Analgesic and anti-inflammatory activities of the aqueous extracts from three flemingia species

American Journal of Chinese Medicine

Volumn 38, Issue 3, 2010, Pages 625-638

  Ko, Yu Jen ^a   Lu, Tsung Chun ^b   Kitanaka, Susumu ^d   Liu, Chia Yu ^b,e   Wu, Jin Bin ^c   Kuo, Chao Lin ^a   Cheng, Hao Yuan ^g   Lin, Ying Chih ^f   Peng, Wen Huang ^b  

^a School of Chinese Medicine Resources   (China)

^b Graduate Institute of Chinese Pharmaceutical Sciences   (China)

^c CHINA MEDICAL UNIVERSITY   (Taiwan)

^d NIHON UNIVERSITY   (Japan)

^e Department of Nursing ^*  (China)

^f JEN TEH JUNIOR COLLEGE OF MEDICINE   (Taiwan)

^g Health Science and Management   (Taiwan)

Author keywords

Analgesia; Anti inflammation; Flemingia; MDA; NO; SOD

Indexed keywords

ACETIC ACID; CARRAGEENAN; FLEMINGIA LINEATA EXTRACT; FLEMINGIA MACROPHYLLA EXTRACT; FLEMINGIA PROSTRATA EXTRACT; FORMALDEHYDE; GLUTATHIONE PEROXIDASE; GLUTATHIONE REDUCTASE; INDOMETACIN; MALONALDEHYDE; NITRIC OXIDE; PLANT EXTRACT; SUPEROXIDE DISMUTASE; UNCLASSIFIED DRUG;

ANALGESIC ACTIVITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG MECHANISM; FLEMINGIA LINEATA; FLEMINGIA MACROPHYLLA; FLEMINGIA PROSTRATA; MALE; MEDICINAL PLANT; MOUSE; NONHUMAN; PAW EDEMA; PLANT ROOT; WRITHING TEST;

ANALGESICS; ANIMALS; ANTI-INFLAMMATORY AGENTS; CARRAGEENAN; DOSE-RESPONSE RELATIONSHIP, DRUG; EDEMA; FABACEAE; GLUTATHIONE PEROXIDASE; GLUTATHIONE REDUCTASE; HINDLIMB; LIVER; MALE; MALONDIALDEHYDE; MICE; MICE, INBRED ICR; NITRIC OXIDE; PAIN MEASUREMENT; PHYTOTHERAPY; PLANT EXTRACTS; PLANT ROOTS; SPECIES SPECIFICITY; SUPEROXIDE DISMUTASE; TREATMENT OUTCOME; WATER;

EID: 77953549631     PISSN: 0192415X     EISSN: None     Source Type: Journal    
DOI: 10.1142/S0192415X1000810X     Document Type: Article

References (30)

1. Brubaker, C.L. and N.R. Lersten. Paraveinal mesophyll: review and survey of the subtribe Erythrininae (Phaseoleae, Papilionoideae, Leguminosae). Plant. Syst. Evol. 196: 31-62, 1995.
2. Carlberg, I. and B. Mannervik. Glutathione reductase. Methods Enzymol. 113: 484-490, 1985.
3. Cuzzocrea, S., B. Zingarelli, E. Gilad, P. Hake, A.L. Salzman and C. Szabo. Protective effect of melatonin in carrageenan-induced models of local inflammation: relationship to its inhibitory effect on nitric oxide production and its peroxynitrite scavenging activity. J. Pineal Res. 23: 106-116, 1997.
4. Cuzzocrea, S., G. Costantino, B. Zingarelli, E. Mazzon, A. Micali and A.P. Caputi. The protective role of endogenous glutathione in carrageenan-induced pleurisy in the rat. Eur. J. Pharmacol. 372: 187-197, 1999. (Pubitemid 29251291)
5. 2+ homeostasis in Raillietina echinobothrida, the cestode of domestic fowl. Parasitol. Int. 55: 17-21, 2006.
6. Dawson, J., A.D. Sedgwick, J.C. Edwards and P. Lees. A comparative study of the cellular, exudative and histological responses to carrageenan, dextran and zymosan in the mouse. Int. J. Tissue React. 13: 171-185, 1991.
7. Di Rosa, M., J.P. Giroud and D.A. Willoughby. Studies on the mediators of the acute inflammatory response induced in rats in different sites by carrageenan and turpentine. J. Pathol. 104: 15-29, 1971.
8. DiSilvestro, R.A. and J.T. Marten. Effects of inflammation and copper intake on rat liver and erythrocyte Cu-Zn superoxide dismutase activity levels. J. Nutr. 120: 1223-1227, 1990.
9. Dubuisson, D. and S.G. Dennis. The formalin test: a quantitative study of the analgesic effects of morphine, meperidine, and brain stem stimulation in rats and cats. Pain 4: 161-174, 1977.
10. Dudhgaonkar, S.P., S.K. Tandan, A.S. Bhat, S.H. Jadhav and D. Kumar. Synergistic anti-inflammatory interaction between meloxicam and aminoguanidine hydrochloride in carrageenaninduced acute inflammation in rats. Life Sci. 78: 1044-1048, 2006.
11. Flohe, L. and W.A. Gunzler. Assays of glutathione peroxidase. Methods Enzymol. 105: 114-121, 1984.
12. Ho, Y.L., K.C. Kao, H.Y. Tsai, F.Y. Chueh and Y.S. Chang. Evaluation of antinociceptive, antiinflammatory and antipyretic effects of Strobilanthes cusia leaf extract in male mice and rats. Am. J. Chin. Med. 31: 61-69, 2003.
13. Hunskaar, S., O.B. Fasmer and K. Hole. Formalin test in mice, a useful technique for evaluating mild analgesics. J. Neurosci. Methods 14: 69-76, 1985.
14. Hunskaar, S. and K. Hole. The formalin test in mice: dissociation between inflammatory and noninflammatory pain. Pain 30: 103-114, 1987.
15. Janero, D.R. Malondialdehyde and thiobarbituric acid-reactivity as diagnostic indices of lipid peroxidation and peroxidative tissue injury. Free Radic. Biol. Med. 9: 515-540, 1990.
16. Khaksa, G., M.E. Zolfaghari, A.R. Dehpour and T. Samadian. Anti-inflammatory and anti-nociceptive activity of disodium glycyrrhetinic acid hemiphthalate. Planta Med. 62: 326-328, 1996.
17. Kirkova, M., T. Kassabova and E. Russanov. In vivo effects of indomethacin-I. Activity of antioxidant enzymes and lipid peroxidation. Gen. Pharmacol. 23: 503-507, 1992.
18. Ko, Y.J., Y.W. Wu and W.C. Lin. Hypolipidemic effect of Glycine tomentella root extract in hamsters. Am. J. Chin. Med. 32: 57-63, 2004.
19. Koo, H.J., K.H. Lim, H.J. Jung and E.H. Park. Anti-inflammatory evaluation of gardenia extract, geniposide and genipin. J. Ethnopharmacol. 103: 496-500, 2006.
20. Lai, S.C., W.H. Peng, S.C. Huang, Y.L. Ho, T.H. Huang, Z.R. Lai and Y.S. Chang. Analgesic and anti-inflammatory activities of methanol extract from Desmodium triflorum DC in mice. Am. J. Chin. Med. 37: 573-588, 2009.
21. Lin, C.C., J.M. Lu, J.J. Yang, S.C. Chuang and T. Ujiie. Anti-inflammatory and radical scavenge effects of Arctium lappa. Am. J. Chin. Med. 24: 127-137, 1996.
22. Lin, C.C., Y.F. Hsu and T.C. Lin. Effects of punicalagin and punicalin on carrageenan-induced inflammation in rats. Am. J. Chin. Med. 27: 371-376, 1999.
23. Lu, T.C., Y.Z. Ko, H.W. Huang, Y.C. Hung, Y.C. Lin and W.H. Peng. Analgesic and anti-inflammatory activities of aqueous extract from Glycine tomentella root in mice. J. Ethnopharmacol. 113: 142-148, 2007.
24. Misra, H.P. and I. Fridovich. The role of superoxide anion in the autoxidation of epinephrine and a simple assay for superoxide dismutase. J. Biol. Chem. 247: 3170-3175, 1972.
25. Nims, R.W., J.F. Darbyshire, J.E. Saavedra, D. Christodoulou, I. Hanbauer, G.W. Cox, M.B. Grisham, F. Laval, J.A. Cook, M.C. Krishna and D.A. Wink. Colorimetric methods for the determination of nitric oxide concentration in neutral aqueous solutions Methods 7: 48-54, 1995.
26. Salvemini, D., Z.Q. Wang, D.M. Bourdon, M.K. Stern, M.G. Currie and P.T. Manning. Evidence of peroxynitrite involvement in the carrageenan-induced rat paw edema. Eur. J. Pharmacol. 303: 217-220, 1996.
27. Tatum, V.L., C. Changchit and C.K. Chow. Measurement of malondialdehyde by high performance liquid chromatography with fluorescence detection. Lipids 25: 226-229, 1990.
28. Verdrengh, M., I.M. Jonsson, R. Holmdahl and A. Tarkowski. Genistein as an anti-inflammatory agent. Inflamm. Res. 52: 341-346, 2003.
29. Winter, C.A., E.A. Risley and G.W. Nuss. Carrageenin-induced edema in hind paw of the rat as an assay for antiiflammatory drugs. Proc. Soc. Exp. Biol. Med. 111: 544-547, 1962.
30. Zimmermann, M. Ethical guidelines for investigations of experimental pain in conscious animals. Pain 16: 109-110, 1983.