Murine polyomavirus-like particles induce maturation of bone marrow-derived dendritic cells and proliferation of T cells

Medical Microbiology and Immunology

Volumn 196, Issue 1, 2007, Pages 31-39

  Bickert, Thomas ^a,c   Wohlleben, Gisela ^a   Brinkman, Marc ^b   Trujillo Vargas, Claudia M ^a,d   Ruehland, Claus ^b   Reiser, Christian O A ^b   Hess, Juergen ^b   Erb, Klaus J ^a  

^a UNIVERSITY OF WÜRZBURG   (Germany)

^b Responsif GmbH   (Germany)

^c BERNHARD NOCHT INSTITUTE FOR TROPICAL MEDICINE   (Germany)

^d UNIVERSIDAD DE ANTIOQUIA   (Colombia)

Author keywords

Chimeric PLPs; Dendritic cells; Maturation; T cell proliferation; Virus like particles

Indexed keywords

B7 ANTIGEN; CD40 ANTIGEN; CD86 ANTIGEN; LYMPHOCYTE SURFACE MARKER; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; OVALBUMIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BONE MARROW CELL; BONE MATURATION; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL PROLIFERATION; CONTROLLED STUDY; DENDRITIC CELL; FEMALE; IN VITRO STUDY; NONHUMAN; PRIORITY JOURNAL; T LYMPHOCYTE; VIRUS LIKE AGENT;

ADJUVANTS, IMMUNOLOGIC; ANIMALS; ANTIGEN PRESENTATION; ANTIGENS, CD; CYTOKINES; DENDRITIC CELLS; HISTOCOMPATIBILITY ANTIGENS CLASS I; HISTOCOMPATIBILITY ANTIGENS CLASS II; LYMPHOCYTE ACTIVATION; MICE; MICE, INBRED C57BL; OVALBUMIN; POLYOMAVIRUS; T-LYMPHOCYTES;

EID: 33846707566     PISSN: 03008584     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00430-006-0026-x     Document Type: Article

References (31)

1. Abbing A, Blaschke UK, Grein S, Kretschmar M, Stark CMB, Thies MJW, Walter J, Weigand M, Woith DC, Hess J, Reiser COA (2004) Efficient intracellular delivery of a protein and a low molecular weight substance via recombinant polyomavirus-like particles. J Biol Chem 279:27410-27421
2. Beyer T, Herrmann M, Reiser C, Bertling W, Hess J (2001) Bacterial carriers and virus-like-particles as antigen delivery devices: role of dendritic cells in antigen presentation. Curr Drug Targets Infect Disord 1(3):287-302
3. Boisgerault F, Moron G, Leclerc C (2002) Virus-like particles: a new family of delivery systems. Expert Rev Vaccines 1:101-109
4. Boura E, Liebl D, Spisek R, Fric J, Marek M, Stokrova J, Holan V, Forstova J (2005) Polyomavirus EGFP-pseudocapsids: analysis of model particles for introduction of proteins and peptides into mammalian cells. FEBS Lett 579(29):6549-6558
5. Brinkman M, Walter J, Jennes I, Neugebauer M, Bertling W, Grein S, Thies MJW, Weigand M, Beyer T, Herrmann M, Reiser COA, Hess J (2004) Recombinant murine polyoma virus-like-particles induce protective anti-tumour immunity. Lett Drug Des Discov 1:137-147
6. Brinkman M, Walter J, Grein S, Thies MJW, Schulz T, Herrmann M, Reiser COA, Hess J (2005) Beneficial therapeutic effects with different particulate structures of murine polyomavirus VP1-coat protein carrying self or non-self CD8 T cell epitopes against murine melanoma. Cancer Immunol Immunother 54(6):611-622
7. Carbone FR, Belz GT, Heath WR (2004) Transfer of antigen between migrating and lymph node-resident DCs in peripheral T cell tolerance and immunity. Trends Immunol 25:655-658
8. Engelmayer J, Larsson M, Subklewe M, Chahroudi A, Cox I, Steinman RM, Bhardawaj N (1999) Vaccinia virus inhibits the maturation of human dendritic cells: a novel mechanism of immune evasion. J Immunol 163:6762-6768
9. Gao B, Tsan MF (2003) Recombinant human heat shock protein 60 does not induce the release of tumor necrosis factor alpha from murine macrophages. J Biol Chem 278(25):22523-22529
10. Gilbert JM, Goldberg IG, Benjamin TL (2003) Cell penetration and trafficking of polyomavirus. J Virol 77(4):2615-2622
11. Greenstone HL, Nieland JD, de Visser KE, de Brujin MLH, Kirnbauer R, Roden RBS, Lowy DR, Kast M, Schiller JT (1998) Chimeric papillomavirus virus-like particles elicit antitumor immunity against the E7 oncoprotein in an HPV16 tumor model. Proc Natl Acad Sci USA 95:1800-1805
12. Gurnani K, Kennedy J, Sad S, Sprott GD, Krishnan L (2004) Phosphatidylserine receptor-mediated recognition of archaeosome adjuvant promotes endocytosis and MHC class I cross-presentation of the entrapped antigen by phagosome-to-cytosol transport and classical processing. J Immunol 173:566-578
13. Lenz P, Elbe G, Stingl G, Bergstresser PR (1996) MHC class I expression on dendritc cells is sufficient to sensitize for transplantation immunity. J Invest Dermatol 107:844-848
14. Lenz P, Day PM, Pang YY, Frye SA, Jensen PN, Lowy DR, Schiller JT (2001) Papillomavirus-like particles induce acute activation of dendritic cells. J Immunol 166(9):5346-5355
15. Lenz P, Thompson CD, Day PM, Bacot SM, Lowy DR, Schiller JT (2003) Interaction of papillomavirus virus-like particles with human myeloid antigen-presenting cells. Clin Immunol 106(3):231-237
16. Lutz M, Kukutsch N, Ogilvie A, Rossner S, Koch F, Romani N, Schuler G (1999) An advanced culture method for generating large quantities of highly pure dendritic cells from mouse bone marrow. J Immunol Methods 223:77-92
17. Moron VG, Rueda P, Sedlik C, Leclerc C (2003) In vivo, dendritic cells can cross-present virus-like particles using an endosome-to-cytosol pathway. J Immunol 171(5):2242-2250
18. Nandi D, Tahiliani P, Kumar A, Chandu D (2006) The ubiquitin-proteasome system. J Biosci 31:137-155
19. Reichel C, Brinkman M, Ruehland C, Reiser COA, Hess J (2006) Heterologous virus-like-particles: recombinant nanosystems as versatile antigen delivery devices for immune intervention. Curr Nanosci (in press)
20. Salio M, Cella M, Suter M, Lanzavecchia A (1999) Inhibition of dendritic cell maturation by herpes simplex virus. Eur J Immunol 29:3245-3253
21. Schirmbeck R, Bohm W, Reimann J (1994) Injection of detergent-denatured ovalbumin primes murine class I-restricted cytotoxic T cells in vivo. Eur J Immunol 24:2068-2072
22. Sedlik C, Saron M, Sarraseca J, Casal I, Leclerc C (1997) Recombinant parvovirus-like particles as an antigen carrier: a novel nonreplicative exogenous antigen to elicit protective antiviral cytotoxic T cells. Proc Natl Acad Sci USA 94:7503-7508
23. Servet-Delprat C, Vidalain PO, Bausinger H, Manie S, Le Deist F, Azocar O, Hanau D, Fischer A, Rabourdin-Combe C (2000) Measles virus induces abnormal differentiation of CD40-ligand-activated human dendritic cells. J Immunol 164:1753-1760
24. Smith AE, Lilie H, Helenius A (2003) Ganglioside-dependent cell attachment and endocytosis of murine polyomavirus-like particles. FEBS Lett 555:199-203
25. Strehl B, Seifert U, Kruger E, Heink S, Kuckelkorn U, Kloetzel PM (2005) Interferon-gamma, the functional plasticity of the ubiquitin-proteasome system, and the MHC class I antigen processing. Immunol Rev 207:19-30
26. Tegerstedt K, Lindencrona JA, Curcio C, Andreasson K, Tullus C, Forni G, Dalianis T, Kiessling R, Ramqvist T (2005) Single vaccination with polyomavirus VP1/VP2Her2 virus-like particles prevents outgrowth of HER-2/neu-expressing tumors. Cancer Res 65(13):5953-5957
27. Trujillo-Vargas CM, Mayer KD, Bickert T, Palmetshofer A, Grunewald S, Ramirez-Pineda JR, Polte T, Hansen G, Wohlleben G, Erb KJ (2005) Vaccinations with T-helper type 1 directing adjuvants have different suppressive effects on the development of allergen-induced T-helper type 2 responses. Clin Exp Allergy 35:1003-1013
28. Tsai B, Gilbert JM, Stehle T, Lencer W, Benjamin TL, Rapoport TA (2003) Gangliosides are receptors for murine polyoma virus and SV40. EMBO J 22(17):4346-4355
29. Velupillai P, Garcea RL, Benjamin TL (2006) Polyoma virus-like particles elicit polarized cytokine responses in APCs from tumor-susceptible and -resistant mice. J Immunol 176(2):1148-1153
30. Williams TM, Lisanti MP (2004) The caveolin genes: from cell biology to medicine. Ann Med 36:584-595
31. Wohlleben G, Müller J, Tatsch U, Hambrecht C, Herz U, Renz H, Schmitt E, Moll H, Erb KJ (2003) Influenza A virus infection inhibits the efficient recruitment of Th2 cells into the airways and the development of airway eosinophilia. J Immunol 170:4601-4611