Intracerebroventricular administration of histamine H3 receptor antagonists decreases seizures in rat models of epilepsia

Methods and Findings in Experimental and Clinical Pharmacology

Volumn 26, Issue 4, 2004, Pages 263-270

  Harada, C ^a   Hirai, T ^a   Fujii, Y ^a   Harusawa, S ^b   Kurihara, T ^b   Kamei, C ^a  

^a OKAYAMA UNIVERSITY   (Japan)

^b OSAKA MEDICAL COLLEGE   (Japan)

Author keywords

Amygdaloid kindled seizures; Behavior; Electroencephalogram; Histamine H 3 antagonists; Maximal electroshock seizures

Indexed keywords

CLOBENPROPIT; HISTAMINE H3 RECEPTOR ANTAGONIST; IODOPHENPROPIT; PENTOBARBITAL; THIOPERAMIDE; UNCLASSIFIED DRUG; VUF 4929; VUF 5514; VUF 5515;

AFTERDISCHARGE; AMYGDALOID NUCLEUS; ANIMAL EXPERIMENT; ANIMAL MODEL; APPARATUS; ARTICLE; CLONIC SEIZURE; CONTROLLED STUDY; DOSE RESPONSE; DRUG ACTIVITY; DRUG INHIBITION; ELECTRIC SHOCK; ELECTRODE; ELECTROENCEPHALOGRAM; EPILEPSY; MALE; NONHUMAN; RAT; SEIZURE; TONIC SEIZURE;

AMYGDALA; ANIMALS; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTROENCEPHALOGRAPHY; ELECTROSHOCK; EPILEPSY, TONIC-CLONIC; HISTAMINE AGONISTS; HISTAMINE ANTAGONISTS; IMIDAZOLES; INJECTIONS, INTRAVENTRICULAR; ISOTHIURONIUM; KINDLING, NEUROLOGIC; LATERAL VENTRICLES; MALE; METHYLHISTAMINES; PIPERIDINES; RATS; RATS, WISTAR; RECEPTORS, HISTAMINE H3; SEIZURES; THIOUREA;

EID: 2642525928     PISSN: 03790355     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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