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Volumn 1, Issue 2, 2009, Pages 303-312

Immunotherapeutic polyoma and human papilloma virus-like particles

Author keywords

Cancer therapy; Human papillomavirus; Immune therapy; Polyomavirus; Vaccine; Virus like particle

Indexed keywords

ANTIBODY; CANCER VACCINE; CAPSID PROTEIN; CAPSID PROTEIN L1; CAPSID PROTEIN L2; CHIMERIC PROTEIN; EPIDERMAL GROWTH FACTOR RECEPTOR 2; EPIDERMAL GROWTH FACTOR RECEPTOR 2 PROTEIN VP2 FUSION PROTEIN; EPITOPE; GLUTATHIONE TRANSFERASE PROTEIN VP1 FUSION PROTEIN; HYBRID PROTEIN; NEUTRALIZING ANTIBODY; PLACEBO; PROTEIN E6; PROTEIN E7; PROTEIN L1 E7 FUSION PROTEIN; PROTEIN L2 E7 FUSION PROTEIN; PROTEIN VP1; PROTEIN VP2; PROTEIN VP3; STREPTAVIDIN; UNCLASSIFIED DRUG; VIRUS PROTEIN; VIRUS VACCINE; WART VIRUS VACCINE;

EID: 77953452449     PISSN: 1750743X     EISSN: None     Source Type: Journal    
DOI: 10.2217/1750743X.1.2.303     Document Type: Review
Times cited : (9)

References (81)
  • 1
    • 22244459917 scopus 로고    scopus 로고
    • Gene therapy: Twenty-first century medicine
    • Verma I, Weitzman M: Gene therapy: twenty-first century medicine. Annu. Rev. Biochem. 74, 711-738 (2005).
    • (2005) Annu. Rev. Biochem. , vol.74 , pp. 711-738
    • Verma, I.1    Weitzman, M.2
  • 2
    • 33744467752 scopus 로고    scopus 로고
    • Treatment of human disease by adeno-associated viral gene transfer
    • Warrington K, Herzog R: Treatment of human disease by adeno-associated viral gene transfer. Hum. Genet. 119, 571-603 (2006).
    • (2006) Hum. Genet. , vol.119 , pp. 571-603
    • Warrington, K.1    Herzog, R.2
  • 3
    • 31144475398 scopus 로고    scopus 로고
    • Viral gene therapy strategies: From basic science to clinical application
    • DOI 10.1002/path.1896
    • Young LS, Searle PF, Onion D, Mautner V: Viral gene therapy strategies: from basic science to clinical application. J. Pathol. 208, 299-318 (2006). (Pubitemid 43126122)
    • (2006) Journal of Pathology , vol.208 , Issue.2 , pp. 299-318
    • Young, L.S.1    Searle, P.F.2    Onion, D.3    Mautner, V.4
  • 4
    • 0034159940 scopus 로고    scopus 로고
    • Gene therapy: The first decade
    • Mountain A: Gene therapy: the first decade. Trends Biotechnol. 18, 119-128 (2000).
    • (2000) Trends Biotechnol. , vol.18 , pp. 119-128
    • Mountain, A.1
  • 5
    • 33749338991 scopus 로고    scopus 로고
    • Vaccines for the prevention of human papillomavirus infections
    • Speck LM, Tyring SK: Vaccines for the prevention of human papillomavirus infections. Skin Therapy Lett. 11(6), 1-3 (2006).
    • (2006) Skin Therapy Lett. , vol.11 , Issue.6 , pp. 1-3
    • Speck, L.M.1    Tyring, S.K.2
  • 8
    • 21344434789 scopus 로고    scopus 로고
    • A single vaccination with polyomavirus VP1/VP2Her2 virus-like particles prevents outgrowth of HER-2/neu-expressing tumors
    • Demonstrates the efficiency of virus-like particles (VLPs) carrying tumor antigens as vaccines against nonviral tumors
    • Tegerstedt K, Lindencrona JA, Curcio C et al.: A single vaccination with polyomavirus VP1/VP2Her2 virus-like particles prevents outgrowth of HER-2/neu-expressing tumors. Cancer Res. 65(13), 5953-5957 (2005). ■ Demonstrates the efficiency of virus-like particles (VLPs) carrying tumor antigens as vaccines against nonviral tumors.
    • (2005) Cancer Res. , vol.65 , Issue.13 , pp. 5953-5957
    • Tegerstedt, K.1    Lindencrona, J.A.2    Curcio, C.3
  • 9
    • 4844220670 scopus 로고    scopus 로고
    • SV40 pseudovirions as highly efficient vectors for gene transfer and their potential application in cancer therapy
    • Kimchi-Sarfaty C, Gottesman MM: SV40 pseudovirions as highly efficient vectors for gene transfer and their potential application in cancer therapy. Curr. Pharm. Biotechnol. 5(5), 451-458 (2004).
    • (2004) Curr. Pharm. Biotechnol. , vol.5 , Issue.5 , pp. 451-458
    • Kimchi-Sarfaty, C.1    Gottesman, M.M.2
  • 10
    • 0034898470 scopus 로고    scopus 로고
    • Conjugation of a self-antigen to papillomavirus-like particles allows for efficient induction of protective autoantibodies
    • Demonstrates the ability to induce autoantibodies using conjugated VLPs
    • Chackerian B, Lowy DR, Schiller JT: Conjugation of a self-antigen to papillomavirus-like particles allows for efficient induction of protective autoantibodies. J. Clin. Invest. 108(3), 415-423 (2001). ■ Demonstrates the ability to induce autoantibodies using conjugated VLPs.
    • (2001) J. Clin. Invest. , vol.108 , Issue.3 , pp. 415-423
    • Chackerian, B.1    Lowy, D.R.2    Schiller, J.T.3
  • 11
    • 22544431937 scopus 로고    scopus 로고
    • A therapeutic vaccine for nicotine dependence: Preclinical efficacy, and Phase I safety and immunogenicity
    • Maurer P, Jennings GT, Willers J et al.: A therapeutic vaccine for nicotine dependence: preclinical efficacy, and Phase I safety and immunogenicity. Eur. J. Immunol. 35(7), 2031-2040 (2005).
    • (2005) Eur. J. Immunol. , vol.35 , Issue.7 , pp. 2031-2040
    • Maurer, P.1    Jennings, G.T.2    Willers, J.3
  • 12
    • 0034604711 scopus 로고    scopus 로고
    • Production of polyomavirus structural protein VP1 in yeast cells and its interaction with cell structures
    • DOI 10.1016/S0014-5793(00)01787-7, PII S0014579300017877
    • Palkova Z, Adamec T, Liebl D, Stokrova J, Forstova J: Production of polyomavirus structural protein VP1 in yeast cells and its interaction with cell structures. FEBS Lett. 478(3), 281-289 (2000). (Pubitemid 30621632)
    • (2000) FEBS Letters , vol.478 , Issue.3 , pp. 281-289
    • Palkova, Z.1    Adamec, T.2    Liebl, D.3    Stokrova, J.4    Forstova, J.5
  • 14
    • 0022549499 scopus 로고
    • Self-assembly of purified polyomavirus capsid protein VP1
    • Salunke DM, Caspar DL, Garcea RL: Self-assembly of purified polyomavirus capsid protein VP1. Cell 46(6), 895-904 (1986).
    • (1986) Cell , vol.46 , Issue.6 , pp. 895-904
    • Salunke, D.M.1    Caspar, D.L.2    Garcea, R.L.3
  • 15
    • 0035896012 scopus 로고    scopus 로고
    • Papillomavirus capsid protein expression in Escherichia coli: Purification and assembly of HPV11 and HPV16 L1
    • Chen XS, Casini G, Harrison SC, Garcea RL: Papillomavirus capsid protein expression in Escherichia coli: purification and assembly of HPV11 and HPV16 L1. J. Mol. Biol. 307(1), 173-182 (2001).
    • (2001) J. Mol. Biol. , vol.307 , Issue.1 , pp. 173-182
    • Chen, X.S.1    Casini, G.2    Harrison, S.C.3    Garcea, R.L.4
  • 17
    • 18044397111 scopus 로고    scopus 로고
    • Beneficial therapeutic effects with different particulate structures of murine polyomavirus VP1-coat protein carrying self or non-self CD8 T cell epitopes against murine melanoma
    • Brinkman M, Walter J, Grein S et al.: Beneficial therapeutic effects with different particulate structures of murine polyomavirus VP1-coat protein carrying self or non-self CD8 T cell epitopes against murine melanoma. Cancer Immunol. Immunother. 54(6), 611-622 (2005).
    • (2005) Cancer Immunol. Immunother. , vol.54 , Issue.6 , pp. 611-622
    • Brinkman, M.1    Walter, J.2    Grein, S.3
  • 18
    • 0034466906 scopus 로고    scopus 로고
    • Persistence and tissue distribution of DNA in normal and immunodeficient mice inoculated with polyomavirus VP1 pseudocapsid complexes or polyomavirus
    • Heidari S, Krauzewicz N, Kalantari M, Vlastos A, Griffin BE, Dalianis T: Persistence and tissue distribution of DNA in normal and immunodeficient mice inoculated with polyomavirus VP1 pseudocapsid complexes or polyomavirus. J. Virol. 74, 11963-11965 (2000).
    • (2000) J. Virol. , vol.74 , pp. 11963-11965
    • Heidari, S.1    Krauzewicz, N.2    Kalantari, M.3    Vlastos, A.4    Griffin, B.E.5    Dalianis, T.6
  • 19
    • 0347382530 scopus 로고    scopus 로고
    • Murine pneumotropic virus VP1 virus-like particles (VLPs) bind to several ceil types independent of sialic acid residues and do not serologically cross react with murine polyomavirus VP1 VLPs
    • Tegerstedt K, Andreasson K, Vlastos A, Hedlund KO, Dalianis T, Ramqvist T: Murine pneumotropic virus VP1 virus-like particles (VLPs) bind to several ceil types independent of sialic acid residues and do not serologically cross react with murine polyomavirus VP1 VLPs. J. Gen. Virol. 84, 3443-3452 (2003).
    • (2003) J. Gen. Virol. , vol.84 , pp. 3443-3452
    • Tegerstedt, K.1    Andreasson, K.2    Vlastos, A.3    Hedlund, K.O.4    Dalianis, T.5    Ramqvist, T.6
  • 20
    • 0032539564 scopus 로고    scopus 로고
    • Chimeric papillomavirus virus-like particles elicit antitumor immunity against the E7 oncoprotein in an HPV16 tumor model
    • Early demonstration of chimeric papillomavirus-like particles as immunogens
    • Greenstone HL, Nieland JD, de Visser KE et al.: Chimeric papillomavirus virus-like particles elicit antitumor immunity against the E7 oncoprotein in an HPV16 tumor model. Proc. Natl Acad. Sci. USA 95, 1800-1805 (1998). ■■ Early demonstration of chimeric papillomavirus-like particles as immunogens.
    • (1998) Proc. Natl Acad. Sci. USA , vol.95 , pp. 1800-1805
    • Greenstone, H.L.1    Nieland, J.D.2    De Visser, K.E.3
  • 21
    • 22944451826 scopus 로고    scopus 로고
    • Murine polyomavirus 'virus-like' particles as vectors for gene and immune therapy and as vaccines against viral infections and cancer
    • Tegerstedt K, Franzén A, Andreasson K et al.: Murine polyomavirus 'virus-like' particles as vectors for gene and immune therapy and as vaccines against viral infections and cancer. Anticancer Res. 25(4), 2601-2608 (2005).
    • (2005) Anticancer Res. , vol.25 , Issue.4 , pp. 2601-2608
    • Tegerstedt, K.1    Franzén, A.2    Andreasson, K.3
  • 22
    • 0034006331 scopus 로고    scopus 로고
    • Studies on polyomavirus persistence and polyomavirus-induced tumor development in relation to the immune system
    • Berke Z, Dalianis T: Studies on polyomavirus persistence and polyomavirus-induced tumor development in relation to the immune system. Adv. Cancer Res. 79, 249-276 (2000).
    • (2000) Adv. Cancer Res. , vol.79 , pp. 249-276
    • Berke, Z.1    Dalianis, T.2
  • 23
    • 0000595685 scopus 로고    scopus 로고
    • Polyomavirinae: The viruses and their replication
    • (3rd Edition). Fields B, Knipe DM, Howley PM (Eds). Lippincott-Raven, New York, NY, USA
    • Cole CN: Polyomavirinae: the viruses and their replication. In: Virology (3rd Edition). Fields B, Knipe DM, Howley PM (Eds). Lippincott-Raven, New York, NY, USA, 2121-2174 (1996).
    • (1996) Virology , pp. 2121-2174
    • Cole, C.N.1
  • 24
    • 0024438462 scopus 로고
    • A single peptide derived from the sequence common to polyoma small and middle T-antigen induces immunity against polyoma tumors
    • First paper to our knowledge demonstrating tumor immunity by immunizing with a peptide from a virus tumor antigen
    • Ramqvist T, Reinholdsson G, Carlquist M, Bergman T, Dalianis T: A single peptide derived from the sequence common to polyoma small and middle T-antigen induces immunity against polyoma tumors. Virology 172(1), 359-362 (1989). ■ First paper to our knowledge demonstrating tumor immunity by immunizing with a peptide from a virus tumor antigen.
    • (1989) Virology , vol.172 , Issue.1 , pp. 359-362
    • Ramqvist, T.1    Reinholdsson, G.2    Carlquist, M.3    Bergman, T.4    Dalianis, T.5
  • 25
    • 0042691217 scopus 로고    scopus 로고
    • Gangliosides are receptors for murine polyoma virus and SV40
    • DOI 10.1093/emboj/cdg439
    • Tsai B, Gilbert JM, Stehle T, Lencer W, Benjamin TL, Rapaport TA: Gangliosides are receptors for murine polyoma virus and SV40. EMBO J. 22, 4346-4355 (2003). (Pubitemid 37087189)
    • (2003) EMBO Journal , vol.22 , Issue.17 , pp. 4346-4355
    • Tsai, B.1    Gilbert, J.M.2    Stehle, T.3    Lencer, W.4    Benjamin, T.L.5    Rapoport, T.A.6
  • 26
    • 0036711647 scopus 로고    scopus 로고
    • Analysis of mouse polyomavirus mutants with lesions in the minor capsid proteins
    • Mannova P, Liebl D, Krauzewicz N et al.: Analysis of mouse polyomavirus mutants with lesions in the minor capsid proteins. J. Gen. Virol. 83, 2309-2319 (2002).
    • (2002) J. Gen. Virol. , vol.83 , pp. 2309-2319
    • Mannova, P.1    Liebl, D.2    Krauzewicz, N.3
  • 27
    • 0018149164 scopus 로고
    • Chromatographic separation of the polyoma virus proteins and renaturation of the isolated VP1 major capsid protein
    • Original article demonstrating that the major capsid protein VP1 can spontaneously self assemble into VLPs
    • Brady JN, Consigli RA: Chromatographic separation of the polyoma virus proteins and renaturation of the isolated VP1 major capsid protein. J. Virol. 27, 436-442 (1978). ■■ Original article demonstrating that the major capsid protein VP1 can spontaneously self assemble into VLPs.
    • (1978) J. Virol. , vol.27 , pp. 436-442
    • Brady, J.N.1    Consigli, R.A.2
  • 29
    • 0000489478 scopus 로고
    • A pneumotropic virus isolated from C3H mice carrying the Bittner milk agent
    • Kilham L, Murphy HW: A pneumotropic virus isolated from C3H mice carrying the Bittner milk agent. Proc. Soc. Exp. Biol. Med. 82, 133-137 (1953).
    • (1953) Proc. Soc. Exp. Biol. Med. , vol.82 , pp. 133-137
    • Kilham, L.1    Murphy, H.W.2
  • 31
    • 0025726223 scopus 로고
    • Nucleotide sequence and genome organization of the murine polyomavirus, Kilham strain
    • Mayer M, Dörries K: Nucleotide sequence and genome organization of the murine polyomavirus, Kilham strain. Virology 181(2), 469-480 (1991).
    • (1991) Virology , vol.181 , Issue.2 , pp. 469-480
    • Mayer, M.1    Dörries, K.2
  • 32
    • 33745617952 scopus 로고    scopus 로고
    • Serological cross reactivity between polyomavirus capsids
    • Viscidi R, Clayman B: Serological cross reactivity between polyomavirus capsids. Adv. Exp. Med. Biol. 577, 73-84 (2006).
    • (2006) Adv. Exp. Med. Biol. , vol.577 , pp. 73-84
    • Viscidi, R.1    Clayman, B.2
  • 33
    • 34247158281 scopus 로고    scopus 로고
    • Identification of a third human polyomavirus
    • Allander T, Andreasson K, Gupta S et al.: Identification of a third human polyomavirus. J. Virol. 81,4130-4136 (2007).
    • (2007) J. Virol. , vol.81 , pp. 4130-4136
    • Allander, T.1    Andreasson, K.2    Gupta, S.3
  • 34
    • 34249650137 scopus 로고    scopus 로고
    • Identification of a novel polyomavirus from patients with acute respiratory tract infections
    • Gaynor AM, Nissen MD, Whiley DM et al.: Identification of a novel polyomavirus from patients with acute respiratory tract infections. PLoS Pathog. 3(5), E64 (2007).
    • (2007) PLoS Pathog. , vol.3 , Issue.5
    • Gaynor, A.M.1    Nissen, M.D.2    Whiley, D.M.3
  • 35
    • 39749113080 scopus 로고    scopus 로고
    • Clonal integration of a polyomavirus in human Merkel cell carcinoma
    • DOI 10.1126/science.1152586
    • Feng H, ChudaM, Chang Y, Moore PS: Clonal Integration of a polyomavirus in human Merkel cell carcinoma. Science 319(5866), 1096-1100 (2008). (Pubitemid 351300792)
    • (2008) Science , vol.319 , Issue.5866 , pp. 1096-1100
    • Feng, H.1    Shuda, M.2    Chang, Y.3    Moore, P.S.4
  • 36
    • 0001414735 scopus 로고    scopus 로고
    • Papillomaviruses and their replication
    • Howely PM (Ed.). Lippincott Williams & Wilkins, Philadelphia, PA, USA
    • Howely PM, Lowy DR: Papillomaviruses and their replication. In: Virology (Volume 2). Howely PM (Ed.). Lippincott Williams & Wilkins, Philadelphia, PA, USA, 2197-2229 (2001).
    • (2001) Virology , vol.2 , pp. 2197-2229
    • Howely, P.M.1    Lowy, D.R.2
  • 37
    • 0036559896 scopus 로고    scopus 로고
    • Papillomaviruses and cancer:from basic studies to clinical application
    • zur Hausen H: Papillomaviruses and cancer:from basic studies to clinical application. Nat. Rev. Cancer 2, 342-350 (2002).
    • (2002) Nat. Rev. Cancer , vol.2 , pp. 342-350
    • Zur Hausen, H.1
  • 38
    • 0033018458 scopus 로고    scopus 로고
    • New concepts on the role of human papillomavirus in cell regulation
    • Syrjanen SM and Syrjanen KJ: New concepts on the role of human papillomavirus in cell regulation. Ann. Med. 31, 175-187, 1999.
    • (1999) Ann. Med. , vol.31 , pp. 175-187
    • Syrjanen, S.M.1    Syrjanen, K.J.2
  • 39
    • 0027428414 scopus 로고
    • Efficient self-assembly of human papillomavirus type 16 L1 and L1-L2 into virus-like particles
    • Kirnbauer R, Taub J, Greenstone H et al.: Efficient self-assembly of human papillomavirus type 16 L1 and L1-L2 into virus-like particles. J. Virol. 67(12), 6929-6936 (1993).
    • (1993) J. Virol. , vol.67 , Issue.12 , pp. 6929-6936
    • Kirnbauer, R.1    Taub, J.2    Greenstone, H.3
  • 40
    • 0029913916 scopus 로고    scopus 로고
    • Epithelial cells display separate receptors for papillomavirus VLPs for soluble L1 protein
    • Qi YM, Peng SW, Hengst K et al.: Epithelial cells display separate receptors for papillomavirus VLPs for soluble L1 protein. Virology 216, 35-45, 1996.
    • (1996) Virology , vol.216 , pp. 35-45
    • Qi, Y.M.1    Peng, S.W.2    Hengst, K.3
  • 41
    • 0029025421 scopus 로고
    • Binding and internalization of human papillomavirus type 33 virus like particles by eukaryotic cells
    • Volpers C, Unckel F, Schirmacher P, Streek R, Sapp M: Binding and internalization of human papillomavirus type 33 virus like particles by eukaryotic cells. J. Virol. 69, 3258-3264 (1995).
    • (1995) J. Virol. , vol.69 , pp. 3258-3264
    • Volpers, C.1    Unckel, F.2    Schirmacher, P.3    Streek, R.4    Sapp, M.5
  • 43
    • 37049001852 scopus 로고    scopus 로고
    • Binding of human papilloma virus L1 virus-like particles to dendritic cells is mediated through heparan sulfates and induces immune activation
    • DOI 10.1016/j.imbio.2007.09.006, PII S0171298507001118, Macrophage and Dendritic Cells
    • de Witte L, Zoughlami Y, Aengeneyndt B, David G, van Kooyk Y, Gissmann L, Geijtenbeek TB: Binding of human papilloma virus L1 virus-like particles to dendritic cells is mediated through heparan sulfates and induces immune activation. Immunobiology 212(9-10), 679-691 (2007). (Pubitemid 350246260)
    • (2008) Immunobiology , vol.212 , Issue.9-10 , pp. 679-691
    • De Witte, L.1    Zoughlami, Y.2    Aengeneyndt, B.3    David, G.4    Van Kooyk, Y.5    Gissmann, L.6    Geijtenbeek, T.B.H.7
  • 44
    • 0035156505 scopus 로고    scopus 로고
    • Human papillomavirus infection requires cell surface heparan sulfate
    • Giroglou T, Florin L, Schäfer F, Streeck RE, Sapp M: Human papillomavirus infection requires cell surface heparan sulfate. J. Virol. 75(3), 1565-1570 (2001).
    • (2001) J. Virol. , vol.75 , Issue.3 , pp. 1565-1570
    • Giroglou, T.1    Florin, L.2    Schäfer, F.3    Streeck, R.E.4    Sapp, M.5
  • 45
    • 0037154719 scopus 로고    scopus 로고
    • Immunization of T-cell deficient mice against polyomavirus infection using viral pseudocapsids or temperature sensitive mutants
    • DOI 10.1016/S0264-410X(01)00506-0, PII S0264410X01005060
    • Heidari S, Vlastos A, Ramqvist T et al.: Immunization of T-cell deficient mice against polyomavirus infection using viral pseudocapsids or temperature sensitive mutants. Vaccine 20, 1571-1578 (2002). (Pubitemid 34169797)
    • (2002) Vaccine , vol.20 , Issue.11-12 , pp. 1571-1578
    • Heidari, S.1    Vlastos, A.2    Ramqvist, T.3    Clark, B.4    Griffin, B.E.5    Garcia, M.-I.6    Perez, M.7    Amati, P.8    Dalianis, T.9
  • 46
    • 0037410399 scopus 로고    scopus 로고
    • VP1 pseudocapsids, but not a glutathione-5-transferase VP1 fusion protein, prevent polyomavirus infection in a T-cell immune deficient experimental mouse model
    • Vlastos A, Andreasson K, Tegerstedt K et al.: VP1 pseudocapsids, but not a glutathione-5-transferase VP1 fusion protein, prevent polyomavirus infection in a T-cell immune deficient experimental mouse model. J. Med. Virol. 70, 293-300 (2003).
    • (2003) J. Med. Virol. , vol.70 , pp. 293-300
    • Vlastos, A.1    Andreasson, K.2    Tegerstedt, K.3
  • 47
    • 20944448032 scopus 로고    scopus 로고
    • Prophylactic quadrivalent human papillomavirus (types 6, 11, 16, and 18) L1 virus-like particle vaccine in young women: A randomised double-blind placebo-controlled multicentre Phase II efficacy trial
    • Successful vaccination in humans against human papillomavirus (HPV) type 6, 11, 16 and 18 with VLPs
    • Villa LL, Costa RL, Petta CA et al.: Prophylactic quadrivalent human papillomavirus (types 6, 11, 16, and 18) L1 virus-like particle vaccine in young women: a randomised double-blind placebo-controlled multicentre Phase II efficacy trial. Lancet Oncol. 6, 271-278 (2005). ■■ Successful vaccination in humans against human papillomavirus (HPV) type 6, 11, 16 and 18 with VLPs.
    • (2005) Lancet Oncol. , vol.6 , pp. 271-278
    • Villa, L.L.1    Costa, R.L.2    Petta, C.A.3
  • 48
    • 0037153042 scopus 로고    scopus 로고
    • A controlled trial of a human papillomavirus type 16 vaccine
    • First major clinical trial of a HPV VLP-based vaccine
    • Koutsky LA, Ault Ka, Wheeler CM et al.: A controlled trial of a human papillomavirus type 16 vaccine. N. Engl. J. Med. 347(21), 1645-1651 (2002). ■■ First major clinical trial of a HPV VLP-based vaccine.
    • (2002) N. Engl. J. Med. , vol.347 , Issue.21 , pp. 1645-1651
    • Koutsky, L.A.1    Ault, Ka.2    Wheeler, C.M.3
  • 49
    • 0035925074 scopus 로고    scopus 로고
    • Safety and immunogenicity trial in adult volunteers of a human papillomavirus 16 L virus-like particle vaccine
    • Harro CD, Pang YY, Roden RB et al.: Safety and immunogenicity trial in adult volunteers of a human papillomavirus 16 L virus-like particle vaccine. J. Natl Cancer Inst. 93(4), 284-292 (2001).
    • (2001) J. Natl Cancer Inst. , vol.93 , Issue.4 , pp. 284-292
    • Harro, C.D.1    Pang, Y.Y.2    Roden, R.B.3
  • 50
    • 33748701223 scopus 로고    scopus 로고
    • Cellular immune responses to HPV-18, -31, and -53 in healthy volunteers immunized with recombinant HPV-16 L1 virus-like particles
    • Pinto LA, Viscidi R, Harro CD et al.: Cellular immune responses to HPV-18, -31, and -53 in healthy volunteers immunized with recombinant HPV-16 L1 virus-like particles. Virology 353(2), 451-462 (2006).
    • (2006) Virology , vol.353 , Issue.2 , pp. 451-462
    • Pinto, L.A.1    Viscidi, R.2    Harro, C.D.3
  • 51
    • 33646058566 scopus 로고    scopus 로고
    • Sustained efficacy up to 4.5 years of a bivalent L1 virus-like particle vaccine against human papillomavirus types 16 and 18: Follow-up from a randomised control trial
    • Harper DM, Franco EL, Wheeler CM et al.: Sustained efficacy up to 4.5 years of a bivalent L1 virus-like particle vaccine against human papillomavirus types 16 and 18: follow-up from a randomised control trial. Lancet 367(9518), 1247-1255 (2006).
    • (2006) Lancet , vol.367 , Issue.9518 , pp. 1247-1255
    • Harper, D.M.1    Franco, E.L.2    Wheeler, C.M.3
  • 52
    • 55549137425 scopus 로고    scopus 로고
    • The future of cervical cancer prevention: Human papillomavirus vaccines
    • Cadman L: The future of cervical cancer prevention: human papillomavirus vaccines. J. Fam. Health Care 18(4), 131-132 (2008).
    • (2008) J. Fam. Health Care , vol.18 , Issue.4 , pp. 131-132
    • Cadman, L.1
  • 53
    • 0031579249 scopus 로고    scopus 로고
    • Sequence close to the N-terminus of L2 protein is displayed on the surface of bovine papillomavirus type 1 virions
    • Liu WJ, Gissmann L, Sun XY et al.: Sequence close to the N-terminus of L2 protein is displayed on the surface of bovine papillomavirus type 1 virions. Virology 227(2), 474-483 (1997).
    • (1997) Virology , vol.227 , Issue.2 , pp. 474-483
    • Liu, W.J.1    Gissmann, L.2    Sun, X.Y.3
  • 54
    • 20444396970 scopus 로고    scopus 로고
    • Cross-neutralization of cutaneous and mucosal papillomavirus types with anti-sera to the amino terminus of L2
    • Pastrana DV, Gambhira R, Buck CB et al.: Cross-neutralization of cutaneous and mucosal papillomavirus types with anti-sera to the amino terminus of L2. Virology 337(2), 365-372 (2005).
    • (2005) Virology , vol.337 , Issue.2 , pp. 365-372
    • Pastrana, D.V.1    Gambhira, R.2    Buck, C.B.3
  • 55
    • 0034630951 scopus 로고    scopus 로고
    • Minor capsid protein of human genital papillomaviruses contains subdominant, cross-neutralizing epitopes
    • DOI 10.1006/viro.2000.0272
    • Roden RB, Yutzy WHT, Fallon R et al.: Minor capsid protein of human genital papillomaviruses contains subdominant, cross-neutralizing epitopes. Virology 270(2), 254-257 (2000). (Pubitemid 30333671)
    • (2000) Virology , vol.270 , Issue.2 , pp. 254-257
    • Roden, R.B.S.1    Yutzy IV, W.H.2    Fallon, R.3    Inglis, S.4    Lowy, D.R.5    Schiller, J.T.6
  • 56
    • 41849151459 scopus 로고    scopus 로고
    • Modification of human papillomavirus-like particle vaccine by insertion of the cross-reactive L2-epitopes
    • Kondo K, Ochi H, Matsumoto T, Yoshikawa H, Kanda T: Modification of human papillomavirus-like particle vaccine by insertion of the cross-reactive L2-epitopes. J. Med. Virol. 80, 841-846 (2008).
    • (2008) J. Med. Virol. , vol.80 , pp. 841-846
    • Kondo, K.1    Ochi, H.2    Matsumoto, T.3    Yoshikawa, H.4    Kanda, T.5
  • 57
    • 33846875433 scopus 로고    scopus 로고
    • A papillomavirus-like particle (VLP) vaccine displaying HPV16 L2 epitopes induces cross-neutralizing antibodies to HPV11
    • Slupetzky K, Gambhira R, Culp TD et al.: A papillomavirus-like particle (VLP) vaccine displaying HPV16 L2 epitopes induces cross-neutralizing antibodies to HPV11. Vaccine 25(11), 2001-2010 (2007).
    • (2007) Vaccine , vol.25 , Issue.11 , pp. 2001-2010
    • Slupetzky, K.1    Gambhira, R.2    Culp, T.D.3
  • 58
    • 16344385992 scopus 로고    scopus 로고
    • Murine polyomarivus-VP1 virus-like particles immunize against some polyomavirus-induced tumours
    • Vlastos Franzén A, Tegerstedt K, Hollanderovi D, Forstová J, Ramqvist T, Dalianis T: Murine polyomavirus VP1 virus-like particles immunize against some polyomvirus induced tumors. In Vivo 19(2), 323-326 (2005). (Pubitemid 40467615)
    • (2005) In Vivo , vol.19 , Issue.2 , pp. 323-326
    • Franzen, A.V.1    Tegerstedt, K.2    Hollanderova, D.3    Forstova, J.4    Ramqvist, T.5    Dalianis, T.6
  • 59
    • 0034886372 scopus 로고    scopus 로고
    • Kinetic analysis of the steps of the polyomavirus lytic cycle
    • DOI 10.1128/JVI.75.18.8368-8379.2001
    • Chen L, Fluck M: Kinetic analysis of the steps of the polyomavirus lytic cycle. J. Virol. 75, 8368-8379 (2001). (Pubitemid 32768941)
    • (2001) Journal of Virology , vol.75 , Issue.18 , pp. 8368-8379
    • Chen, L.1    Fluck, M.2
  • 60
    • 77953400128 scopus 로고    scopus 로고
    • ink4a immunohistochemistry staining predicts response to radiotherapy and is is similar to human papilloma virus (HPV) detection by PCR a favourable prognostic factor in tonsillar carcinoma
    • ink4a immunohistochemistry staining predicts response to radiotherapy and is is similar to human papilloma virus (HPV) detection by PCR a favourable prognostic factor in tonsillar carcinoma. Anticancer Research. 4375-4383 (2005).
    • (2005) Anticancer Research , pp. 4375-4383
    • Dahlstrand, H.1    Björneståhl, L.2    Lindquist, D.3    Dalianis, T.4    Munck-Wikland, E.5    Elmberger, G.6
  • 61
    • 34547912100 scopus 로고    scopus 로고
    • Effect of human papillomavirus 16/18 Ll viruslike particle vaccine among young women with preexisting infection: A randomized trial
    • Hildesheim A, Herrero R, Wacholder S et al.: Effect of human papillomavirus 16/18 Ll viruslike particle vaccine among young women with preexisting infection: a randomized trial. JAMA 298(7), 743-753 (2007).
    • (2007) JAMA , vol.298 , Issue.7 , pp. 743-753
    • Hildesheim, A.1    Herrero, R.2    Wacholder, S.3
  • 63
    • 0036849734 scopus 로고    scopus 로고
    • Human papillomavirus immortalization and transformation functions
    • DOI 10.1016/S0168-1702(02)00190-9, PII S0168170202001909
    • Munger K, Howley PM: Human papillomavirus immortalization and transformation functions. Virus Res. 89(2), 213-228 (2002). (Pubitemid 35351540)
    • (2002) Virus Research , vol.89 , Issue.2 , pp. 213-228
    • Munger, K.1    Howley, P.M.2
  • 64
    • 0036986254 scopus 로고    scopus 로고
    • Comparison of human papillomavirus type 16 L1 chimeric virus-like particles versus L1/L2 chimeric virus-like particles in tumor prevention
    • Wakabayashi MT, DA Silva DM, Potkul RK, Kast WM: Comparison of human papillomavirus type 16 L1 chimeric virus-like particles versus L1/L2 chimeric virus-like particles in tumor prevention. Intervirology 45(4-6), 300-307 (2002).
    • (2002) Intervirology , vol.45 , Issue.4-6 , pp. 300-307
    • Wakabayashi, M.T.1    Da Silva, D.M.2    Potkul, R.K.3    Kast, W.M.4
  • 65
    • 0033167196 scopus 로고    scopus 로고
    • Chimeric virus-like particles of the human papillomavirus type 16 (HPV 16) as a prophylactic and therapeutic vaccine
    • Jochmus I, Schafer K, Faath S, Muller M, Gissmann L: Chimeric virus-like particles of the human papillomavirus type 16 (HPV 16) as a prophylactic and therapeutic vaccine. Arch. Med. Res. 30(4), 269-274 (1999).
    • (1999) Arch. Med. Res. , vol.30 , Issue.4 , pp. 269-274
    • Jochmus, I.1    Schafer, K.2    Faath, S.3    Muller, M.4    Gissmann, L.5
  • 66
    • 0035871993 scopus 로고    scopus 로고
    • HPV16 L1E7 chimeric virus-like particles induce specific HLA-restricted T cells in humans after in vitro vaccination
    • Kaufmann AM, Nieland J, Schinz M et al.: HPV16 L1E7 chimeric virus-like particles induce specific HLA-restricted T cells in humans after in vitro vaccination. Int. J. Cancer 92(2), 285-293 (2001).
    • (2001) Int. J. Cancer , vol.92 , Issue.2 , pp. 285-293
    • Kaufmann, A.M.1    Nieland, J.2    Schinz, M.3
  • 67
    • 36248945563 scopus 로고    scopus 로고
    • Vaccination trial with HPV16 L1E/ chimeric virus-like particles in women suffering from high grade intraepithelial neoplasia (CIN 2/3)
    • Kaufman AM, Nieland JD, Jochmus I et al.: Vaccination trial with HPV16 L1E/ chimeric virus-like particles in women suffering from high grade intraepithelial neoplasia (CIN 2/3). Int. J. Cancer 121, 2794-2800 (2007).
    • (2007) Int. J. Cancer , vol.121 , pp. 2794-2800
    • Kaufman, A.M.1    Nieland, J.D.2    Jochmus, I.3
  • 68
    • 0037866949 scopus 로고    scopus 로고
    • Heterologous boosting increases immunogenicity of chimeric papillomavirus virus-like particle vaccines
    • Da Silva DM, Schiller JT, Kast WM: Heterologous boosting increases immunogenicity of chimeric papillomavirus virus-like particle vaccines. Vaccine 21(23), 3219-3227 (2003).
    • (2003) Vaccine , vol.21 , Issue.23 , pp. 3219-3227
    • Da Silva, D.M.1    Schiller, J.T.2    Kast, W.M.3
  • 69
    • 37049183697 scopus 로고
    • Human breast cancer: Correlation of relapse and survival with amplification of the HER-2/neu oncogene
    • Slamon DJ, Clark GM, Wong SG et al.: Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene. Science 235(4785), 177-182 (1987).
    • (1987) Science , vol.235 , Issue.4785 , pp. 177-182
    • Slamon, D.J.1    Clark, G.M.2    Wong, S.G.3
  • 70
    • 0036391523 scopus 로고    scopus 로고
    • Cellular immunity to the Her-2/neu protooncogene
    • Kiessling R, Wei WZ, Herrmann F et al.: Cellular immunity to the Her-2/neu protooncogene. Adv. Cancer Res. 85, 101-144 (2002).
    • (2002) Adv. Cancer Res. , vol.85 , pp. 101-144
    • Kiessling, R.1    Wei, W.Z.2    Herrmann, F.3
  • 71
    • 58149375091 scopus 로고    scopus 로고
    • Murine pneumotropic virus chimeric Her2/neu virus-like particles as prophylactic and therapeutic vaccines against Her2/neu expressing tumours
    • Andreasson K, Tegerstedt K, Eriksson O et al.: Murine pneumotropic virus chimeric Her2/neu virus-like particles as prophylactic and therapeutic vaccines against Her2/neu expressing tumours. Int J. Cancer 124(1), 150-156 (2008).
    • (2008) Int J. Cancer , vol.124 , Issue.1 , pp. 150-156
    • Andreasson, K.1    Tegerstedt, K.2    Eriksson, O.3
  • 72
    • 0035340806 scopus 로고    scopus 로고
    • Papillomavirus-like particles induce acute activation of dendritic cells
    • Lenz P, Day PM, Pang YY et al.: Papillomavirus-like particles induce acute activation of dendritic cells. J. Immunol. 166(9), 5346-5355 (2001).
    • (2001) J. Immunol. , vol.166 , Issue.9 , pp. 5346-5355
    • Lenz, P.1    Day, P.M.2    Pang, Y.Y.3
  • 73
    • 18844370878 scopus 로고    scopus 로고
    • Papillomavirus virus-like particles induce cytokines characteristic of innate immune responses in plasmacytoid dendritic cells
    • Lenz P, Lowy DR, Schiller JT: Papillomavirus virus-like particles induce cytokines characteristic of innate immune responses in plasmacytoid dendritic cells. Eur. J. Immunol. 35(5), 1548-1556 (2005).
    • (2005) Eur. J. Immunol. , vol.35 , Issue.5 , pp. 1548-1556
    • Lenz, P.1    Lowy, D.R.2    Schiller, J.T.3
  • 74
    • 33749537853 scopus 로고    scopus 로고
    • Virus-like particles derived from major capsid protein VP1 of different polyomaviruses differ in their ability to induce maturation in human dendritic cells
    • Gedvilaite A, Dorn DC, Sasnauskas K et al.: Virus-like particles derived from major capsid protein VP1 of different polyomaviruses differ in their ability to induce maturation in human dendritic cells. Virology 354(2), 252-260 (2006).
    • (2006) Virology , vol.354 , Issue.2 , pp. 252-260
    • Gedvilaite, A.1    Dorn, D.C.2    Sasnauskas, K.3
  • 75
    • 33846707566 scopus 로고    scopus 로고
    • Murine polyomavirus-like particles induce maturation of bone marrow-derived dendritic cells and proliferation of T cells
    • Berl.
    • Bickert T, Wohlleben G, Brinkman M et al.: Murine polyomavirus-like particles induce maturation of bone marrow-derived dendritic cells and proliferation of T cells. Med. Microbiol. Immunol. (Berl.) 196(1), 31-39 (2007).
    • (2007) Med. Microbiol. Immunol. , vol.196 , Issue.1 , pp. 31-39
    • Bickert, T.1    Wohlleben, G.2    Brinkman, M.3
  • 76
    • 34347387533 scopus 로고    scopus 로고
    • Dendritic cells loaded with polyomavirus VP1/VP2Her2 virus-like particles (VLPs) efficiently prevent outgrowth of a Her2/neu expressing tumor without inducing high anti-VLP serum titers
    • Tegerstedt K, Franzén A, Ramqvist T, Dalianis T: Dendritic cells loaded with polyomavirus VP1/VP2Her2 virus-like particles (VLPs) efficiently prevent outgrowth of a Her2/neu expressing tumor without inducing high anti-VLP serum titers. Cancer Immunol. Immunotherapy 56(9), 1335-1344, (2007).
    • (2007) Cancer Immunol. Immunotherapy , vol.56 , Issue.9 , pp. 1335-1344
    • Tegerstedt, K.1    Franzén, A.2    Ramqvist, T.3    Dalianis, T.4
  • 77
    • 0037359309 scopus 로고    scopus 로고
    • Interaction of papillomavirus virus-like particles with human myeloid antigen-presenting cells
    • Lenz P, Thompson CD, Day PM et al.: Interaction of papillomavirus virus-like particles with human myeloid antigen-presenting cells. Clin. Immunol. 106(3), 231-237 (2003).
    • (2003) Clin. Immunol. , vol.106 , Issue.3 , pp. 231-237
    • Lenz, P.1    Thompson, C.D.2    Day, P.M.3
  • 78
    • 0037742398 scopus 로고    scopus 로고
    • Differential uptake and cross-presentation of human papillomavirus virus-like particles by dendritic cells and Langerhans cells
    • Fausch SC, Da Silva DM, Kast WM: Differential uptake and cross-presentation of human papillomavirus virus-like particles by dendritic cells and Langerhans cells. Cancer Res. 63(13), 3478-3482 (2003).
    • (2003) Cancer Res. , vol.63 , Issue.13 , pp. 3478-3482
    • Fausch, S.C.1    Da Silva, D.M.2    Kast, W.M.3
  • 79
    • 12944291025 scopus 로고    scopus 로고
    • Overcoming antigen masking of anti-amyloidbeta antibodies reveals breaking of B cell tolerance by virus-like particles in amyloidbeta immunized amyloid precursor protein transgenic mice
    • Li Q, Cao C, Chackerian B et al.: Overcoming antigen masking of anti-amyloidbeta antibodies reveals breaking of B cell tolerance by virus-like particles in amyloidbeta immunized amyloid precursor protein transgenic mice. BMC Neurosci. 5, 21 (2004).
    • (2004) BMC Neurosci. , vol.5 , pp. 21
    • Li, Q.1    Cao, C.2    Chackerian, B.3
  • 80
    • 1842431907 scopus 로고    scopus 로고
    • Induction of Autoantibodies to CCR5 in Macaques and Subsequent Effects Upon Challenge with An R5-Tropic Simian/Human Immunodeficiency Virus
    • DOI 10.1128/JVI.78.8.4037-4047.2004
    • Chackerian B, Briglio L, Albert PS, Lowy DR, Schiller JT: Induction of autoantibodies to CCR5 in macaques and subsequent effects upon challenge with an R5-tropic simian/human immunodeficiency virus. J. Virol. 78(8), 4037-4047 (2004). (Pubitemid 38437210)
    • (2004) Journal of Virology , vol.78 , Issue.8 , pp. 4037-4047
    • Chackerian, B.1    Briglio, L.2    Albert, P.S.3    Lowy, D.R.4    Schiller, J.T.5
  • 81
    • 0036884940 scopus 로고    scopus 로고
    • Determinants of autoantibody induction by conjugated papillomavirus virus-like particles
    • Chackerian B, Lenz P, Lowy DR, Schiller JT: Determinants of autoantibody induction by conjugated papillomavirus virus-like particles. J. Immunol. 169(11), 6120-6126 (2002). (Pubitemid 36903455)
    • (2002) Journal of Immunology , vol.169 , Issue.11 , pp. 6120-6126
    • Chackerian, B.1    Lenz, P.2    Lowy, D.R.3    Schiller, J.T.4


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