A case of hydroxychloroquine induced acute generalized exanthematous pustulosis confirmed by accidental oral provocation

Annals of Dermatology

Volumn 22, Issue 1, 2010, Pages 102-105

  Park, Jae Jeong ^a   Yun, Sook Jung ^a   Lee, Jee Bum ^a   Kim, Seong Jin ^a   Won, Young Ho ^a   Lee, S C ^a  

^a Chonnam National University Medical School   (South Korea)

Author keywords

Acute generalized exanthematous pustulosis; Adverse drug reactions; Hydroxychloroquine; Provocation test

Indexed keywords

EID: 77953519670     PISSN: 10139087     EISSN: None     Source Type: Journal    
DOI: 10.5021/ad.2010.22.1.102     Document Type: Article

References (12)

1. Arroyo MP, Heller P, Pomeranz MK. Generalized pustules in a healthy woman. J Drugs Dermatol 2002;1:63-65.
2. Sidoroff A, Halevy S, Bavinck JN, Vaillant L, Roujeau JC. Acute generalized exanthematous pustulosis (AGEP)-a clinical reaction pattern. J Cutan Pathol 2001;28:113-119. (Pubitemid 32112994)
3. Paradisi A, Bugatti L, Sisto T, Filosa G, Ameno PL, Capizzi R. Acute generalized exanthematous pustulosis induced by hydroxychloroquine: three cases and a review of the literature. Clin Ther 2008;30:930-940. (Pubitemid 351799876)
4. Mackenzie AH. Pharmacologic actions of 4-aminoquinoline compounds. Am J Med 1983;75:5-10.
5. Choi JH, Sim HS, Jung Y, Lee SK. A case of acute generalized exanthematous pustulosis induced by hydroxychloroquine. Korean J Dermatol 2008;46:138-140.
6. Baker H, Ryan TJ. Generalized pustular psoriasis. A clinical and epidemiological study of 104 cases. Br J Dermatol 1968;80:771-793.
7. Beylot C, Bioulac P, Doutre MS. Acute generalized exanthematic pustuloses (four cases). Ann Dermatol Venereol 1980;107:37-48. (Pubitemid 10061855)
8. Gebhardt M, Lustig A, Bocker T, Wollina U. Acute generalized exanthematous pustulosis (AGEP): manifestation of drug allergy to propicillin. Contact Dermatitis 1995;33: 204-205.
9. Braun-Falco O, Luderschmidt C, Maciejewski W, Scherer R. Generalized acute pustulosis. An unusual presentation of leukocytoclastic vasculitis. Hautarzt 1978;29:371-377.
10. Burrows NP, Russell Jones RR. Pustular drug eruptions: a histopathological spectrum. Histopathology 1993;22:569-573.
11. Plaquenil (hydroxychloroquine sulfate) tablets. Adverse reactions [Internet]. Bridgewater (NJ): Sanofi; 2006 Oct 5. Available from: http://www.accessdata.fda.gov/drugsatfda-docs/label/2007/009768s041.lbl.pdf.
12. Das J, Mandai AC. A study of drug eruptions by provocative tests. Indian J Dermatol Venereol Leprol 2001;67:238-239.