Comparison of the efficiencies of three neural induction protocols in human adipose stromal cells

Neurochemical Research

Volumn 35, Issue 4, 2010, Pages 572-579

  Qian, Dong Xiang ^a,b   Zhang, Hong Tian ^a,c   Ma, Xu ^a,d   Jiang, Xiao Dan ^a   Xu, Ru Xiang ^a,c  

^a SOUTHERN MEDICAL UNIVERSITY   (China)

^b GUANGZHOU MEDICAL UNIVERSITY   (China)

^c CHINESE PLA GENERAL HOSPITAL   (China)

^d GUANGDONG PROVINCIAL HOSPITAL OF CHINESE MEDICINE   (China)

Author keywords

Mesenchymal stem cells; Nerve growth factors; Neural differentiation; Transdifferentiation

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; MESSENGER RNA; NERVE GROWTH FACTOR; NEUROTROPHIC FACTOR; NEUROTROPHIN 3; NEUROTROPHIN 4; REAGENT;

ADIPOSE TISSUE CELL; ANIMAL CELL; ANIMAL CELL CULTURE; APOPTOSIS; ARTICLE; CELL VIABILITY; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; IMMUNOCYTOCHEMISTRY; IMMUNOHISTOCHEMISTRY; NERVE CELL DIFFERENTIATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REAL TIME POLYMERASE CHAIN REACTION; STEM CELL; STROMA CELL; WESTERN BLOTTING;

ADIPOSE TISSUE; ANIMALS; BASE SEQUENCE; BIOLOGICAL MARKERS; BRAIN-DERIVED NEUROTROPHIC FACTOR; CELL DIFFERENTIATION; CELLS, CULTURED; CULTURE MEDIA, SERUM-FREE; DNA PRIMERS; ENZYME-LINKED IMMUNOSORBENT ASSAY; IMMUNOHISTOCHEMISTRY; IN SITU NICK-END LABELING; NERVE GROWTH FACTOR; NEURONS; RATS; RATS, SPRAGUE-DAWLEY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; STROMAL CELLS;

EID: 77953540858     PISSN: 03643190     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11064-009-0101-y     Document Type: Article

References (38)

1. Kingham PJ, Kalbermatten DF, Mahay D, Armstrong SJ, Wiberg M, Terenghi G (2007) Adipose-derived stem cells differentiate into a Schwann cell phenotype and promote neurite outgrowth in vitro. Exp Neurol 207(2):267-274
2. Gimble JM, Guilak F (2003) Differentiation potential of adipose derived adult stem (ADAS) cells. Curr Top Dev Biol 58:137-160
3. Strem BM, Hicok KC, Zhu M, Wulur I, Alfonso Z, Schreiber RE et al (2005) Multipotential differentiation of adipose tissuederived stem cells. Keio J Med 54(3):132-141
4. Ning H, Lin G, Lue TF, Lin CS (2006) Neuron-like differentiation of adipose tissue-derived stromal cells and vascular smooth muscle cells. Differentiation 74(9-10):510-518
5. Huang T, He D, Kleiner G, Kuluz J (2007) Neuron-like differentiation of adipose-derived stem cells from infant piglets in vitro. J Spinal Cord Med 30(Suppl 1):S35-S40
6. Kang SK, Putnam LA, Ylostalo J, Popescu IR, Dufour J, Belousov A et al (2004) Neurogenesis of Rhesus adipose stromal cells. J Cell Sci 117(Pt 18):4289-4299
7. Woodbury D, Schwarz EJ, Prockop DJ, Black IB (2000) Adult rat and human bone marrow stromal cells differentiate into neurons. J Neurosci Res 61(4):364-370
8. Jiang Y, Jahagirdar BN, Reinhardt RL, Schwartz RE, Keene CD, Ortiz-Gonzalez XR et al (2002) Pluripotency of mesenchymal stem cells derived from adult marrow. Nature 418(6893):41-49
9. Jiang Y, Henderson D, Blackstad M, Chen A, Miller RF, Verfaillie CM (2003) Neuroectodermal differentiation from mouse multipotent adult progenitor cells. Proc Natl Acad Sci USA 100(Suppl 1):11854-11860
10. Hermann A, Gastl R, Liebau S, Popa MO, Fiedler J, Boehm BO et al (2004) Efficient generation of neural stem cell-like cells from adult human bone marrow stromal cells. J Cell Sci 117(Pt 19): 4411-4422
11. Wislet-Gendebien S, Leprince P, Moonen G, Rogister B (2003) Regulation of neural markers nestin and GFAP expression by cultivated bone marrow stromal cells. J Cell Sci 116(Pt 16):3295-3302
12. Wislet-Gendebien S, Hans G, Leprince P, Rigo JM, Moonen G, Rogister B (2005) Plasticity of cultured mesenchymal stem cells: switch from nestin-positive to excitable neuron-like phenotype. Stem Cells 23(3):392-402
13. Sanchez-Ramos J, Song S, Cardozo-Pelaez F, Hazzi C, Stedeford T, Willing A et al (2000) Adult bone marrow stromal cells differentiate into neural cells in vitro. Exp Neurol 164(2):247-256
14. Kohyama J, Abe H, Shimazaki T, Koizumi A, Nakashima K, Gojo S et al (2001) Brain from bone: efficient "meta-differentiation" of marrow stroma-derived mature osteoblasts to neurons with Noggin or a demethylating agent. Differentiation 68(4-5):235-244
15. Tseng PY, Chen CJ, Sheu CC, Yu CW, Huang YS (2007) Spontaneous differentiation of adult rat marrow stromal cells in a long-term culture. J Vet Med Sci 69(2):95-102
16. Wagers AJ, Christensen JL, Weissman IL (2002) Cell fate determination from stem cells. Gene Ther 9(10):606-612
17. Alvarez-Dolado M, Pardal R, Garcia-Verdugo JM, Fike JR, Lee HO, Pfeffer K et al (2003) Fusion of bone-marrow-derived cells with Purkinje neurons, cardiomyocytes and hepatocytes. Nature 425(6961):968-973
18. Weimann JM, Charlton CA, Brazelton TR, Hackman RC, Blau HM (2003) Contribution of transplanted bone marrow cells to Purkinje neurons in human adult brains. Proc Natl Acad Sci USA 100(4):2088-2093
19. Castro RF, Jackson KA, Goodell MA, Robertson CS, Liu H, Shine HD (2002) Failure of bone marrow cells to transdifferentiate into neural cells in vivo. Science 297(5585):1299
20. Ono K, Yoshihara K, Suzuki H, Tanaka KF, Takii T, Onozaki K et al (2003) Preservation of hematopoietic properties in transplanted bone marrow cells in the brain. J Neurosci Res 72(4):503-507
21. Li N, Yang H, Lu L, Duan C, Zhao C, Zhao H (2007) Spontaneous expression of neural phenotype and NGF, TrkA, TrkB genes in marrow stromal cells. Biochem Biophys Res Commun 356(3):561-568
22. Yaghoobi MM, Mahani MT (2008) NGF and BDNF expression drop off in neurally differentiated bone marrow stromal stem cells. Brain Res 1203:26-31
23. Levi-Montalcini R, Skaper SD, Dal Toso R, Petrelli L, Leon A (1996) Nerve growth factor: from neurotrophin to neurokine. Trends Neurosci 19(11):514-520
24. Barbacid M (1995) Neurotrophic factors and their receptors. Curr Opin Cell Biol 7(2):148-155
25. Zhang HT, Luo J, Sui LS, Ma X, Yan ZJ, Lin JH et al (2009) Effects of differentiated versus undifferentiated adipose tissuederived stromal cell grafts on functional recovery after spinal cord contusion. Cell Mol Neurobiol
26. Zhang HT, Cheng HY, Zhang L, Fan J, Chen YZ, Jiang XD et al (2009) Umbilical cord blood cell-derived neurospheres differentiate into Schwann-like cells. Neuroreport 20(4):354-359
27. Bunnell BA, Ylostalo J, Kang SK (2006) Common transcriptional gene profile in neurospheres-derived from pATSCs, pBMSCs, and pNSCs. Biochem Biophys Res Commun 343(3):762-771
28. Lu P, Blesch A, Tuszynski MH (2004) Induction of bone marrow stromal cells to neurons: differentiation, transdifferentiation, or artifact? J Neurosci Res 77(2):174-191
29. Neuhuber B, Gallo G, Howard L, Kostura L, Mackay A, Fischer I (2004) Reevaluation of in vitro differentiation protocols for bone marrow stromal cells: disruption of actin cytoskeleton induces rapid morphological changes and mimics neuronal phenotype. J Neurosci Res 77(2):192-204
30. Croft AP, Przyborski SA (2006) Formation of neurons by nonneural adult stem cells: potential mechanism implicates an artifact of growth in culture. Stem Cells 24(8):1841-1851
31. Chen Q, Long Y, Yuan X, Zou L, Sun J, Chen S et al (2005) Protective effects of bone marrow stromal cell transplantation in injured rodent brain: synthesis of neurotrophic factors. J Neurosci Res 80(5):611-619
32. Lu P, Tuszynski MH (2005) Can bone marrow-derived stem cells differentiate into functional neurons? Exp Neurol 193(2):273-278
33. Yuen EC, Mobley WC (1996) Therapeutic potential of neurotrophic factors for neurological disorders. Ann Neurol 40(3):346-354
34. Crigler L, Robey RC, Asawachaicharn A, Gaupp D, Phinney DG (2006) Human mesenchymal stem cell subpopulations express a variety of neuro-regulatory molecules and promote neuronal cell survival and neuritogenesis. Exp Neurol 198(1):54-64
35. Ye M, Chen S, Wang X, Qi C, Lu G, Liang L et al (2005) Glial cell line-derived neurotrophic factor in bone marrow stromal cells of rat. Neuroreport 16(6):581-584
36. Yang HJ, Yang XY, Ba YC, Pang JX, Meng BL, Lin N et al (2009) Role of Neurotrophin 3 in spinal neuroplasticity in rats subjected to cord transection. Growth Factors 27(4):237-246
37. Rehman J, Traktuev D, Li J, Merfeld-Clauss S, Temm-Grove CJ, Bovenkerk JE et al (2004) Secretion of angiogenic and antiapoptotic factors by human adipose stromal cells. Circulation 109:1292-1298
38. Qu R, Li Y, Gao Q, Shen L, Zhang J, Liu Z et al (2007) Neurotrophic and growth factor gene expression profiling of mouse bone marrow stromal cells induced by ischemic brain extracts. Neuropathology 27:355-363