Involvement of histamine 1 receptor in seizure susceptibility and neuroprotection in immature mice

Epilepsy Research

Volumn 90, Issue 1-2, 2010, Pages 8-15

  Kukko Lukjanov, Tiina Kaisa ^a   Lintunen, Minnamaija ^b,d   Jalava, Niina ^a   Laurén, Hanna B ^a,c   Lopez Picon, Francisco R ^a   Michelsen, Kimmo A ^b   Panula, Pertti ^d   Holopainen, Irma E ^a,c  

^a UNIVERSITY OF TURKU   (Finland)

^b ÅBO AKADEMI UNIVERSITY   (Finland)

^c UNIVERSITY OF TURKU   (Finland)

^d UNIVERSITY OF HELSINKI   (Finland)

Author keywords

Behavioral seizures; Developing mouse; Epilepsy; Histamine 1 (H1) receptor; Neurodegeneration; Neuroprotection

Indexed keywords

HISTAMINE H1 RECEPTOR; KAINIC ACID; TRIPROLIDINE; FLUORESCEIN DERIVATIVE; FLUORO JADE; HISTAMINE H1 RECEPTOR ANTAGONIST; ORGANIC COMPOUND;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN CORTEX; CONTROLLED STUDY; DISEASE DURATION; DISEASE PREDISPOSITION; DISEASE SEVERITY; HIPPOCAMPUS; IMMATURITY; KNOCKOUT MOUSE; MOUSE; NERVE CELL LESION; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; SEIZURE; SEPTUM PELLUCIDUM; THALAMUS; WILD TYPE; ANIMAL; BRAIN; C57BL MOUSE; CELL COUNT; CHEMICALLY INDUCED; CHI SQUARE DISTRIBUTION; DEFICIENCY; DIAGNOSTIC USE; DISEASE MODEL; DOSE RESPONSE; GENETICS; METABOLISM; NEWBORN; PATHOLOGY; PATHOPHYSIOLOGY; PROCEDURES; SEIZURES;

ANIMALS; ANIMALS, NEWBORN; BRAIN; CELL COUNT; CHI-SQUARE DISTRIBUTION; DISEASE MODELS, ANIMAL; DISEASE SUSCEPTIBILITY; DOSE-RESPONSE RELATIONSHIP, DRUG; HISTAMINE H1 ANTAGONISTS; KAINIC ACID; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; ORGANIC CHEMICALS; RECEPTORS, HISTAMINE H1; SEIZURES; TRIPROLIDINE; FLUORESCEINS;

EID: 77953541441     PISSN: 09201211     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.eplepsyres.2010.02.012     Document Type: Article

References (45)

1. Avoli M., D'Antuono M., Louvel J., Köhling R., Biagini G., Pumain R., D'Arcangelo G., Tancredi V. Network and pharmacological mechanisms leading to epileptiform synchronization in the limbic system in vitro. Prog. Neurobiol. 2002, 68:167-207.
2. Benkovic S.A., O'Callaghan J.P., Miller D.B. Sensitive indicators of injury reveal hippocampal damage in C57BL/6J mice treated with kainic acid in the absence of tonic-clonic seizures. Brain Res. 2004, 1024:59-76.
3. Benkovic S.A., O'Callaghan J.P., Miller D.B. Regional neuropathology following kainic acid intoxication in adult and aged C57BL/6J mice. Brain Res. 2006, 1070:215-231.
4. Borges K., Gearing M., McDermott D.L., Smith A.B., Almonte A.G., Wainer B.H., Dingledine R. Neuronal and glial pathological changes during epileptogenesis in the mouse pilocarpine model. Exp. Neurol. 2003, 182:21-34.
5. Chen C., Hanson E., Watson J.W., Lee J.S. P-glycoprotein limits the brain penetration of nonsedating but not sedating H1-antagonists. Drug Metab. Dispos. 2003, 31:312-318.
6. Chen Z., Li W.D., Zhu L.J., Shen Y.J., Wei E.Q. Effects of histidine, a precursor of histamine, on pentylenetetrazole-induced seizures in rats. Acta Pharmacol. Sin. 2002, 23:361-366.
7. Chen Z., Li Z., Sakurai E., Mobarakeh J.I., Ohtsu H., Watanabe T., Iinuma K., Yanai K. Chemical kindling induced by pentylenetetrazol in histamine H(1) receptor gene knockout mice (H(1)KO), histidine decarboxylase-deficient mice (HDC(-S/-S)) and mast cell-deficient W/W(v) mice. Brain Res. 2003, 968:162-166.
8. Dai H., Kaneko K., Kato H., Fujii S., Jing Y., Xu A., Sakurai E., Kato M., Okamura N., Kuramasu A., Yanai K. Selective cognitive dysfunction in mice lacking histamine H1 and H2 receptors. Neurosci. Res. 2007, 57:306-313.
9. Haas H.L., Sergeeva O.A., Selbach O. Histamine in the nervous system. Physiol. Rev. 2008, 88:1183-1241.
10. Harada C., Hirai T., Fujii Y., Harusawa S., Kurihara T., Kamei C. Intracerebroventricular administration of histamine H3 receptor antagonists decreases seizures in rat models of epilepsia. Methods Find Exp. Clin. Pharmacol. 2004, 26:263-270.
11. Hill S.J., Ganellin C.R., Timmerman H., Schwartz J.C., Shankley N.P., Young J.M., Schunack W., Levi R., Haas H.L. International Union of Pharmacology. XIII. Classification of histamine receptors. Pharmacol. Rev. 1997, 49:253-278.
12. Hirai T., Okuma C., Harada C., Mio M., Ohtsu H., Watanabe T., Kamei C. Development of amygdaloid kindling in histidine decarboxylase-deficient and histamine H1 receptor-deficient mice. Epilepsia 2004, 45:309-313.
13. Holopainen I.E. Seizures in the developing brain: cellular and molecular mechanisms of neuronal damage, neurogenesis and cellular reorganization. Neurochem. Int. 2008, 52:935-947.
14. Huang Z.L., Mochizuki T., Qu W.M., Hong Z.Y., Watanabe T., Urade Y., Hayaishi O. Altered sleep-wake characteristics and lack of arousal response to H3 receptor antagonist in histamine H1 receptor knockout mice. Proc. Natl. Acad. Sci. U.S.A. 2006, 103:4687-4692.
15. Inoue I., Taniuchi I., Kitamura D., Jenkins N.A., Gilbert D.J., Copeland N.G., Watanabe T. Characteristics of the mouse genomic histamine H1 receptor gene. Genomics 1996, 36:178-181.
16. Ishikawa T., Takechi K., Rahman A., Ago J., Matsumoto N., Murakami A., Kamei C. Influences of histamine H1 receptor antagonists on maximal electroshock seizure in infant rats. Biol. Pharm. Bull. 2007, 30:477-480.
17. Jin C., Lintunen M., Panula P. Histamine H(1) and H(3) receptors in the rat thalamus and their modulation after systemic kainic acid administration. Exp. Neurol. 2005, 194:43-56. 2005.
18. Jutel M., Watanabe T., Klunker S., Akdis M., Thomet O.A., Malolepszy J., Zak-Nejmark T., Koga R., Kobayashi T., Blaser K., Akdis C.A. Histamine regulates T-cell and antibody responses by differential expression of H1 and H2 receptors. Nature 2001, 413:420-425.
19. Kakinoki H., Ishizawa K., Fukunaga M., Fujii Y., Kamei C. The effects of histamine H3-receptor antagonists on amygdaloid kindled seizures in rats. Brain Res. Bull. 1998, 46:461-465.
20. Kamei C., Ishizawa K., Kakinoki H., Fukunaga M. Histaminergic mechanisms in amygdaloid-kindled seizures in rats. Epilepsy Res. 1998, 30:187-194.
21. Kamei C., Ohuchi M., Sugimoto Y., Okuma C. Mechanism responsible for epileptogenic activity by first-generation H1-antagonists in rats. Brain Res. 2000, 887:183-186.
22. Kienzler F., Norwood B.A., Sloviter R.S. Hippocampal injury, atrophy, synaptic reorganization, and epileptogenesis after perforant pathway stimulation-induced status epilepticus in the mouse. J. Comp. Neurol. 2009, 515:181-196.
23. Kim D., Jun K.S., Lee S.B., Kang N.G., Min D.S., Kim Y.H., Ryu S.H., Suh P.G., Shin H.S. Phospholipase C isozymes selectively couple to specific neurotransmitter receptors. Nature 1997, 389:290-293.
24. Kukko-Lukjanov T.-K., Soini S., Taira T., Michelsen K.A., Panula P., Holopainen I.E. Histaminergic neurons protect the developing hippocampus from kainic acid-induced neuronal damage in an organotypic coculture system. J. Neurosci. 2006, 26:1088-1097.
25. Lado F.A., Moshé S.L. How do seizures stop?. Epilepsia 2008, 49:1651-1664.
26. Lin J.S., Dauvilliers Y., Arnulf I., Bastuji H., Anaclet C., Parmentier R., Kocher L., Yanagisawa M., Lehert P., Ligneau X., Perrin D., Robert P., Roux M., Lecomte J.M., Schwartz J.C. An inverse agonist of the histamine H(3) receptor improves wakefulness in narcolepsy: studies in orexin -S/-Smice and patients. Neurobiol. Dis. 2008, 30:74-83.
27. Masaki T., Chiba S., Yasuda T., Noguchi H., Kakuma T., Watanabe T., Sakata T., Yoshimatsu H. Involvement of hypothalamic histamine H1 receptor in the regulation of feeding rhythm and obesity. Diabetes 2004, 53:2250-2260.
28. Matsumoto M., Nakagawa T., Inoue T., Nagata E., Tanaka K., Takano H., Minowa O., Kuno J., Sakakibara S., Yamada M., Yoneshima H., Miyawaki A., Fukuuchi Y., Furuichi T., Okano H., Mikoshiba K., Noda T. Ataxia and epileptic seizures in mice lacking type 1 inositol 1,4,5-trisphosphate receptor. Nature 1996, 379:168-171.
29. McCormick D.A., Contreras D. On the cellular and network bases of epileptic seizures. Annu. Rev. Physiol. 2001, 63:815-846.
30. Mobarakeh J.I., Sakurada S., Katsuyama S., Kutsuwa M., Kuramasu A., Lin Z.Y., Watanabe T., Hashimoto Y., Yanai K. Role of histamine H(1) receptor in pain perception: a study of the receptor gene knockout mice. Eur. J. Pharmacol. 2000, 391:81-89.
31. Müller C.J., Gröticke I., Bankstahl M., Löscher W. Behavioral and cognitive alterations, spontaneous seizures, and neuropathology developing after a pilocarpine-induced status epilepticus in C57BL/6 mice. Exp. Neurol. 2009, 219:284-297.
32. Palacios J.M., Wamsley J.K., Kuhar M.J. The distribution of histamine H1-receptors in the rat brain: an autoradiographic study. Neuroscience 1981, 6:15-37.
33. Panula P., Pirvola U., Auvinen S., Airaksinen M.S. Histamine-immunoreactive nerve fibers in the rat brain. Neuroscience 1989, 28:585-610.
34. Paxinos G., Koutcherov Y., Wang H., Halliday G.M., Watson C. Atlas of the Developing Mouse Brain 2007, Elsevier, London. 1st ed.
35. Racine R.J. Modification of seizure activity by electrical stimulation. II. Motor seizure. Electroencephalogr. Clin. Neurophysiol. 1972, 32:281-294.
36. Schauwecker P.E., Steward O. Genetic determinants of susceptibility to excitotoxic cell death: implications for gene targeting approaches. Proc. Natl. Acad. Sci. U.S.A. 1997, 94:4103-4108.
37. Schauwecker P.E. Role of genetic influences in animal models of status. Epilepsia 2007, 48:21-23.
38. Schmued L.C., Hopkins K.J. Fluoro-Jade B: a high affinity fluorescent marker for the localization of neuronal degeneration. Brain Res. 2000, 874:123-130.
39. Sturman G., Freeman P., Quinn L. Histamine H1-antagonists potentiate seizures in the EL (epilepsy-like) mouse model of temporal lobe epilepsy. Inflamm. Res. 2001, 50(Suppl. 2):S80-S81.
40. Suzuki H., Mobarakeh J.I., Nunoki K., Sukegawa J., Watanabe H., Kuramasu A., Watanabe T., Yanai K., Yanagisawa T. Effects of activation of central nervous histamine receptors in cardiovascular regulation; studies in H(1) and H(2) receptor gene knockout mice. Naunyn Schmiedebergs Arch. Pharmacol. 2005, 371:99-106.
41. Takahashi K., Lin J.S., Sakai K. Neuronal activity of histaminergic tuberomammillary neurons during wake-sleep states in the mouse. J. Neurosci. 2006, 26:10292-10298.
42. Timofeev I., Steriade M. Neocortical seizures: initiation, development and cessation. Neuroscience 2004, 123:299-336.
43. Wettschureck N., van der Stelt M., Tsubokawa H., Krestel H., Moers A., Petrosino S., Schüstz G., Di Marzo V., Offermanns S. Forebrain-specific inactivation of Gq/G11 family G proteins results in age-dependent epilepsy and impaired endocannabinoid formation. Mol. Cell. Biol. 2006, 15:5888-5894.
44. Yanai K., Watanabe T., Hatazawa J., Itoh M., Nunoki K., Hatano K., Iwata R., Ishiwata K., Ido T., Matsuzawa T. Visualization of histamine H1 receptors in dog brain by positron emission tomography. Neurosci. Lett. 1990, 118:41-44.
45. Yokoyama H., Sato M., Iinuma K., Onodera K., Watanabe T. Centrally acting histamine H1 antagonists promote the development of amygdala kindling in rats. Neurosci. Lett. 1996, 217:194-196.