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Volumn 49, Issue 6, 2010, Pages 1069-1075

Assessment of tissue fibrosis in skin biopsies from patients with systemic sclerosis employing confocal laser scanning microscopy: An objective outcome measure for clinical trials?

Author keywords

Clinical trials outcome measure; Confocal laser scanning microscopy; Fibrosis; Scleroderma; Skin collagen; Systemic sclerosis

Indexed keywords

COLLAGEN TYPE 1; COLLAGEN TYPE 3; FIBRONECTIN; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER;

EID: 77953505288     PISSN: 14620324     EISSN: 14620332     Source Type: Journal    
DOI: 10.1093/rheumatology/keq024     Document Type: Article
Times cited : (15)

References (32)
  • 1
    • 0346727461 scopus 로고    scopus 로고
    • Following the molecular pathways toward an understanding of the pathogenesis of systemic sclerosis
    • Jimenez SA, Derk CT. Following the molecular pathways toward an understanding of the pathogenesis of systemic sclerosis. Ann Intern Med 2004;140:37-50.
    • (2004) Ann Intern Med , vol.140 , pp. 37-50
    • Jimenez, S.A.1    Derk, C.T.2
  • 3
    • 77953498857 scopus 로고
    • Progressive systemic sclerosis: clinical features and pathogenesis of cutaneous involvement (scleroderma)
    • Rodnan GP. Progressive systemic sclerosis: clinical features and pathogenesis of cutaneous involvement (scleroderma). Clin Rheum 1988;18:1-13.
    • (1988) Clin Rheum , vol.18 , pp. 1-13
    • Rodnan, G.P.1
  • 4
    • 0020967346 scopus 로고
    • Cellular immune dysfunction and the pathogenesis of scleroderma
    • Jimenez SA. Cellular immune dysfunction and the pathogenesis of scleroderma. Semin Arthritis Rheum 1983;13:104-13.
    • (1983) Semin Arthritis Rheum , vol.13 , pp. 104-113
    • Jimenez, S.A.1
  • 5
    • 0035678255 scopus 로고    scopus 로고
    • Improvement in skin thickening in systemic sclerosis associated with improved survival
    • Steen VD, Medsger TA Jr. Improvement in skin thickening in systemic sclerosis associated with improved survival. Arthritis Rheum 2001;44:2828-35.
    • (2001) Arthritis Rheum , vol.44 , pp. 2828-2835
    • Steen, V.D.1    Medsger T.A., Jr.2
  • 6
    • 0033758222 scopus 로고    scopus 로고
    • Skin thickness score as a predictor and correlate of outcome in systemic sclerosis
    • Clements PJ, Hurwitz EL, Wong WK et al. Skin thickness score as a predictor and correlate of outcome in systemic sclerosis. Arthritis Rheum 2000;43:2445-54.
    • (2000) Arthritis Rheum , vol.43 , pp. 2445-2454
    • Clements, P.J.1    Hurwitz, E.L.2    Wong, W.K.3
  • 8
    • 0030786759 scopus 로고    scopus 로고
    • Skin involvement as a relevant outcome measure in clinical trials of systemic sclerosis
    • Seibold JR, McCloskey DA. Skin involvement as a relevant outcome measure in clinical trials of systemic sclerosis. Curr Opin Rheumatol 1997;9:571-5.
    • (1997) Curr Opin Rheumatol , vol.9 , pp. 571-575
    • Seibold, J.R.1    McCloskey, D.A.2
  • 9
    • 0018345789 scopus 로고
    • Skin thickness and collagen content in progressive systemic sclerosis and localized scleroderma
    • Rodnan GP, Lipinski E, Luksick J. Skin thickness and collagen content in progressive systemic sclerosis and localized scleroderma. Arthritis Rheum 1979;22: 130-40.
    • (1979) Arthritis Rheum , vol.22 , pp. 130-140
    • Rodnan, G.P.1    Lipinski, E.2    Luksick, J.3
  • 11
    • 0029048089 scopus 로고
    • Inter and intraobserver variability of total skin thickness score (modified Rodnan TSS) in systemic sclerosis
    • Clements P, Lachenbruch P, Seibold J et al. Inter and intraobserver variability of total skin thickness score (modified Rodnan TSS) in systemic sclerosis. J Rheumatol 1995;22:1281-5.
    • (1995) J Rheumatol , vol.22 , pp. 1281-1285
    • Clements, P.1    Lachenbruch, P.2    Seibold, J.3
  • 12
    • 33747874395 scopus 로고    scopus 로고
    • Durometry for the assessment of skin disease in systemic sclerosis
    • Kissin EY, Schiller AM, Gelbard RB et al. Durometry for the assessment of skin disease in systemic sclerosis. Arthritis Rheum 2006;55:603-9.
    • (2006) Arthritis Rheum , vol.55 , pp. 603-609
    • Kissin, E.Y.1    Schiller, A.M.2    Gelbard, R.B.3
  • 13
    • 45749087311 scopus 로고    scopus 로고
    • Quantification of hardness, elasticity and viscosity of the skin of patients with systemic sclerosis using a novel sensing device (Vesmeter): a proposal for a new outcome measurement procedure
    • Kuwahara Y, Shima Y, Shirayama D et al. Quantification of hardness, elasticity and viscosity of the skin of patients with systemic sclerosis using a novel sensing device (Vesmeter): a proposal for a new outcome measurement procedure. Rheumatology 2008;47:1018-24.
    • (2008) Rheumatology , vol.47 , pp. 1018-1024
    • Kuwahara, Y.1    Shima, Y.2    Shirayama, D.3
  • 14
    • 12244264813 scopus 로고    scopus 로고
    • Correlation of serum collagen I carboxyterminal telopeptide concentrations with cutaneous and pulmonary involvement in systemic sclerosis
    • Allanore Y, Borderie D, Lemaréchal H, Cherruau B, Ekindjian OG, Kahan A. Correlation of serum collagen I carboxyterminal telopeptide concentrations with cutaneous and pulmonary involvement in systemic sclerosis. J Rheumatol 2003;30:68-73.
    • (2003) J Rheumatol , vol.30 , pp. 68-73
    • Allanore, Y.1    Borderie, D.2    Lemaréchal, H.3    Cherruau, B.4    Ekindjian, O.G.5    Kahan, A.6
  • 15
    • 0024590005 scopus 로고
    • Serum type III procollagen peptide concentrations in systemic sclerosis and Raynaud's phenomenon: relationship to disease activity and duration
    • Black CM, McWhirter A, Harrison NK, Kirk JM, Laurent GJ. Serum type III procollagen peptide concentrations in systemic sclerosis and Raynaud's phenomenon: relationship to disease activity and duration. Br J Rheumatol 1989;28:98-103.
    • (1989) Br J Rheumatol , vol.28 , pp. 98-103
    • Black, C.M.1    McWhirter, A.2    Harrison, N.K.3    Kirk, J.M.4    Laurent, G.J.5
  • 16
    • 34047268711 scopus 로고    scopus 로고
    • Collagen degradation products and proinflammatory cytokines in systemic and localized scleroderma
    • Becvár R, Hulejová H, Braun M, Stork J. Collagen degradation products and proinflammatory cytokines in systemic and localized scleroderma. Folia Biol 2007;53: 66-8.
    • (2007) Folia Biol , vol.53 , pp. 66-68
    • Becvár, R.1    Hulejová, H.2    Braun, M.3    Stork, J.4
  • 17
    • 18644363395 scopus 로고    scopus 로고
    • Increased levels of amino terminal propeptide of type III procollagen are an unfavorable predictor of survival in systemic sclerosis
    • Nagy Z, Czirják L. Increased levels of amino terminal propeptide of type III procollagen are an unfavorable predictor of survival in systemic sclerosis. Clin Exp Rheumatol 2005;23:165-72.
    • (2005) Clin Exp Rheumatol , vol.23 , pp. 165-172
    • Nagy, Z.1    Czirják, L.2
  • 18
    • 0032213648 scopus 로고    scopus 로고
    • Production of cartilage oligomeric matrix protein (COMP) by cultured human dermal and synovial fibroblasts
    • Dodge GR, Hawkins D, Boesier E, Sakai L, Jimenez SA. Production of cartilage oligomeric matrix protein (COMP) by cultured human dermal and synovial fibroblasts. Osteoarthritis Cartilage 1998;6:435-40.
    • (1998) Osteoarthritis Cartilage , vol.6 , pp. 435-440
    • Dodge, G.R.1    Hawkins, D.2    Boesier, E.3    Sakai, L.4    Jimenez, S.A.5
  • 19
    • 50249149816 scopus 로고    scopus 로고
    • COMP: a candidate molecule in the pathogenesis of systemic sclerosis with a potential as a disease marker
    • Hesselstrand R, Kassner A, Heinegård D, Saxne T. COMP: a candidate molecule in the pathogenesis of systemic sclerosis with a potential as a disease marker. Ann Rheum Dis 2008;67:1242-8.
    • (2008) Ann Rheum Dis , vol.67 , pp. 1242-1248
    • Hesselstrand, R.1    Kassner, A.2    Heinegård, D.3    Saxne, T.4
  • 20
    • 33646567848 scopus 로고    scopus 로고
    • Cartilage oligomeric matrix protein is overexpressed by scleroderma dermal fibroblasts
    • Farina G, Lemaire R, Korn JH, Widom RL. Cartilage oligomeric matrix protein is overexpressed by scleroderma dermal fibroblasts. Matrix Biol 2006;25: 213-22.
    • (2006) Matrix Biol , vol.25 , pp. 213-222
    • Farina, G.1    Lemaire, R.2    Korn, J.H.3    Widom, R.L.4
  • 21
    • 61449196805 scopus 로고    scopus 로고
    • Cartilage oligomeric matrix protein expression in systemic sclerosis reveals heterogeneity of dermal fibroblast responses to transforming growth factor beta
    • Farina G, Lemaire R, Pancari P, Bayle J, Widom RL, Lafyatis R. Cartilage oligomeric matrix protein expression in systemic sclerosis reveals heterogeneity of dermal fibroblast responses to transforming growth factor beta. Ann Rheum Dis 2009;68:435-41.
    • (2009) Ann Rheum Dis , vol.68 , pp. 435-441
    • Farina, G.1    Lemaire, R.2    Pancari, P.3    Bayle, J.4    Widom, R.L.5    Lafyatis, R.6
  • 22
    • 33750952919 scopus 로고    scopus 로고
    • Myofibroblasts and hyalinized collagen as markers of skin disease in systemic sclerosis
    • Kissin EY, Merkel PA, Lafyatis R. Myofibroblasts and hyalinized collagen as markers of skin disease in systemic sclerosis. Arthritis Rheum 2006;54:3655-60.
    • (2006) Arthritis Rheum , vol.54 , pp. 3655-3660
    • Kissin, E.Y.1    Merkel, P.A.2    Lafyatis, R.3
  • 23
    • 0018887574 scopus 로고
    • Subcommittee for Scleroderma Criteria of the American Rheumatism Association Diagnostic and Therapeutic Criteria, Committee., Preliminary criteria for the classification of systemic sclerosis, (scleroderma)
    • Subcommittee for Scleroderma Criteria of the American Rheumatism Association Diagnostic and Therapeutic Criteria Committee. Preliminary criteria for the classification of systemic sclerosis (scleroderma). Arthritis Rheum 1980;23:581-90.
    • (1980) Arthritis Rheum , vol.23 , pp. 581-590
  • 24
    • 0023854176 scopus 로고
    • Scleroderma (systemic sclerosis): classification, subsets and pathogenesis
    • LeRoy EC, Black C, Fleischmajer R et al. Scleroderma (systemic sclerosis): classification, subsets and pathogenesis. J Rheumatol 1988;15:202-5.
    • (1988) J Rheumatol , vol.15 , pp. 202-205
    • LeRoy, E.C.1    Black, C.2    Fleischmajer, R.3
  • 25
  • 26
    • 34247264458 scopus 로고    scopus 로고
    • In vitro evidence for a direct antifibrotic role 1074 www.rheumatology.oxfordjournals.org of the immunosuppressive drug mycophenolate mofetil
    • Roos N, Poulalhon N, Farge D, Madelaine I, Mauviel A, Verrecchia F. In vitro evidence for a direct antifibrotic role 1074 www.rheumatology.oxfordjournals.org of the immunosuppressive drug mycophenolate mofetil. J Pharmacol Exp Ther 2007;321:583-9.
    • (2007) J Pharmacol Exp Ther , vol.321 , pp. 583-589
    • Roos, N.1    Poulalhon, N.2    Farge, D.3    Madelaine, I.4    Mauviel, A.5    Verrecchia, F.6
  • 27
    • 39449103902 scopus 로고    scopus 로고
    • Effect of mycophenolate mofetil on pulmonary function in scleroderma-associated interstitial lung disease
    • Gerbino AJ, Goss CH, Molitor JA. Effect of mycophenolate mofetil on pulmonary function in scleroderma-associated interstitial lung disease. Chest 2008;133:455-60.
    • (2008) Chest , vol.133 , pp. 455-460
    • Gerbino, A.J.1    Goss, C.H.2    Molitor, J.A.3
  • 28
    • 36349014858 scopus 로고    scopus 로고
    • Use of mycophenolate mofetil to treat scleroderma-associated interstitial lung disease
    • Zamora AC, Wolters PJ, Collard HR et al. Use of mycophenolate mofetil to treat scleroderma-associated interstitial lung disease. Respir Med 2008; 102:150-5.
    • (2008) Respir Med , vol.102 , pp. 150-155
    • Zamora, A.C.1    Wolters, P.J.2    Collard, H.R.3
  • 30
    • 33746437403 scopus 로고    scopus 로고
    • Mycophenolate mofetil as first-line treatment improves clinically evident early scleroderma lung disease
    • Liossis SN, Bounas A, Andonopoulos AP. Mycophenolate mofetil as first-line treatment improves clinically evident early scleroderma lung disease. Rheumatology 2006;45: 1005-8.
    • (2006) Rheumatology , vol.45 , pp. 1005-1008
    • Liossis, S.N.1    Bounas, A.2    Andonopoulos, A.P.3
  • 31
    • 33847394965 scopus 로고    scopus 로고
    • Mycophenolate mofetil in diffuse cutaneous systemic sclerosis-a retrospective analysis
    • Nihtyanova SI, Brough GM, Black CM, Denton CP. Mycophenolate mofetil in diffuse cutaneous systemic sclerosis-a retrospective analysis. Rheumatology 2007; 46:442-5.
    • (2007) Rheumatology , vol.46 , pp. 442-445
    • Nihtyanova, S.I.1    Brough, G.M.2    Black, C.M.3    Denton, C.P.4
  • 32
    • 75649109604 scopus 로고    scopus 로고
    • A prospective open-label study of mycophenolate mofetil for the treatment of diffuse systemic sclerosis
    • Derk CT, Grace E, Shenin M, Naik M, Schulz S, Xiong W. A prospective open-label study of mycophenolate mofetil for the treatment of diffuse systemic sclerosis. Rheumatology 2009;48:1595-9.
    • (2009) Rheumatology , vol.48 , pp. 1595-1599
    • Derk, C.T.1    Grace, E.2    Shenin, M.3    Naik, M.4    Schulz, S.5    Xiong, W.6


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