DHEA therapy in postmenopausal women: the need to move forward beyond the lack of evidence

Climacteric

Volumn 13, Issue 4, 2010, Pages 314-316

  Genazzani, A R ^a   Pluchino, N ^a  

^a UNIVERSITY OF PISA   (Italy)

Author keywords

Dehydroepiandrosterone; Dehydroepiandrosterone sulfate. hormone therapy; Postmenopause

Indexed keywords

PRASTERONE; PRASTERONE SULFATE;

AGING; ANDROGEN BLOOD LEVEL; ANDROGEN DEFICIENCY; FEMALE; HORMONE SUBSTITUTION; HUMAN; POSTMENOPAUSE; PRESCRIPTION; PRIORITY JOURNAL; SHORT SURVEY; BLOOD; DEFICIENCY; PHYSIOLOGY; PROCEDURES; SEXUAL BEHAVIOR;

AGING; DEHYDROEPIANDROSTERONE; DEHYDROEPIANDROSTERONE SULFATE; FEMALE; HORMONE REPLACEMENT THERAPY; HUMANS; POSTMENOPAUSE; SEXUAL BEHAVIOR;

EID: 77953569334     PISSN: 13697137     EISSN: 14730804     Source Type: Journal    
DOI: 10.3109/13697137.2010.492496     Document Type: Short Survey

References (9)

1. Panjari M, Davis SR. DHEA for postmenopausal women: A review of the evidence? Maturitas 2010;Jan 18. Epub ahead of print
2. Labrie F, Luu-The V, Bélanger A, et al. Is dehydroepiandrosterone a hormone? J Endocrinol 2005;187: 169-196
3. Davis SR, Davison SL, Donath S, et al. Circulating androgen levels and self-reported sexual function in women. JAMA 2005;294:91-96 (Pubitemid 41002843)
4. Davis SR, Shah SM, McKenzie DP, et al. Dehydroepiandrosterone sulfate levels are associated with more favorable cognitive function in women. J Clin Endocrinol Metab 2008;93:801-808
5. Genazzani AR, Pluchino N, Begliuomini S, et al. Long-term low-dose oral administration of dehydroepiandrosterone modulates adrenal response to adrenocorticotropic hormone in early and late postmenopausal women. Gynecol Endocrinol 2006;22: 627-635
6. Maninger N, Wolkowitz OM, Reus VI, et al. Neurobiological and neuropsychiatric effects of dehydroepiandrosterone (DHEA) and DHEA sulfate (DHEAS). Front Neuroendocrinol 2009;30:65-91
7. Simoncini T, Mannella P, Fornari L, et al. Dehydroepiandrosterone modulates endothelial nitric oxide synthesis via direct genomic and nongenomic mechanisms. Endocrinology 2003;144:3449-3455
8. Labrie F, Archer D, Bouchard C, et al. Serum steroid levels during 12-week intravaginal dehydroepiandrosterone administration. Menopause 2009;16:897-906
9. Pluchino N, Ninni F, Stomati M, et al. One-year therapy with 10 mg/day DHEA alone or in combination with HRT in postmenopausal women: effects on hormonal milieu. Maturitas 2008;59:293-303