Peripheral μ-, K{green}- and δ-opioid receptors mediate the hypoalgesic effect of celecoxib in a rat model of thermal hyperalgesia

Life Sciences

Volumn 86, Issue 25-26, 2010, Pages 951-956

  Correa, Jôice D ^a   Paiva Lima, Patrícia ^a   Rezende, Rafael M ^a   Dos Reis, Webster G P ^a   Ferreira Alves, Dalton L ^a   Bakhle, Y S ^b   Francischi, Janetti N ^a  

^a FEDERAL UNIVERSITY OF MINAS GERAIS   (Brazil)

^b NATIONAL HEART AND LUNG INSTITUTE   (United Kingdom)

Author keywords

Celecoxib; Cyclooxygenase inhibition; Hargreave's method; Hypoalgesia; Opioid receptors

Indexed keywords

4 [5 (4 CHLOROPHENYL) 3 TRIFLUOROMETHYL 1H PYRAZOL 1 YL]BENZENESULFONAMIDE; BETA FUNALTREXAMINE; CELECOXIB; DELTA OPIATE RECEPTOR; INDOMETACIN; KAPPA OPIATE RECEPTOR; MU OPIATE RECEPTOR; NALTREXONE; NALTRINDOLE; NORBINALTORPHIMINE; CARRAGEENAN; CYCLOOXYGENASE 2 INHIBITOR; OPIATE RECEPTOR; PYRAZOLE DERIVATIVE; SULFONAMIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG RECEPTOR BINDING; HYPERALGESIA; HYPOALGESIA; MECHANICAL STIMULATION; NOCICEPTION; NONHUMAN; PAIN THRESHOLD; RAT; STIMULUS RESPONSE; THERMAL STIMULATION; ANIMAL; DISEASE MODEL; DRUG ANTAGONISM; DRUG EFFECT; MALE; METABOLISM; PATHOPHYSIOLOGY; STIMULATION; TEMPERATURE;

RATTUS;

ANIMALS; CARRAGEENAN; CYCLOOXYGENASE 2 INHIBITORS; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; HYPERALGESIA; MALE; PAIN THRESHOLD; PHYSICAL STIMULATION; PYRAZOLES; RATS; RECEPTORS, OPIOID; RECEPTORS, OPIOID, DELTA; RECEPTORS, OPIOID, KAPPA; RECEPTORS, OPIOID, MU; SULFONAMIDES; TEMPERATURE;

EID: 77953610244     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.lfs.2010.04.012     Document Type: Article

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