Murine metabolism and absorption of lancemaside A, an active compound in the roots of Codonopsis lanceolata

Journal of Natural Medicines

Volumn 64, Issue 3, 2010, Pages 321-329

  Komoto, Noriko ^a   Ichikawa, Makoto ^a   Ohta, Sanae ^a   Nakano, Daisuke ^a   Nishihama, Takeshi ^a   Ushijima, Mitsuyasu ^a   Kodera, Yukihiro ^a   Hayama, Minoru ^a   Shirota, Osamu ^b   Sekita, Setsuko ^b   Kuroyanagi, Masanori ^c  

^a WAKUNAGA PHARMACEUTICAL CO LTD   (Japan)

^b TOKUSHIMA BUNRI UNIVERSITY   (Japan)

^c PREFECTURAL UNIVERSITY OF HIROSHIMA   (Japan)

Author keywords

Bioavailability; Codonolaside II; Codonopsis lanceolata; Echinocystic acid; Lancemaside A; Metabolism

Indexed keywords

28 O ALPHA LEVO RHAMNOPYRANOSYL(1-2) ALPHA LEVO ARABINOPYRANOSYL ESTER; 28 O BETA DEXTRO XYLOPYRANOSYL(1-4) ALPHA LEVO RHAMNOPYRANOSYL(1-2) ALPHA LEVO ARABINOPYRANOSYL ESTER; CODONOLASIDE II; DRUG METABOLITE; ECHINOCYSTIC ACID; LANCEMASIDE A; SAPONIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; CECUM; CODONOPSIS; CODONOPSIS LANCEOLATA; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG ELIMINATION; DRUG HALF LIFE; GASTROINTESTINAL ABSORPTION; INTESTINE FLORA; MALE; MAXIMUM PLASMA CONCENTRATION; MOUSE; NONHUMAN; PLANT ROOT; SINGLE DRUG DOSE; TIME TO MAXIMUM PLASMA CONCENTRATION;

ADMINISTRATION, ORAL; ANIMALS; CECUM; CHROMATOGRAPHY, LIQUID; CODONOPSIS; ESTERS; MALE; MASS SPECTROMETRY; MICE; MOLECULAR STRUCTURE; OLEANOLIC ACID; PLANT ROOTS; SAPONINS;

EID: 77953610857     PISSN: 13403443     EISSN: 18610293     Source Type: Journal    
DOI: 10.1007/s11418-010-0415-8     Document Type: Article

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