Non-invasive sensors as enablers of "smart" disposables

BioProcess International

Volumn 7, Issue SUPPL.1, 2009, Pages 24-27

  Rao, Govind ^a   Kostov, Yordan ^a   Moreira, Antonio ^a   Frey, Douglas ^a   Hanson, Michael ^b   Jornitz, Maik ^c   Reif, Oscar Werner ^c   Baumfalk, Reinhard ^c   Qualitz, Joseph ^d  

^a University of Marylandw Baltimore County   (United States)

^b PFIZER INC   (United States)

^c SARTORIUS STEDIM BIOTECH GMBH   (Germany)

^d Fluorometrix ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOPROCESS; BIOTECHNOLOGY; DISPOSABLE EQUIPMENT; NON INVASIVE PROCEDURE; PURIFICATION; SENSOR; SHORT SURVEY;

EID: 77953449206     PISSN: 15426319     EISSN: None     Source Type: Trade Journal    
DOI: None     Document Type: Short Survey

References (9)

1. Food and Drug Administration. PAT - A Framework for Innovative Pharmaceutical Development, Manufacturing and Quality Assurance (2004): www.fda.gov/cder/guidance.
2. Brorson K, et al. Considerations for Developing Biopharmaceuticals: The FDA Perspective. Modern Biopharmaceuticals (Wiley-VCH, Weinheim, Germany, 2005).
3. Food and Drug Administration. Guideline on General Principles of Process Validation (1987): www.fda.gov/cder/guidance.
4. Ge X, et al. Validation of an Optical Sensor-Based High-Throughput Bioreactor System for Mammalian Cell Culture. J. Biotechnol. 122 2006: 293-306.
5. Harms P, et al. Design and Performance of a 24 Station High Throughput Microbioreactor. Biotechnol. Bioeng. 93 2006: 6-13.
6. Hanson MA, et al. Comparisons of Optical pH and Dissolved Oxygen Sensors with Traditional Electrochemical Probes During Mammalian Cell Culture. Biotechnol. Bioeng. 97 2007: 833-841.
7. Kondragunta B, et al. Advances in Clone Selection Using High-throughput Bioreactors. Manuscript submitted to Biotechnol. Bioeng.
8. US Patent 6673532. Bioreactor and Bioprocessing Technique.
9. US Patent 7041493. Bioreactor and Bioprocessing Technique.