52:5-10.
    • (1992) Cancer Res , vol.52 , pp. 5-10
    • Luethy, J.D.1    Holbrook, N.J.2
  • 19
    • 0032054744 scopus 로고    scopus 로고
    • CHOP is implicated in programmed cell death in response to impaired function of the endoplasmic reticulum
    • Zinszner H., Kuroda M., Wang X., Batchvarova N., Lightfoot R.T., Remotti H., et al. CHOP is implicated in programmed cell death in response to impaired function of the endoplasmic reticulum. Genes Dev 1998, 12:982-995.
    • (1998) Genes Dev , vol.12 , pp. 982-995
    • Zinszner, H.1    Kuroda, M.2    Wang, X.3    Batchvarova, N.4    Lightfoot, R.T.5    Remotti, H.6
  • 20
    • 27644583909 scopus 로고    scopus 로고
    • Decreased expression of CCAAT/enhancer binding protein zeta (C/EBPzeta) in patients with different myeloid diseases
    • Qian J., Chen Z., Lin J., Wang W., Cen J. Decreased expression of CCAAT/enhancer binding protein zeta (C/EBPzeta) in patients with different myeloid diseases. Leuk Res 2005, 29:1435-1441.
    • (2005) Leuk Res , vol.29 , pp. 1435-1441
    • Qian, J.1    Chen, Z.2    Lin, J.3    Wang, W.4    Cen, J.5
  • 22
    • 0036786901 scopus 로고    scopus 로고
    • The World Health Organization (WHO) classification of the myeloid neoplasms
    • Vardiman J.W., Harris N.L., Brunning R.D. The World Health Organization (WHO) classification of the myeloid neoplasms. Blood 2002, 100:2292-2302.
    • (2002) Blood , vol.100 , pp. 2292-2302
    • Vardiman, J.W.1    Harris, N.L.2    Brunning, R.D.3
  • 23
    • 0030897009 scopus 로고    scopus 로고
    • International scoring system for evaluating prognosis in myelodysplastic syndromes
    • [Erratum in: Blood 91 (1998), p. 1100]
    • Greenberg P., Cox C., LeBeau M.M., Fenaux P., Morel P., Sanz G., et al. International scoring system for evaluating prognosis in myelodysplastic syndromes. Blood 1997, 89:2079-2088. [Erratum in: Blood 91 (1998), p. 1100].
    • (1997) Blood , vol.89 , pp. 2079-2088
    • Greenberg, P.1    Cox, C.2    LeBeau, M.M.3    Fenaux, P.4    Morel, P.5    Sanz, G.6
  • 24
    • 0035992304 scopus 로고    scopus 로고
    • Gene expression profiling in chronic myeloid leukemia patients treated with hydroxyurea
    • Bruchova H., Borovanova T., Klamova H., Brdicka R. Gene expression profiling in chronic myeloid leukemia patients treated with hydroxyurea. Leuk Lymphoma 2002, 43:1289-1295.
    • (2002) Leuk Lymphoma , vol.43 , pp. 1289-1295
    • Bruchova, H.1    Borovanova, T.2    Klamova, H.3    Brdicka, R.4
  • 25
    • 0035845568 scopus 로고    scopus 로고
    • Nitric oxide-induced apoptosis in pancreatic beta cells is mediated by the endoplasmic reticulum stress pathway
    • Oyadomari S., Takeda K., Takiguchi M., Gotoh T., Matsumoto M., Wada I., et al. Nitric oxide-induced apoptosis in pancreatic beta cells is mediated by the endoplasmic reticulum stress pathway. Proc Natl Acad Sci USA 2001, 98:10845-10850.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 10845-10850
    • Oyadomari, S.1    Takeda, K.2    Takiguchi, M.3    Gotoh, T.4    Matsumoto, M.5    Wada, I.6
  • 26
    • 33749244450 scopus 로고    scopus 로고
    • Clinical implications of SOCS1 methylation in myelodysplastic syndrome
    • Wu S.J., Yao M., Chou W.C., Tang J.L., Chen C.Y., Ko B.S., et al. Clinical implications of SOCS1 methylation in myelodysplastic syndrome. Br J Haematol 2006, 135:317-323.
    • (2006) Br J Haematol , vol.135 , pp. 317-323
    • Wu, S.J.1    Yao, M.2    Chou, W.C.3    Tang, J.L.4    Chen, C.Y.5    Ko, B.S.6
  • 27
    • 60849089645 scopus 로고    scopus 로고
    • Aberrant DNA methylation is a dominant mechanism in MDS progression to AML
    • Jiang Y., Dunbar A., Gondek L.P., Mohan S., Rataul M., O'Keefe C., et al. Aberrant DNA methylation is a dominant mechanism in MDS progression to AML. Blood 2009, 113:1315-1325.
    • (2009) Blood , vol.113 , pp. 1315-1325
    • Jiang, Y.1    Dunbar, A.2    Gondek, L.P.3    Mohan, S.4    Rataul, M.5    O'Keefe, C.6
  • 28
    • 0141502199 scopus 로고    scopus 로고
    • Methylation of p15INK4B is common, is associated with deletion of genes on chromosome arm 7q and predicts a poor prognosis in therapy-related myelodysplasia and acute myeloid leukemia
    • Christiansen D.H., Andersen M.K., Pedersen-Bjergaard J. Methylation of p15INK4B is common, is associated with deletion of genes on chromosome arm 7q and predicts a poor prognosis in therapy-related myelodysplasia and acute myeloid leukemia. Leukemia 2003, 17:1813-1819.
    • (2003) Leukemia , vol.17 , pp. 1813-1819
    • Christiansen, D.H.1    Andersen, M.K.2    Pedersen-Bjergaard, J.3
  • 29
    • 37249040925 scopus 로고    scopus 로고
    • Negative effect of DNA hypermethylation on the outcome of intensive chemotherapy in older patients with high-risk myelodysplastic syndromes and acute myeloid leukemia following myelodysplastic syndrome
    • Grövdal M., Khan R., Aggerholm A., Antunovic P., Astermark J., Bernell P., et al. Negative effect of DNA hypermethylation on the outcome of intensive chemotherapy in older patients with high-risk myelodysplastic syndromes and acute myeloid leukemia following myelodysplastic syndrome. Clin Cancer Res 2007, 13:7107-7112.
    • (2007) Clin Cancer Res , vol.13 , pp. 7107-7112
    • Grövdal, M.1    Khan, R.2    Aggerholm, A.3    Antunovic, P.4    Astermark, J.5    Bernell, P.6
  • 30
    • 62849104641 scopus 로고    scopus 로고
    • Efficacy of azacitidine compared with that of conventional care regimens in the treatment of higher-risk myelodysplastic syndromes: a randomised, open-label, phase III study
    • Fenaux P., Mufti G.J., Hellstrom-Lindberg E., Santini V., Finelli C., Giagounidis A., et al. Efficacy of azacitidine compared with that of conventional care regimens in the treatment of higher-risk myelodysplastic syndromes: a randomised, open-label, phase III study. Lancet Oncol 2009, 10:223-232.
    • (2009) Lancet Oncol , vol.10 , pp. 223-232
    • Fenaux, P.1    Mufti, G.J.2    Hellstrom-Lindberg, E.3    Santini, V.4    Finelli, C.5    Giagounidis, A.6
  • 31
    • 62249219780 scopus 로고    scopus 로고
    • Optimal sequencing of treatments for patients with myelodysplastic syndromes
    • Itzykson R., Fenaux P. Optimal sequencing of treatments for patients with myelodysplastic syndromes. Curr Opin Hematol 2009, 16:77-83.
    • (2009) Curr Opin Hematol , vol.16 , pp. 77-83
    • Itzykson, R.1    Fenaux, P.2
  • 32
    • 23744468972 scopus 로고    scopus 로고
    • Expression and methylation status of the FHIT gene in acute myeloid leukemia and myelodysplastic syndrome
    • Iwai M., Kiyoi H., Ozeki K., Kinoshita T., Emi N., Ohno R., et al. Expression and methylation status of the FHIT gene in acute myeloid leukemia and myelodysplastic syndrome. Leukemia 2005, 19:1367-1375.
    • (2005) Leukemia , vol.19 , pp. 1367-1375
    • Iwai, M.1    Kiyoi, H.2    Ozeki, K.3    Kinoshita, T.4    Emi, N.5    Ohno, R.6
  • 33
    • 0037108309 scopus 로고    scopus 로고
    • Demethylation of a hypermethylated P15/INK4B gene in patients with myelodysplastic syndrome by 5-aza-2'-deoxycytidine (decitabine) treatment
    • Daskalakis M., Nguyen T.T., Nguyen C., Guldberg P., Köhler G., Wijermans P., et al. Demethylation of a hypermethylated P15/INK4B gene in patients with myelodysplastic syndrome by 5-aza-2'-deoxycytidine (decitabine) treatment. Blood 2002, 100:2957-2964.
    • (2002) Blood , vol.100 , pp. 2957-2964
    • Daskalakis, M.1    Nguyen, T.T.2    Nguyen, C.3    Guldberg, P.4    Köhler, G.5    Wijermans, P.6
  • 34
    • 33947281469 scopus 로고    scopus 로고
    • Survival advantage with decitabine chemotherapy in patients with myelodysplastic syndrome
    • Kantarjian H.M., O'Brien S., Huang X., Garcia-Manero G., Ravandi F., Cortes J., et al. Survival advantage with decitabine chemotherapy in patients with myelodysplastic syndrome. Cancer 2007, 109:1133-1137.
    • (2007) Cancer , vol.109 , pp. 1133-1137
    • Kantarjian, H.M.1    O'Brien, S.2    Huang, X.3    Garcia-Manero, G.4    Ravandi, F.5    Cortes, J.6
  • 35
    • 34548131144 scopus 로고    scopus 로고
    • CDKN2B methylation status and isolated chromosome 7 abnormalities predict responses to treatment with 5-azacytidine
    • Raj K., John A., Ho A., Chronis C., Khan S., Samuel J., et al. CDKN2B methylation status and isolated chromosome 7 abnormalities predict responses to treatment with 5-azacytidine. Leukemia 2007, 21:1937-1944.
    • (2007) Leukemia , vol.21 , pp. 1937-1944
    • Raj, K.1    John, A.2    Ho, A.3    Chronis, C.4    Khan, S.5    Samuel, J.6


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