Primary CNS lymphoma

Therapeutic Advances in Neurological Disorders

Volumn 2, Issue 2, 2009, Pages 93-104

  Schlegel, Uwe ^a  

^a RUHR UNIVERSITY BOCHUM   (Germany)

Author keywords

Brain tumors; CNS lymphoma; Methotrexate; Non Hodgkin's lymphoma; Temozolomide

Indexed keywords

CARMUSTINE; CYTARABINE; ETOPOSIDE; FLUORODEOXYGLUCOSE F 18; HYDROCORTISONE; IBRITUMOMAB TIUXETAN; IFOSFAMIDE; LOMUSTINE; MELPHALAN; METHOTREXATE; METHYLPREDNISOLONE; PROCARBAZINE; RITUXIMAB; TEMOZOLOMIDE; TOPOTECAN; TOSITUMOMAB I 131; VINCRISTINE;

AUTOLOGOUS STEM CELL TRANSPLANTATION; CANCER CHEMOTHERAPY; CANCER DIAGNOSIS; CANCER RADIOTHERAPY; CANCER SURGERY; CLINICAL TRIAL; COMBINATION CHEMOTHERAPY; DIAGNOSTIC PROCEDURE; DRUG CLEARANCE; DRUG MEGADOSE; HIGHLY ACTIVE ANTIRETROVIRAL THERAPY; HUMAN; LYMPHOPROLIFERATIVE DISEASE; MULTIPLE CYCLE TREATMENT; NEUROIMAGING; NEUROTOXICITY; NONHODGKIN LYMPHOMA; NUCLEAR MAGNETIC RESONANCE IMAGING; POSITRON EMISSION TOMOGRAPHY; PRIMARY CENTRAL NERVOUS SYSTEM LYMPHOMA; PRIORITY JOURNAL; REVIEW; SALVAGE THERAPY; STEREOTACTIC BIOPSY;

EID: 77953472173     PISSN: 17562856     EISSN: None     Source Type: Journal    
DOI: 10.1177/1756285608101222     Document Type: Review

References (61)

1. Abrey, L.E., de Angelis, L.M. and Yahalom, J. (1998) Long-term survival in primary CNS lymphoma, J Clin Oncol 16: 859-863.
2. Abrey, L.E., Moskowitz, C.H., Mason, W.P., Crump, M., Stewart, D., Forsyth, P. et al. (2003) Intensive methotrexate and cytarabine followed by high-dose chemotherapy with autologous stem-cell rescue in patients with newly diagnosed primary CNS lymphoma: an intent-to-treat analysis, J Clin Oncol 21: 4151-4156.
3. Abrey, L.E., Batchelor, T.T., Ferreri, A.J.M., Gospodarowicz, M., Pulczynski, E.J., Zucca, E. et al. (2005) Report of an international workshop to standardize baseline evaluation and response criteria for primary CNS lymphoma, J Clin Oncol 23: 5034-5043.
4. Abrey, L.E., Ben-Porat, L., Panageas, K.S., Yahalom, J., Berkey, B., Curran, W. et al. (2006) Primary central nervous system lymphoma: the Memorial Sloan-Kettering Cancer Center prognostic model, J Clin Oncol 24: 5711-5715.
5. Antinori, A., Cingolani, A., Alba, L.R., Ammassari, A., Serraino, D., Ciancio, B.C. et al. (2001) Better response to chemotherapy and prolonged survival in AIDS-related lymphomas responding to highly active antiretroviral therapy, AIDS 15: 1483-1491.
6. Batchelor, T. and Loeffler, J.S. (2006) Primary CNS lymphoma, J Clin Oncol 24: 1281-1288.
7. Batchelor, T., Carson, K., O'Neill, A., Grossman, S.A., Alavi, J., New, P. et al. (2003) Treatment of primary CNS lymphoma with methotrexate and deferred radiotherapy: a report of NABTT 96-07, J Clin Oncol 21: 1044-1049.
8. Bellinzona, M., Roser, F., Ostertag, H., Gaab, R.M. and Saini, M. (2005) Surgical removal of primary central nervous system lymphomas (PCNSL) presenting as space occupying lesions: a series of 33 cases, Eur J Surg Oncol 31: 100-105.
9. Central Brain Tumor Registry of the United States (2005) Statistical Report: Primary Brain Tumors in the United States, 1998-2002. Central Brain Tumor Registry of the United States, Chicago, IL.
10. Correa, D.D., Maron, L., Harder, H., Klein, M., Armstrong, C.L., Calabrese, P. et al. (2007) Cognitive functions in primary central nervous system lymphoma: literature review and assessment guidelines, Ann Oncol 18: 1145-1151.
11. Courts, C., Montesinos-Rongen, M., Martin-Subero, J.I., Brunn, A., Siemer, D., Zuhlke-Jenisch, R. et al. (2007) Transcriptional profiling of the nuclear factor-kappaB pathway identifies a subgroup of primary lymphoma of the central nervous system with low BCL 10 expression, J Neuropathol Exp Neurol 66: 230-237.
12. de Angelis, L.M., Seiferheld, W., Schold, S.C., Fisher, B. and Schultz, C.J. (2002) Radiation Therapy Oncology Group Study 93-10. Combination chemotherapy and radiotherapy for primary central nervous system lymphoma: Radiation Therapy Oncology Group Study 93-10, J Clin Oncol 20: 4643-4648 III.
13. Doolittle, N.D., Jahnke, K., Belanger, R., Ryan, D.A., Nance, R.W., Lacy, C.A. et al. (2007) Potential of chemo-immunotherapy in relapsed primary central nervous system (CNS) lymphoma, Leuk Lymphoma 48: 1712-1720.
14. Ekenel, M., Iwamoto, F.M., Ben-Porat, L.S., Panageas, K.S., Yahalom, J., Deangelis, L.M. et al. (2008) Primary central nervous system lymphoma: The role of consolidation treatment after a complete response to high-dose methotrexate-based chemotherapy, Cancer 113: 1025-31.
15. Enting, R.H., Demopoulos, A., de Angelis, L.M. and Abrey, L.E. (2004) Salvage therapy for primary CNS lymphoma with a combination of rituximab and temozolomide, Neurology 63: 901-903.
16. Ferreri, A.J., Reni, M., Pasini, F., Calderoni, A., Tirelli, U., Pivnik, A. et al. (2002) A multicenter study of treatment of primary CNS lymphoma, Neurology 58: 1513-1520.
17. Fischer, L., Jahnke, K., Martus, P., Weller, M., Thiel, E. and Korfel, A. (2006) The diagnostic value of cerebrospinal fluid pleocytosis and protein in the detection of lymphomatous meningitis in primary central nervous system lymphomas, Haematologica 91: 429-430.
18. Fischer, L., Martus, P., Weller, M., Klasen, H.A., Rohden, B., Roth, A. et al. (2008) Meningeal dissemination in primary CNS lymphoma: Prospective evaluation of 282 patients, Neurology 71: 1102-1108.
19. Fischer, L., Thiel, E., Klasen, H.A., Kirchen, H., Jahnke, K. and Korfel, A. (2004) Response of relapsed or refractory primary CNS lymphoma (PCNSL) to topotecan, Neurology 62: 1885-1888.
20. Gerstner, E.R., Carson, K.A., Grossman, S.A., Mrugala, M.M., Nugent, W., Nierenberg, K. et al. (2008) Long-term outcome in PCNSL patients treated with high-dose methotrexate and deferred radiation, Neurology 70: 401-402.
21. Gleissner, B., Siehl, J., Korfel, A., Reinhardt, R. and Thiel, E. (2002) CSF evaluation in primary CNS lymphoma patients by PCR of the CDR III IgH genes, Neurology 58: 390-396.
22. Harris, N.L., Jaffe, E.S., Diebold, J., Flandrin, G., Muller-Hermelink, H.K., Vardiman, J. et al. (2000) The World Health Organization classification of neoplasms of the hematopoietic and lymphoid tissues: report of the Clinical Advisory Committee meeting - Airlie House, Virginia, November, 1997, Hematol J 1: 53-66.
23. Herrlinger, U., Küker, W., Uhl, M., Blaicher, H.P., Karnath, H.O., Kanz, L. et al. (2005) NOA-03 multicenter trial of high-dose methotrexate therapy in primary CNS lymphoma: final report, Ann Neurol 57: 843-847.
24. Hoang-Xuan, K., Taillandier, L., Chinot, O., Soubeyran, P., Bogdhan, U., Hildebrand, J. et al. (2003) Chemotherapy alone as initial treatment for primary CNS lymphoma in patients older than 60 years: a multicenter phase II study (26952) of the European Organization for Research and Treatment of Cancer Brain Tumor Group, J Clin Oncol 21: 2726-2731.
25. Hoffmann, C., Tabrizian, S., Wolf, E., Eggers, C., Stoehr, A., Plettenberg, A. et al. (2001) Survival of AIDS patients with primary central nervous system lymphoma is dramatically improved by HAARTinduced immune recovery, AIDS 15: 2119-2127.
26. Hottinger, A.F., de Angelis, L.M., Yahalom, J. and Abrey, L.E. (2007) Salvage whole brain radiotherapy for recurrent or refractory primary CNS lymphoma, Neurology 69: 1178-1182.
27. Illerhaus, G., Marks, R., Ihorst, G., Guttenberger, R., Ostertag, C., Derigs, G. et al. (2006) High-dose chemotherapy with autologous stem-cell transplantation and hyperfractionated radiotherapy as first-line treatment of primary CNS lymphoma, J Clin Oncol 24: 3865-3870.
28. Illerhaus, G., Muller, F., Feuerhake, F., Schafer, A.O., Ostertag, C., Finke, J. et al. (2008) High-dose chemotherapy and autologous stem-cell transplantation without consolidating radiotherapy as first-line treatment for primary lymphoma of the central nervous system, Haematologica 93: 147-148.
29. Iwamoto, F.M., Schwartz, J., Pandit-Taskar, N., Peak, S., Divgi, C.R., Zelenetz, A.D. et al. (2007) Study of radiolabeled indium-111 and yttrium-90 ibritumomab tiuxetan in primary central nervous system lymphoma, Cancer 110: 2528-2534.
30. Jahnke, K., Korfel, A., Martus, P., Weller, M., Herrlinger, U., Schmittel, A. et al. (2005 a) High-dose methotrexate toxicity in elderly patients with primary central nervous system lymphoma, Ann Oncol 16: 445-449.
31. Jahnke, K., Thiel, E., Schilling, A., Herrlinger, U., Weller, M., Coupland, S.E. et al. (2005 b) Low-grade primary central nervous system lymphoma in immunocompetent patients, Br J Haematol 128: 616-624.
32. Jahnke, K., Hummel, M., Korfel, A., Burmeister, T., Kiewe, P., Klasen, H.A. et al. (2006 a) Detection of subclinical systemic disease in primary CNS lymphoma by polymerase chain reaction of the rearranged immunoglobulin heavy-chain genes, J Clin Oncol 24: 4754-4757.
33. Jahnke, K., Korfel, A., Komm, J., Bechrakis, N.E., Stein, H., Thiel, E. et al. (2006 b) Intraocular lymphoma, 2000-2005: results of a retrospective multicentre trial, Graefes Arch Clin Exp Ophthalmol 244: 663-669.
34. Khan, R.B., Shi, W., Thaler, H.T., de Angelis, L.M. and Abrey, L.E. (2002) Is intrathecal methotrexate necessary in the treatment of primary CNS lymphoma? J Neurooncol 58: 175-178.
35. Kuker, W., Nägele, T., Korfel, A. et al. (2005) Primary central nervous system lymphomas (PCNSL): MRI features at presentation in 100 patients, J Neurooncol 72: 169-177.
36. Lai, R., Abrey, L.E., Rosenblum, M.K. and de Angelis, L.M. (2004) Treatment-induced leukoencephalopathy in primary CNS lymphoma: a clinical and autopsy study, Neurology 62: 451-456.
37. Mohile, N.A., de Angelis, L.M. and Abrey, L.E. (2008) The utility of body FDG PET in staging primary central nervous system lymphoma, Neuro Oncol 10: 223-228.
38. Montesinos-Rongen, M., van Roost, D., Schaller, C., Wiestler, O.D. and Deckert, M. (2004) Primary diffuse large B-cell lymphomas of the central nervous system are targeted by aberrant somatic hypermutation, Blood 103: 1869-1875.
39. Nelson, D.F., Martz, K.L., Bonner, H., Nelson, J.S., Newall, J., Kerman, M.D. et al. (1992) Non-Hodgkin's lymphoma of the brain: can high dose, large volume radiation therapy improve survival? Report on a prospective trial by the Radiation Therapy Oncology Group (RTOG): RTOG 8315, Int J Radiat Oncol Biol Phys 23: 9-17.
40. Nguyen, P.L., Chakravarti, A., Finkelstein, D.M., Hochberg, F.H., Batchelor, T.T. and Loeffler, J.S. (2005) Results of whole-brain radiation as salvage of methotrexate failure for immunocompetent patients with primary CNS lymphoma, J Clin Oncol 23: 1507-1513.
41. O'Brien, P., Roos, D., Pratt, G., Liew, K., Barton, M., Poulsen, M. et al. (2000) Phase II multicenter study of brief single-agent methotrexate followed by irradiation in primary CNS lymphoma, J Clin Oncol 18: 519-526.
42. Omuro, A.M., Ben-Porat, L.S., Panageas, K.S., Kim, A.K., Correa, D.D., Yahalom, J. et al. (2005) Delayed neurotoxicity in primary central nervous system lymphoma, Arch Neurol 62: 1595-1600.
43. Omuro, A.M., Taillandier, L., Chinot, O., Carnin, C., Barrie, M., Hoang-Xuan, K. et al. (2007) Temozolomide and methotrexate for primary central nervous system lymphoma in the elderly, J Neurooncol 85: 207-211.
44. Palmedo, H., Urbach, H., Bender, H., Schlegel U., Schmidt-Wolf, I.G., Matthies, A. et al. (2006) FDG-PET in immunocompetent patients with primary central nervous system lymphoma: correlation with MRI and clinical follow-up, Eur J Nucl Med Mol Imaging 33: 164-168.
45. Panageas, K.S., Elkin, E.B., de Angelis, L.M., Ben-Porat, L. and Abrey, L.E. (2005) Trends in survival from primary central nervous system lymphoma, 1975-1999: a population-based analysis, Cancer 104: 2466-2472.
46. Pels, H., Juergens, A., Glasmacher, A., Schulz, H., Engert, A., Linnebank, M. et al. (2009) Early relapses in primary CNS lymphoma after response to polychemotherapy without intraventricular treatment: results of a phase II study, J Neurooncol 91: 299-305.
47. Pels, H., Schmidt-Wolf, I.G., Glasmacher, A., Schulz, H., Engert, A., Diehl, V. et al. (2003 a) Primary central nervous system lymphoma: results of a pilot and phase II study of systemic and intraventricular chemotherapy with deferred radiotherapy, J Clin Oncol 21: 4489-4495.
48. Pels, H., Schulz, H., Schlegel, U. and Engert, A. (2003 b) Treatment of CNS lymphoma with the anti-CD20 antibody rituximab: experience with two cases and review of the literature, Onkologie 26: 351-354.
49. Pels, H. and Schlegel, U. (2006) Primary central nervous system lymphoma, Curr Treatment Opt Neurol 8: 346-357.
50. Plotkin, S.R., Betensky, R.A., Hochberg, F.H., Grossman, S.A., Lesser, G.J., Nabors, L.B. et al. (2004) Treatment of relapsed central nervous system lymphoma with high-dose methotrexate, Clin Cancer Res 10: 5643-5646.
51. Poortmans, P.M., Kluin-Nelemans, H.C., Haaxma-Reiche, H., Van't Veer, M., Hansen, M., Soubeyran, P. et al. (2003) High-dose methotrexate-based chemotherapy followed by consolidating radiotherapy in non-AIDS-related primary central nervous system lymphoma: European Organization for Research and Treatment of Cancer Lymphoma Group Phase II Trial20962, J Clin Oncol 21: 4483-4488 III.
52. Porter, A.B., Giannini, C., Kaufmann, T., Lucchinetti, C.F., Wu, W., Decker, P.A. et al. (2008) Primary central nervous system lymphoma can be histologically diagnosed after previous corticosteroid use: a pilot study to determine whether corticosteroids prevent the diagnosis of primary central nervous system lymphoma, Ann Neurol 63: 662-667.
53. Reni, M., Mason, W., Zaja, F., Perry, J., Franceschi, E., Bernardi, D. et al. (2004) Salvage chemotherapy with temozolomide in primary CNS lymphomas: preliminary results of a phase II trial, Eur J Cancer 40: 1682-1688.
54. Reni, M., Mazza, E., Foppoli, M. and Ferreri, A.J. (2007) Primary central nervous system lymphomas: salvage treatment after failure to high-dose methotrexate, Cancer Lett 258: 165-170.
55. Rubenstein, J.L., Fridlyand, J., Abrey, L., Shen, A., Karch, J., Wang, E. et al. (2007) Phase I study of intraventricular administration of rituximab in patients with recurrent CNS and intraocular lymphoma, J Clin Oncol 25: 1350-1356.
56. Shah, G.D., Yahalom, J., Correa, D.D., Lai, R.K., Raizer, J.J., Schiff, D. et al. (2007) Combined immunochemotherapy with reduced whole-brain radiotherapy for newly diagnosed primary CNS lymphoma, J Clin Oncol 25: 4730-4735.
57. Shenkier, T.N., Blay, J.Y., O'Neill, B.P., Poortmans, P., Thiel, E., Jahnke, K. et al. (2005) Primary CNS lymphoma of T-cell origin: a descriptive analysis from the international primary CNS lymphoma collaborative group, J Clin Oncol 23: 2233-2239.
58. Shibamoto, Y., Ogino, H., Hasegawa, M., Suzuki, K., Nishio, M., Fujii, T. et al. (2005) Results of radiation monotherapy for primary central nervous system lymphoma in the, 1990s, Int J Radiat Oncol Biol Phys 62: 809-813.
59. Smith, J.R., Rosenbaum, J.T., Wilson, D.J., Doolittle, N.D., Siegal, T., Neuwelt, E.A., et al. (2002) Role of intravitreal methotrexate in the management of primary central nervous system lymphoma with ocular involvement, Ophthalmology 109: 1709-1716.
60. Soussain, C., Hoang-Xuan, K., Taillandier, L., Fourme, E., Choquet, S., Witz, F. et al. (2008) Intensive chemotherapy followed by hematopoietic stem-cell rescue for refractory and recurrent primary CNS and intraocular lymphoma: Societe Francaise de Greffe de Moelle Osseuse-Therapie Cellulaire, J Clin Oncol 26: 2512-2518.
61. Wong, E.T. (2005) Monoclonal antibody therapy for central nervous system lymphomas: An emerging treatment paradigm, Expert Opin Pharmacother 6: 1107-1114.