Poor clinical outcome despite successful arterial recanalization. What went wrong? How can we do better?

Neuroradiology

Volumn 52, Issue 5, 2010, Pages 341-343

  Goyal, Mayank ^a  

^a UNIVERSITY OF CALGARY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

FIBRINOLYTIC AGENT; TISSUE PLASMINOGEN ACTIVATOR;

ACUTE DISEASE; BLOOD CLOT LYSIS; BRAIN ISCHEMIA; CEREBRAL REVASCULARIZATION; CLINICAL TRIAL; EFFECT SIZE; HUMAN; INTERNAL CAROTID ARTERY; INTERVENTION STUDY; MORTALITY; OUTCOME ASSESSMENT; PRIORITY JOURNAL; RECANALIZATION; SHORT SURVEY; STROKE; SYMPTOMATOLOGY;

ACUTE DISEASE; BIOMEDICAL RESEARCH; BRAIN; BRAIN ISCHEMIA; CEREBRAL ARTERIES; CEREBRAL VEINS; CEREBROVASCULAR CIRCULATION; HUMANS; NEUROSURGICAL PROCEDURES; STROKE; THROMBOLYTIC THERAPY; TREATMENT OUTCOME;

EID: 77953543776     PISSN: 00283940     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00234-009-0636-2     Document Type: Short Survey

References (15)

1. Rha JH, Saver JL (2007) The impact of recanalization on ischemic stroke outcome: a meta-analysis. Stroke 38:967-973
2. Heiss WD (2000) Ischemic penumbra: evidence from functional imaging in man. J Cereb Blood Flow Metab 20:1276-1293
3. (1995) Tissue plasminogen activator for acute ischemic stroke. The National Institute of Neurological Disorders and Stroke rt-PA Stroke Study Group. N Engl J Med 333:1581-1587
4. Furlan A, Higashida R, Wechsler L et al (1999) Intra-arterial prourokinase for acute ischemic stroke. The PROACT II study: a randomized controlled trial. Prolyse in Acute Cerebral Thromboembolism. JAMA 282:2003-2011
5. Saqqur M, Uchino K, Demchuk AM et al (2007) Site of arterial occlusion identified by transcranial Doppler predicts the response to intravenous thrombolysis for stroke. Stroke 38:948-954
6. del Zoppo GJ, Poeck K, Pessin MS et al (1992) Recombinant tissue plasminogen activator in acute thrombotic and embolic stroke. Ann Neurol 32:78-86
7. (2004) Combined intravenous and intra-arterial recanalization for acute ischemic stroke: the Interventional Management of Stroke Study. Stroke 35:904-911
8. (2007) The Interventional Management of Stroke (IMS) II Study. Stroke 38:2127-2135
9. Khatri P, Hill MD, Palesch YY et al (2008) Methodology of the interventional management of stroke III trial. Int J Stroke 3:130-137 (Pubitemid 351566847)
10. Gobin YP, Starkman S, Duckwiler GR et al (2004) MERCI 1: a phase 1 study of Mechanical Embolus Removal in Cerebral Ischemia. Stroke 35:2848-2854
11. Smith WS, Sung G, Saver J et al (2008) Mechanical thrombectomy for acute ischemic stroke: final results of the Multi MERCI trial. Stroke 39:1205-1212
12. (2009) The penumbra pivotal stroke trial: safety and effectiveness of a new generation of mechanical devices for clot removal in intracranial large vessel occlusive disease. Stroke 40:2761-2768
13. Uflacker R, Schonholz C, Papamitisakis N (2008) Interim report of the SENTIS trial: cerebral perfusion augmentation via partial aortic occlusion in acute ischemic stroke. J Cardiovasc Surg (Torino) 49:715-721
14. Copen WA, Rezai Gharai L, Barak ER et al (2009) Existence of the diffusion-perfusion mismatch within 24 hours after onset of acute stroke: dependence on proximal arterial occlusion. Radiology 250:878-886
15. Jovin TG, Yonas H, Gebel JM et al (2003) The cortical ischemic core and not the consistently present penumbra is a determinant of clinical outcome in acute middle cerebral artery occlusion. Stroke 34:2426-2433