-
1
-
-
0347993913
-
-
T. J. Guzik, R. Korbut, T. Adamek-Guzik, J. Physiol. Pharmacol. 2003, 54, 469-487.
-
(2003)
J. Physiol. Pharmacol.
, vol.54
, pp. 469-487
-
-
Guzik, T.J.1
Korbut, R.2
Adamek-Guzik, T.3
-
2
-
-
34547673497
-
-
C. Szabó, H. Ischiropoulos, R. Radi, Nat. Rev. Drug Discovery 2007, 6, 662-680.
-
(2007)
Nat. Rev. Drug Discovery
, vol.6
, pp. 662-680
-
-
Szabó, C.1
Ischiropoulos, H.2
Radi, R.3
-
4
-
-
0036561562
-
-
b) D. Salvemini, D. Riley, S. Cuzzocrea, Nat. Rev. Drug Discovery 2002, 1, 367-374;
-
(2002)
Nat. Rev. Drug Discovery
, vol.1
, pp. 367-374
-
-
Salvemini, D.1
Riley, D.2
Cuzzocrea, S.3
-
5
-
-
22944444837
-
-
c) B. Hauser, H. Bracht, M. Matejovic, P. Radermacher, B. Venkatesh, Crit. Care Trauma 2005, 101, 488-498;
-
(2005)
Crit. Care Trauma
, vol.101
, pp. 488-498
-
-
Hauser, B.1
Bracht, H.2
Matejovic, M.3
Radermacher, P.4
Venkatesh, B.5
-
6
-
-
0142247078
-
-
d) C. Muscoli, S. Cuzzocrea, D. P. Riley, J. L. Zweier, C. Thiemermann, Z. Q. Wang, D. Salvemini, Br. J. Pharmacol. 2003, 140, 445-460.
-
(2003)
Br. J. Pharmacol.
, vol.140
, pp. 445-460
-
-
Muscoli, C.1
Cuzzocrea, S.2
Riley, D.P.3
Zweier, J.L.4
Thiemermann, C.5
Wang, Z.Q.6
Salvemini, D.7
-
7
-
-
0033536644
-
-
a) D. Salvemini, Z. Q. Wang, J. L. Zweier, A. Samouilov, H. Macarthur, T. P. Misko, M. G. Currie, S. Cuzzocrea, J. A. Sikorski, D. P. Riley, Science 1999, 286, 304-306;
-
(1999)
Science
, vol.286
, pp. 304-306
-
-
Salvemini, D.1
Wang, Z.Q.2
Zweier, J.L.3
Samouilov, A.4
Macarthur, H.5
Misko, T.P.6
Currie, M.G.7
Cuzzocrea, S.8
Sikorski, J.A.9
Riley, D.P.10
-
8
-
-
33751288381
-
-
b) D. Salvemini, T. M. Doyle, S. Cuzzocrea, Biochem. Soc. Trans. 2006, 34, 965-970;
-
(2006)
Biochem. Soc. Trans.
, vol.34
, pp. 965-970
-
-
Salvemini, D.1
Doyle, T.M.2
Cuzzocrea, S.3
-
9
-
-
0036022636
-
-
c) E. Masini, S. Cuzzocrea, E. Mazzon, C. Marzocca, P. F. Mannaioni, D. Salvemini, Br. J. Pharmacol. 2002, 136, 905-917;
-
(2002)
Br. J. Pharmacol.
, vol.136
, pp. 905-917
-
-
Masini, E.1
Cuzzocrea, S.2
Mazzon, E.3
Marzocca, C.4
Mannaioni, P.F.5
Salvemini, D.6
-
10
-
-
4143093963
-
-
d) C. Di Filippo, S. Cuzzocrea, R. Marfella, V. Fabbroni, G. Scollo, L. Berrino, D. Giugliano, F. Rossi, M. D'Amico, Eur. J. Pharmacol. 2004, 497, 65-74;
-
(2004)
Eur. J. Pharmacol.
, vol.497
, pp. 65-74
-
-
Di Filippo, C.1
Cuzzocrea, S.2
Marfella, R.3
Fabbroni, V.4
Scollo, G.5
Berrino, L.6
Giugliano, D.7
Rossi, F.8
D'Amico, M.9
-
11
-
-
0035146709
-
-
e) D. Salvemini, E. Mazzon, L. Dugo, D. P. Riley, I. Serraino, A. P. Caputi, S. Cuzzocrea, Br. J. Pharmacol. 2001, 132, 19-29.
-
(2001)
Br. J. Pharmacol.
, vol.132
, pp. 19-29
-
-
Salvemini, D.1
Mazzon, E.2
Dugo, L.3
Riley, D.P.4
Serraino, I.5
Caputi, A.P.6
Cuzzocrea, S.7
-
12
-
-
33845434556
-
-
a) M. R. Filipović, D. Stanić, S. Raičević, M. Spasić, V. Niketić, Free Radical Res. 2007, 41, 62-72;
-
(2007)
Free Radical Res.
, vol.41
, pp. 62-72
-
-
Filipović, M.R.1
Stanić, D.2
Raičević, S.3
Spasić, M.4
Niketić, V.5
-
13
-
-
77953506690
-
-
b) M. R. Filipović, K. Duerr, M. Mojović, V. Simeunović, R. Zimmermann, V. Niketić, I. Ivanović- Burmazović, Angew. Chem. 2008, 120, 8863-8867;
-
(2008)
Angew. Chem.
, vol.120
, pp. 8863-8867
-
-
Filipović, M.R.1
Duerr, K.2
Mojović, M.3
Simeunović, V.4
Zimmermann, R.5
Niketić, V.6
Ivanović-Burmazović, I.7
-
14
-
-
55249091126
-
-
Angew. Chem. Int. Ed. 2008, 47, 8735-8739.
-
(2008)
Angew. Chem. Int. Ed.
, vol.47
, pp. 8735-8739
-
-
-
15
-
-
34247168484
-
-
II complexes of this class are all present as diaqua species (for solution property and stability of manganese(II) pentaazamacrocyclic complexes see: A. Dees, A. Zahl, R. Puchta, N. J. R. van Eikema Hommes, F. W. Heinemann, I. Ivanovic-Burmazovic, Inorg. Chem. 2007, 46, 2459-2470).
-
(2007)
Inorg. Chem.
, vol.46
, pp. 24592470
-
-
Dees, A.1
Zahl, A.2
Puchta, R.3
Van Eikema Hommes, N.J.R.4
Heinemann, F.W.5
Ivanovic-Burmazovic, I.6
-
16
-
-
17544404224
-
-
a) C. Bogdan, M. Röllinghoff, A. Diefenbach, Cuir. Opin. Immunol. 2000, 12, 64-76;
-
(2000)
Cuir. Opin. Immunol.
, vol.12
, pp. 64-76
-
-
Bogdan, C.1
Röllinghoff, M.2
Diefenbach, A.3
-
18
-
-
49049112285
-
-
C. Amatore, S. Arbault, M. Guille, F. Lemaitre, Chem. Rev. 2008, 108, 2585-2621.
-
(2008)
Chem. Rev.
, vol.108
, pp. 2585-2621
-
-
Amatore, C.1
Arbault, S.2
Guille, M.3
Lemaitre, F.4
-
19
-
-
77953498678
-
-
The complex should be used at sufficiently low concentrations to present low toxicity to RAW 264.7 macrophages and exclude the detection of ROS/RNS released by apoptotic cells. Conversely, a sufficiently high concentration was needed for the effects from the Mn SOD mimic to be more apparent. These boundaries defined the experimental concentration range used in this study
-
The complex should be used at sufficiently low concentrations to present low toxicity to RAW 264.7 macrophages and exclude the detection of ROS/RNS released by apoptotic cells. Conversely, a sufficiently high concentration was needed for the effects from the Mn SOD mimic to be more apparent. These boundaries defined the experimental concentration range used in this study.
-
-
-
-
20
-
-
77953532321
-
-
Experimental details, as well as supporting text and references, are given in the Supporting Information
-
Experimental details, as well as supporting text and references, are given in the Supporting Information.
-
-
-
-
22
-
-
77953514950
-
-
The addition of cytotoxic agents will lead to metabolic dysfunction, and consequently a lower rate of MTT reduction
-
b) The addition of cytotoxic agents will lead to metabolic dysfunction, and consequently a lower rate of MTT reduction.
-
-
-
-
23
-
-
77953498943
-
-
Cells to which the mimic was added remained largely similar to the control cells Although the activation by IFN-γ and LPS of cells leads to the expression of iNOS and an increased endocytic activity, co-treatment with the mimic did not lead to any significant morphological differences in comparison with cells that had been activated in the presence of IFN-γ/LPS only
-
Cells to which the mimic was added remained largely similar to the control cells. Although the activation by IFN-γ and LPS of cells leads to the expression of iNOS and an increased endocytic activity, co-treatment with the mimic did not lead to any significant morphological differences in comparison with cells that had been activated in the presence of IFN-γ/LPS only.
-
-
-
-
24
-
-
49249083962
-
-
a) C. Amatore, S. Arbault, C. Bouton, J.C. Drapier, H. Ghandour, A. Koh, ChemBioChem 2008, 9, 1472-1480;
-
(2008)
ChemBioChem
, vol.9
, pp. 1472-1480
-
-
Amatore, C.1
Arbault, S.2
Bouton, C.3
Drapier, J.C.4
Ghandour, H.5
Koh, A.6
-
25
-
-
33645758212
-
-
b) C. Amatore, S. Arbault, C. Bouton, K. Coffi, J. C. Drapier, H. Ghandour, Y. H. Tong, ChemBioChem 2006, 7, 653-661;
-
(2006)
ChemBioChem
, vol.7
, pp. 653-661
-
-
Amatore, C.1
Arbault, S.2
Bouton, C.3
Coffi, K.4
Drapier, J.C.5
Ghandour, H.6
Tong, Y.H.7
-
26
-
-
0034564686
-
-
c) C. Amatore, S. Arbault, D. Bruce, P. de Oliveira, M. Erard, M. Vuillaume, Faraday Discuss. 2000, 116, 319-333.
-
(2000)
Faraday Discuss.
, vol.116
, pp. 319-333
-
-
Amatore, C.1
Arbault, S.2
Bruce, D.3
De Oliveira, P.4
Erard, M.5
Vuillaume, M.6
-
29
-
-
21044451423
-
-
b) J. M. Fukuto, A. S. Dutton, K. N. Houk, ChemBioChem 2005, 6, 612-619;
-
(2005)
ChemBioChem
, vol.6
, pp. 612-619
-
-
Fukuto, J.M.1
Dutton, A.S.2
Houk, K.N.3
-
30
-
-
23244465458
-
-
c) S. Lymar, V. Shafirovich, G. A. Poskrebyshev, Inorg. Chem. 2005, 44, 5212-5221;
-
(2005)
Inorg. Chem.
, vol.44
, pp. 5212-5221
-
-
Lymar, S.1
Shafirovich, V.2
Poskrebyshev, G.A.3
-
31
-
-
0041508234
-
-
d) S. Lymar, R. F. Khairutdinov, J. K. Hurst, Inorg. Chem. 2003, 42, 5259-5266;
-
(2003)
Inorg. Chem.
, vol.42
, pp. 5259-5266
-
-
Lymar, S.1
Khairutdinov, R.F.2
Hurst, J.K.3
-
32
-
-
0030249458
-
-
e) A. Denicola, B. Freeman, M. Trujillo, R. Radi, Arch. Biochem. Biophys. 1996, 333, 49-58.
-
(1996)
Arch. Biochem. Biophys.
, vol.333
, pp. 49-58
-
-
Denicola, A.1
Freeman, B.2
Trujillo, M.3
Radi, R.4
-
33
-
-
7944228943
-
-
M. N. Alvarez, L. Piacenza, F. Irigoin, G. Peluffo, R. Radi, Arch. Biochem. Biophys. 2004, 432, 222-232.
-
(2004)
Arch. Biochem. Biophys.
, vol.432
, pp. 222-232
-
-
Alvarez, M.N.1
Piacenza, L.2
Irigoin, F.3
Peluffo, G.4
Radi, R.5
-
34
-
-
0035477761
-
-
C. Amatore, S. Arbault, D. Bruce, P. de Oliveira, M. Erard, M. Vuillaume, Chem. Eur. J. 2001, 7, 4171-4179.
-
(2001)
Chem. Eur. J.
, vol.7
, pp. 4171-4179
-
-
Amatore, C.1
Arbault, S.2
Bruce, D.3
De Oliveira, P.4
Erard, M.5
Vuillaume, M.6
-
35
-
-
77953492246
-
-
- concentration
-
- concentration.
-
-
-
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