Four-Week Course of Radiation for Breast Cancer Using Hypofractionated Intensity Modulated Radiation Therapy With an Incorporated Boost

International Journal of Radiation Oncology Biology Physics

Volumn 68, Issue 2, 2007, Pages 347-353

  Freedman, Gary M ^a   Anderson, Penny R ^a   Goldstein, Lori J ^a   Ma, Chang Ming ^a   Li, Jinsheng ^a   Swaby, Ramona F ^a   Litwin, Samuel ^a   Watkins Bruner, Deborah ^b   Sigurdson, Elin R ^a   Morrow, Monica ^a  

^a FOX CHASE CANCER CENTER   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Breast boost; Breast cancer; Hypofractionation; Intensity modulated radiation therapy; Radiation therapy

Indexed keywords

ELECTRON BEAMS; HOSPITALS; RADIATION; RADIOTHERAPY; SKIN; SURGERY; TOXICITY; TUMORS;

BREAST BOOST; BREAST CANCER; HYPOFRACTIONATION; INTENSITY MODULATED RADIATION THERAPY;

ONCOLOGY;

ACUTE TOXICITY; ADULT; AGED; ANEMIA; ARTICLE; BLOOD TOXICITY; BREAST CANCER; CANCER CHEMOTHERAPY; CANCER INVASION; CANCER RADIOTHERAPY; CANCER STAGING; CARCINOMA IN SITU; CONTROLLED STUDY; ELECTRON BEAM; ELECTRON THERAPY; FEMALE; FOLLOW UP; HOSPITAL; HUMAN; MAJOR CLINICAL STUDY; NEUTROPENIA; PARTIAL MASTECTOMY; PHOTON THERAPY; PRIORITY JOURNAL; QUALITY OF LIFE; RADIATION DOSE; SKIN TOXICITY; TREATMENT DURATION;

ADULT; AGED; AGED, 80 AND OVER; BREAST NEOPLASMS; CARCINOMA, INTRADUCTAL, NONINFILTRATING; DOSE FRACTIONATION; FEMALE; HUMANS; MIDDLE AGED; NEOPLASM STAGING; RADIOTHERAPY, INTENSITY-MODULATED; RELATIVE BIOLOGICAL EFFECTIVENESS;

EID: 34247877882     PISSN: 03603016     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijrobp.2006.12.035     Document Type: Article

References (40)

1. National Comprehensive Cancer Network. NCCN clinical practice guidelines in oncology. Breast cancer version 1.2007. Available at: http://www.nccn.org/professionals/physician_gls/PDF/breast.pdf. Accessed February 8, 2007.
2. NIH Consensus Conference. Treatment of early-stage breast cancer. JAMA 265 (1991) 391-395
3. Early Breast Cancer Trialists' Collaborative Group. Effects of radiotherapy and of differences in the extent of surgery for early breast cancer on local recurrence and 15-year survival: An overview of the randomised trials. Lancet 366 (2005) 2087-2106
4. Lazovich D., Solomon C.C., Thomas D.B., et al. Breast conservation therapy in the United States following the 1990 National Institutes of Health Consensus Development Conference on the treatment of patients with early stage invasive breast carcinoma. Cancer 86 (1999) 628-637
5. Morrow M., White J., Moughan J., et al. Factors predicting the use of breast-conserving therapy in stage I and II breast carcinoma. J Clin Oncol 19 (2001) 2254-2262
6. Polednak A.P. Trends in, and predictors of, breast-conserving surgery and radiotherapy for breast cancer in Connecticut, 1988-1997. Int J Radiat Oncol Biol Phys 53 (2002) 157-163
7. American Joint Committee on Cancer. AJCC cancer staging manual. 5th ed. (1997), Lippincott-Raven, Philadelphia
8. Li J., Freedman G., Price R., et al. Clinical implementation of intensity-modulated tangential beam irradiation for breast cancer. Med Phys 31 (2004) 1023-1031
9. Cancer Therapy Evaluation Program. Common Terminology Criteria for Adverse Events: National Cancer Institute. Available at: http://ctep.cancer.gov/forms/CTCAEv3.pdf.
10. Aaronson N.K., Bartelink H., van Dongen J., et al. Evaluation of breast conserving therapy: Clinical, methodological and psychosocial perspectives. Eur J Surg Oncol 14 (1988) 133-140
11. Stanton A.L., Krishnan L., and Collins C.A. Form or function? Part 1. Subjective cosmetic and functional correlates of quality of life in women treated with breast-conserving surgical procedures and radiotherapy. Cancer 91 (2001) 2273-2281
12. Krishnan L., Stanton A.L., Collins C.A., et al. Form or function? Part 2. Objective cosmetic and functional correlates of quality of life in women treated with breast-conserving surgical procedures and radiotherapy. Cancer 91 (2001) 2282-2287
13. Fowler J.F. The linear-quadratic formula and progress in fractionated radiotherapy. Br J Radiol 62 (1989) 679-694
14. Olivotto I.A., Weir L.M., Kim-Sing C., et al. Late cosmetic results of short fractionation for breast conservation. Radiother Oncol 41 (1996) 7-13
15. Shelley W., Brundage M., Hayter C., et al. A shorter fractionation schedule for postlumpectomy breast cancer patients. Int J Radiat Oncology Biol Phys 47 (2000) 1219-1228
16. Dewar J.A., Arriagada R., Benhamou S., et al. Local relapse and contralateral tumor rates in patients with breast cancer treated with conservative surgery and radiotherapy (Institut Gustave Roussy 1970-1982). Cancer 76 (1995) 2260-2265
17. Clark R.M., Wilkinson R.H., Miceli P.N., et al. Breast cancer: Experiences with conservative therapy. Am J Clin Oncol 10 (1987) 461-468
18. Whelen T., MacKenzie R., Julian J., et al. Randomized trial of breast irradiation schedules after lumpectomy for women with lymph node-negative breast cancer. J Natl Cancer Inst 94 (2002) 1143-1150
19. Bartelink H., Horiot J., Poortmans P., et al. Recurrence rates after treatment of breast cancer with standard radiotherapy with or without additional radiation. N Engl J Med 345 (2001) 1378-1387
20. Romestaing P., Lehingue Y., Carrie C., et al. Role of a 10-Gy boost in the conservative treatment of early breast cancer: Results of a randomized clinical trial in Lyon, France. J Clin Oncol 15 (1997) 963-968
21. Xiong W., Li J., Chen L., et al. Optimization of combined electron and photon beams for breast cancer. Phys Med Biol 49 (2004) 1973-1989
22. Buchholz T.A., Gurgoze E., Bice W.S., et al. Dosimetric analysis of intact breast irradiation in off-axis planes. Int J Radiat Oncol Biol Phys 39 (1997) 109-115
23. Das I.J., Cheng C., Fein D.A., et al. Patterns of dose variability in radiation prescription of breast cancer. Radiother Oncol 44 (1997) 83-89
24. Chin L.M., Cheng C.W., Siddon R.L., et al. Three-dimensional photon dose distributions with and without lung corrections for tangential breast intact treatments. Int J Radiat Oncol Biol Phys 17 (1989) 1327-1335
25. Solin L.J., Chu J.C.H., Sontag M.R., et al. Three-dimensional photon treatment planning of the intact breast. Int J Radiat Oncol Biol Phys 21 (1991) 193-203
26. Back M., Guerrieri M., Wratten C., et al. Impact of radiation therapy on acute toxicity in breast conservation therapy for early breast cancer. Clin Oncol 16 (2004) 12-16
27. Fisher J., Scott C., Stevens R., et al. Randomized phase III study comparing best supportive care to Biafine as a prophylactic agent for radiation-induced skin toxicity for women undergoing breast irradiation: Radiation Therapy Oncology Group (RTOG) 97-13. Int J Radiat Oncol Biol Phys 48 (2000) 1307-1310
28. Neal A.J., Torr M., Helyer S., et al. Correlation of breast dose heterogeneity with breast size using 3D CT planning and dose-volume histograms. Radiother Oncol 34 (1995) 210-218
29. Taylor M.E., Perez C.A., Halverson K.J., et al. Factors influencing cosmetic results after conservation therapy for breast cancer. Int J Radiat Oncol Biol Phys 31 (1995) 753-764
30. Gorodetsky R., Lotan C., Piggot K., et al. Late effects of dose fractionation on the mechanical properties of breast skin following post-lumpectomy radiotherapy. Int J Radiat Oncol Biol Phys 45 (1999) 893-900
31. Johansson S., Svensson H., and Denekamp J. Dose response and latency for radiation-induced fibrosis, edema, and neuropathy in breast cancer patients. Int J Radiat Oncol Biol Phys 52 (2002) 1207-1219
32. Intensity Modulated Radiation Therapy Collaborative Working Group. Intensity-modulated radiotherapy: Current status and issues of interest. Int J Radiat Oncol Biol Phys 51 (2001) 880-914
33. Hong L., Hunt M., Chui C., et al. Intensity-modulated tangential beam irradiation of the intact breast. Int J Radiat Oncol Biol Phys 44 (1999) 1155-1164
34. Kestin L.L., Sharpe M.B., Frazier R.C., et al. Intensity modulation to improve dose uniformity with tangential breast radiotherapy: Initial clinical experience. Int J Radiat Oncol Biol Phys 48 (2000) 1559-1568
35. Hurkmans C.W., Cho B.C.J., Damen E., et al. Reduction of cardiac and lung complication probabilities after breast irradiation using conformal radiotherapy with or without intensity modulation. Radiother Oncol 62 (2002) 163-171
36. Vicini F.A., Sharpe M., Kestin L., et al. Optimizing breast cancer treatment efficacy with intensity-modulated radiotherapy. Int J Radiat Oncol Biol Phys 54 (2002) 1336-1344
37. Yarnold J., Donovan E., Bleackley N., et al. Randomized trial of standard 2D radiotherapy (RT) versus 3D intensity modulated radiotherapy (IMRT) in patients prescribed breast radiotherapy. Radiother Oncol 64 (2002) S15
38. Freedman G.M., Anderson P.R., Li J., et al. Intensity modulated radiation therapy (IMRT) decreases the acute skin toxicity for women receiving radiation therapy for breast cancer. Am J Clin Oncol 29 (2006) 66-70
39. Frassica D.A., Bajaj G.K., and Tsangaris T.N. Treatment of complications after breast-conservation therapy. Oncology 17 (2003) 1118-1128
40. Indelicato D.J., Grobmyer S.R., Newlin H., et al. Delayed breast cellulitis: An evolving complication of breast conservation. Int J Radiat Oncol Biol Phys 66 (2006) 1339-1346