Nanoparticle-Enhanced MRI to Evaluate Radiation Delivery to the Regional Lymphatics for Patients With Breast Cancer

International Journal of Radiation Oncology Biology Physics

Volumn 77, Issue 4, 2010, Pages 1098-1104

  MacDonald, Shannon M ^a   Harisinghani, Mukesh G ^a   Katkar, Amol ^a   Napolitano, Brian ^a   Wolfgang, John ^a   Taghian, Alphonse G ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

Breast cancer; lymphatic delineation; nanoparticle; nodal mapping; radiation planning

Indexed keywords

BREAST CANCER; LYMPH NODE; LYMPHATIC DELINEATION; RADIATION DELIVERY; RADIATION PLANNING;

BODY FLUIDS; NANOPARTICLES; PHYSICAL THERAPY;

RADIOTHERAPY;

NANOPARTICLE; ULTRASMALL SUPERPARAMAGNETIC IRON OXIDE;

ADULT; AGED; ARTICLE; BREAST CANCER; CANCER PATIENT; CANCER RADIOTHERAPY; CLINICAL ARTICLE; COMPUTER ASSISTED TOMOGRAPHY; DOSIMETRY; HUMAN; LYMPHATIC SYSTEM; NUCLEAR MAGNETIC RESONANCE IMAGING; PRESCRIPTION; PRIORITY JOURNAL; RADIATION DOSE; RADIATION DOSE DISTRIBUTION;

ADULT; AGED; AGED, 80 AND OVER; BREAST NEOPLASMS; CONTRAST MEDIA; DEXTRANS; FEMALE; FERROSOFERRIC OXIDE; HUMANS; LYMPH NODES; LYMPHATIC IRRADIATION; LYMPHATIC METASTASIS; MAGNETIC RESONANCE IMAGING; MIDDLE AGED; NANOPARTICLES; RADIOTHERAPY DOSAGE; RADIOTHERAPY PLANNING, COMPUTER-ASSISTED;

EID: 77953561686     PISSN: 03603016     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijrobp.2009.06.002     Document Type: Article

References (29)

1. Overgaard M., Jensen M.B., Overgaard J., et al. Postoperative radiotherapy in high-risk postmenopausal breast-cancer patients given adjuvant tamoxifen: Danish Breast Cancer Cooperative Group DBCG 82c randomised trial. Lancet 353 (1999) 1641-1648
2. Ragaz J., Olivotto I.A., Spinelli J.J., et al. Locoregional radiation therapy in patients with high-risk breast cancer receiving adjuvant chemotherapy: 20-year results of the British Columbia randomized trial. J Natl Cancer Inst 97 (2005) 116-126
3. Recht A., Edge S.B., Solin L.J., et al. Postmastectomy radiotherapy: Clinical practice guidelines of the American Society of Clinical Oncology. J Clin Oncol 19 (2001) 1539-1569
4. Overgaard M., Hansen P.S., Overgaard J., et al. Postoperative radiotherapy in high-risk premenopausal women with breast cancer who receive adjuvant chemotherapy. Danish Breast Cancer Cooperative Group 82b Trial. N Engl J Med 337 (1997) 949-955
5. Formenti S.C., Gidea-Addeo D., Goldberg J.D., et al. Phase I-II trial of prone accelerated intensity modulated radiation therapy to the breast to optimally spare normal tissue. J Clin Oncol 25 (2007) 2236-2242
6. Freedman G.M., Anderson P.R., Goldstein L.J., et al. Four-week course of radiation for breast cancer using hypofractionated intensity modulated radiation therapy with an incorporated boost. Int J Radiat Oncol Biol Phys 68 (2007) 347-353
7. Croog V.J., Wu A.J., McCormick B., et al. Accelerated whole breast irradiation with intensity-modulated radiotherapy to the prone breast. Int J Radiat Oncol Biol Phys 73 (2009) 88-93
8. Krueger E.A., Fraass B.A., McShan D.L., et al. Potential gains for irradiation of chest wall and regional nodes with intensity modulated radiotherapy. Int J Radiat Oncol Biol Phys 56 (2003) 1023-1037
9. Krueger E.A., Fraass B.A., and Pierce L.J. Clinical aspects of intensity-modulated radiotherapy in the treatment of breast cancer. Semin Radiat Oncol 12 (2002) 250-259
10. White J, Tai A, Arthur D, et al. Breast cancer atlas for radiation planning; consensus definitions; Radiation Therapy Oncology Group (RTOG). Available at: http://www.rtog.org/pdf_file2.html?pdf_document=BreastCancerAtlas.pdf.
11. Li X.A., Tai A., Arthur D.W., et al. Variability of target and normal structure delineation for breast cancer radiotherapy: An RTOG Multi-Institutional and Multiobserver Study. Int J Radiat Oncol Biol Phys 73 (2009) 944-951
12. Harada T., Tanigawa N., Matsuki M., et al. Evaluation of lymph node metastases of breast cancer using ultrasmall superparamagnetic iron oxide-enhanced magnetic resonance imaging. Eur J Radiol 63 (2007) 401-407
13. Memarsadeghi M., Riedl C.C., Kaneider A., et al. Axillary lymph node metastases in patients with breast carcinomas: Assessment with nonenhanced versus uspio-enhanced MR imaging. Radiology 241 (2006) 367-377
14. Weissleder R., Heautot J.F., Schaffer B.K., et al. MR lymphography: Study of a high-efficiency lymphotrophic agent. Radiology 191 (1994) 225-230
15. Saksena M., Harisinghani M., Hahn P., et al. Comparison of lymphotropic nanoparticle-enhanced MRI sequences in patients with various primary cancers. AJR Am J Roentgenol 187 (2006) W582-W588
16. Saokar A., Braschi M., and Harisinghani M.G. Lymphotrophic nanoparticle enhanced MR imaging (LNMRI) for lymph node imaging. Abdom Imaging (2009) In press
17. Kroon B.K., and Horenblas S. Re: Regional lymph node staging using lymphotropic nanoparticle enhanced magnetic resonance imaging with ferumoxtran-10 in patients with penile cancer. J Urol 175 (2006) 1174
18. Saksena M.A., Saokar A., and Harisinghani M.G. Lymphotropic nanoparticle enhanced MR imaging (LNMRI) technique for lymph node imaging. Eur J Radiol 58 (2006) 367-374
19. Will O., Purkayastha S., Chan C., et al. Diagnostic precision of nanoparticle-enhanced MRI for lymph-node metastases: a meta-analysis. Lancet Oncol 7 (2006) 52-60
20. Shih H.A., Harisinghani M., Zietman A.L., et al. Mapping of nodal disease in locally advanced prostate cancer: Rethinking the clinical target volume for pelvic nodal irradiation based on vascular rather than bony anatomy. Int J Radiat Oncol Biol Phys 63 (2005) 1262-1269
21. Hack T.F., Cohen L., Katz J., et al. Physical and psychological morbidity after axillary lymph node dissection for breast cancer. J Clin Oncol 17 (1999) 143-149
22. Ververs J.M., Roumen R.M., Vingerhoets A.J., et al. Risk, severity and predictors of physical and psychological morbidity after axillary lymph node dissection for breast cancer. Eur J Cancer 37 (2001) 991-999
23. Veronesi U., Paganelli G., Viale G., et al. A randomized comparison of sentinel-node biopsy with routine axillary dissection in breast cancer. N Engl J Med 349 (2003) 546-553
24. McLaughlin S.A., Wright M.J., Morris K.T., et al. Prevalence of lymphedema in women with breast cancer 5 years after sentinel lymph node biopsy or axillary dissection: Objective measurements. J Clin Oncol 26 (2008) 5213-5219
25. Gadd M.H.J., Taghian A., et al. Prospective study of axillary radiation without axillary dissection for breast cancer patients with a positive sentinel node. Breast Cancer Res Treat 94 (2005) S12
26. Hurkmans C.W., Borger J.H., Rutgers E.J., et al. Quality assurance of axillary radiotherapy in the EORTC AMAROS trial 10981/22023: The dummy run. Radiother Oncol 68 (2003) 233-240
27. Mansel R.E., and Goyal A. European studies on breast lymphatic mapping. Semin Oncol 31 (2004) 304-310
28. Rutgers E.J., Meijnen P., and Bonnefoi H. Clinical trials update of the European Organization for Research and Treatment of Cancer Breast Cancer Group. Breast Cancer Res 6 (2004) 165-169
29. Reed V.K., Cavalcanti J.L., Strom E.A., et al. Risk of subclinical micrometastatic disease in the supraclavicular nodal bed according to the anatomic distribution in patients with advanced breast cancer. Int J Radiat Oncol Biol Phys 71 (2008) 435-440