Simultaneous determination of four iridoid and secoiridoid glycosides and comparative analysis of Radix Gentianae Macrophyllae and their related substitutes by HPLC

Phytochemical Analysis

Volumn 21, Issue 4, 2010, Pages 348-354

  Cao, Xiao Yan ^a   Wang, Zhe Zhi ^a  

^a SHAANXI NORMAL UNIVERSITY   (China)

Author keywords

Column liquid chromatography; Fingerprinting; Hierarchical clustering analysis; Radix Gentianae Macrophyllae; UV detection

Indexed keywords

CHROMATOGRAPHIC ANALYSIS; COLUMN CHROMATOGRAPHY; LIQUID CHROMATOGRAPHY; PARTICLE SIZE ANALYSIS; SUGARS;

COLUMN LIQUID CHROMATOGRAPHY; COMPARATIVE ANALYZES; FINGERPRINTING; HIERARCHICAL CLUSTERING ANALYSIS; IRIDOID GLYCOSIDES; RADIX GENTIANAE MACROPHYLLAE; SECOIRIDOID GLYCOSIDES; SIMULTANEOUS DETERMINATIONS; TRADITIONAL CHINESE MEDICINE; UV DETECTION;

PARTICLE SIZE;

GENTIOPICRIN; GLYCOSIDE; IRIDOID; LOGANIC ACID; METHANOL; PHOSPHORIC ACID; SECOIRIDOID; SWEROSIDE; SWERTIAMARIN; UNCLASSIFIED DRUG; HERBACEOUS AGENT;

ACCURACY; ARTICLE; CHEMICAL COMPOSITION; CHINESE MEDICINE; COLUMN CHROMATOGRAPHY; DRUG DETERMINATION; DRUG STRUCTURE; ELUTION; GENTIANA CRASSICAULIS; GENTIANA DAHURICA; GENTIANA MACROPHYLLA; GENTIANA OFFICINALIS; GENTIANA SIPHONANTHA; GENTIANA STRAMINEA; GENTIANACEAE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; NONHUMAN; PARTICLE SIZE; PLANT ROOT; QUANTITATIVE ANALYSIS; RADIX GENTIANAE MACROPHYLLAE; SPECIES COMPARISON; CHEMISTRY; COMPARATIVE STUDY; LIMIT OF DETECTION; PROCEDURES; REPRODUCIBILITY;

GENTIANA; GENTIANA CRASSICAULIS; GENTIANA DAHURICA; GENTIANA MACROPHYLLA; GENTIANA STRAMINEA;

CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DRUGS, CHINESE HERBAL; GLYCOSIDES; LIMIT OF DETECTION; REPRODUCIBILITY OF RESULTS;

EID: 77953483102     PISSN: 09580344     EISSN: 10991565     Source Type: Journal    
DOI: 10.1002/pca.1206     Document Type: Article

References (22)

1. Basaran A, Akdemir Z, Yuruker A, Calis I. 1988. Iridoid and secoiridoid glucosides from Lonicera etrusca. Fitoterapia 59: 389-392.
2. Cao XY, Li YH, Wang ZZ. 2008. Study on HPLC fi ngerprint of Gentiana macrophylla. J Chin Med Mater 31: 498-501.
3. Chen CX, Liu ZW, Sun ZR, Song CQ, Hu ZB. 2003. Studies on anti-infl ammatory eff ect of gentiopicroside. Chin Tradit Herb Drugs 34: 814-816.
4. Chen L, Liu JC, Zhang XN, Guo YY, Xu ZH, Cao W, Sun XL, Sun WJ and Zhao MG. 2008. Down-regulation of NR2B receptors partially contributes to analgesic eff ects of gentiopicroside in persistent infl ammatory pain. Neuropharmacology 54: 1175-1181.
5. Chen QL, Shi ZY, Sun WJ. 2007. A study on HPLC fi ngerprint of Gentiana macrophylla from Shaanxi. J Northwest Univ (Natural Science Edn) 27: 253-256.
6. Committee for the Pharmacopoeia of People's Republic of China. 2005. Pharmacopoeia of P.R. China, Part 1. Chemical Industry Publishing House: Beijing; 191-192.
7. Drug Administration Bureau of China. 2000. Requirement for Studying Fingerprint of Traditional Chinese Medicine (Draft).
8. Flora of China Editoral Committee.1988. Gentianaceae dictionary of Chinese botany. In Flora of China, Vol 62, He TN (ed.). Science Press: Beijing; 23-24.
9. Kondo Y, Takano F, Hojo H. 1994. Suppression of chemically and immunologically induced hepatic injuries by gentiopicroside in mice. Planta Med 60: 414-416. (Pubitemid 24330766)
10. Kumar S, Sati OP, Semwal VD, Nautiyal M, Sati S, Takeda Y. 2000. Iridoid glycosides from Lonicera quinquelocularis. Phytochemistry 53: 499-501.
11. Kumarasamy Y, Nahar L, Cox PJ, Jaspars M, Sarker SD. 2003. Bioactivity of secoiridoid glycosides from Centaurium erythraea. Phytomedicine 10: 344-347. (Pubitemid 36597172)
12. Li XM, He XR. 2004. HPLC fi ngerprint of Gentiana straminea Maxim. Chin Tradit Pat Med 26: 4-7.
13. Liu J, Liu Y, Klaassen CD. 1994a. The eff ect of Chinese hepatoprotective medicines on experimental liver injury in mice. J Ethnopharmacol 42: 183-191. (Pubitemid 24177364)
14. Liu YH, Li X-C, Liu YQ and Yang CR. 1994b. Iridoid glycosides from Gentiana macrophylla. Acta Bot Yunnan 16: 85-89.
15. Skrzypczak L, Wesolowska M, Skrzypczak E. 1993. Gentiana species XII: in vitro culture, regeneration, and production of secoiridoid glucosides. In: Biotechnology in Agriculture and Forestry, Vol. 21, Bajaj YPS (ed.). Springer: Berlin; 172-186.
16. Sun J, Li YL, Ji LJ, Ma YH, Xu WH, Chen GC. 2006a. HPLC determination of contents of four active constituents in Tibetan medicine Gentiana straminea (Gentianaceae) during diff erent growing period. Acta Bot Yunnan 28: 219-222.
17. Sun J, Chen GC, Li YL, Zhao XE, Wang HL. 2006b. Determination of four iridoid glycosides in tibetan medicine Gentiana straminea Maxim.by HPLC. Chin J Anal Lab 25: 28-31.
18. Tan RX, Wolfender JL, Zhang LX. 1996. Acyl secoiridoids and antifungal constituents from Gentiana macrophylla. Phytochemistry 42: 1305-1313.
19. Tan RX, Kong LD, Wei HX. 1998. Secoiridoid glycosides and an antifungal anthranilate derivative from Gentiana tibetica. Phytochemistry 47: 1223-1226.
20. Wang YY, Zhao ZL, Wu JR, Wang ZT. 2009. HPLC fi ngerprint of Radix Gentianae Crassicaulis. Chin Tradit Herb Drugs 40: 121-123.
21. Wu QX, An Y, Zhang MJ, Lu YC, Bao JY, Hu SQ, Yu J. 2006. HPLC fi ngerprinting of Gentiana straminea, a traditional Chinese medicine from Qinghai province. Acta Bot Boreal - Occident Sin 26: 174-178.
22. Wu YX, Chen G, Yu CY. 2008. Chemical constituents of Gentiana straminea Maxim. J Beijing Univ Chem Tech 35: 64-67.