Lavandulyl flavonoids from sophora flavescens suppress lipopolysaccharide-induced activation of nuclear factor-κB and mitogen-activated protein kinases in RAW264.7 cells

Biological and Pharmaceutical Bulletin

Volumn 33, Issue 6, 2010, Pages 1019-1023

  Han, Jong Min ^a   Jin, Yue Yan ^a   Kim, Hoi Young ^b   Park, Ki Hun ^b   Lee, Woo Song ^a   Jeong, Tae Sook ^a  

^a Korea Research Institute of Bioscience and Biotechnology (KRIBB)   (South Korea)

^b Gyeongsang National University   (South Korea)

Author keywords

Lavandulyl flavonoid; Mitogen acti vated protein kinase; Nitric oxide; Nuclear factor B; Reactive oxygen species; Sophora flavescens

Indexed keywords

CYTOKINE; FLAVONOID; I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 1BETA; KURARIDIN; KURARINONE; LAVANDULYL FLAVONOID; LIPOPOLYSACCHARIDE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; MONOCYTE CHEMOTACTIC PROTEIN 1; NITRIC OXIDE; REACTIVE OXYGEN METABOLITE; STRESS ACTIVATED PROTEIN KINASE; SYNAPTOTAGMIN I; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL LINE; CELL STRAIN RAW264.7; CONTROLLED STUDY; DRUG EFFECT; DRUG STRUCTURE; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; GEL MOBILITY SHIFT ASSAY; INHIBITION KINETICS; MACROPHAGE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN DEGRADATION; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SOPHORA; SOPHORA FLAVESCENS; WESTERN BLOTTING;

ANIMALS; ANTI-INFLAMMATORY AGENTS; ANTIOXIDANTS; CELL LINE; CHALCONES; FLAVONOIDS; INFLAMMATION MEDIATORS; LIPOPOLYSACCHARIDES; MICE; MITOGEN-ACTIVATED PROTEIN KINASES; MONOTERPENES; NF-KAPPA B; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE II; PLANT EXTRACTS; REACTIVE OXYGEN SPECIES; SOPHORA;

EID: 77953434456     PISSN: 09186158     EISSN: 13475215     Source Type: Journal    
DOI: 10.1248/bpb.33.1019     Document Type: Article

References (30)

1. Yokoyama M., Curr. Opin. Pharmacol., 4, 110-115 (2004).
2. Gutteridge J. M., Chem. Biol. Interact., 91, 133-140 (1994).
3. Jope R. S., Zhang L., Song L., Arch. Biochem. Biophys., 376, 365-370 (2000).
4. Go Y. M., Patel R. P., Maland M. C., Park H., Beckman J. S., Darley-Usmar V. M., Jo H., Am. J. Physiol., 277, H1647-H1653 (1997).
5. Ghosh S., May M. J., Kopp E. B., Annu. Rev. Immunol., 16, 225-260 (1998).
6. Li Q., Verma I. M., Nat. Rev. Immunol., 2, 25-34 (2002).
7. Pearson G., Robinson F., Beers Gibson T., Xu B. E., Karandikar M., Berman K., Cobb M. H., Endocr. Rev., 22, 153-183 (2001).
8. Ajizian S. J., English B. K., Meals E. A., J. Infect. Dis., 179, 939-944 (1999).
9. Tang W., Eisenbrand G., Chinese Drugs of Plant Origin: Chemistry, Pharmacology, and Use in Traditional and Modern Medicine, Springer-Verlag, Berlin, 1992, pp. 931-943.
10. Lee H. S., Ko H. R., Ryu S. Y., Oh W. K., Kim B. Y., Ahn S. C., Mheen T. I., Ahn J. S., Planta Med., 63, 266-268 (1997).
11. Chi Y. S., Jong H. G., Son K. H., Chang H. W., Kang S. S., Kim H. P., Biochem. Pharmacol., 62, 1185-1191 (2001).
12. Lee S. W., Lee H. S., Nam J. Y., Kwon O. E., Baek J. A., Chang J. S., Rho M. C., Kim Y. K., J. Ethnopharmacol., 97, 515-519 (2005).
13. Kim J. H., Ryu Y. B., Kang N. S., Lee B. W., Heo J. S., Jeong I.-Y., Park K. H., Biol. Pharm. Bull., 29, 302-305 (2006).
14. Ding P.-L., Liao Z.-X., Huang H., Zhou P., Chen D.-F., Bioorg. Med. Chem. Lett., 16, 1231-1235 (2006).
15. Harborne J. B., Williams C. A., Phytochemistry, 55, 481-504 (2000).
16. Kim H. K., Cheon B. S., Kim Y. H., Kim S. Y., Kim H. P., Biochem. Pharmacol., 58, 759-765 (1999).
17. Suzuki F., Okayasu H., Tashiro M., Hashimoto K., Yokote Y., Akahane K., Hongo S., Sakagami H., Anticancer Res., 22, 2719-2724 (2002).
18. Du J., He Z. D., Jiang R. W., Ye W. C., Xu H. X., But P. P., Phytochemistry, 62, 1235-1238 (2003).
19. Piao X.-L., Piao X. S., Kim S. W., Park J. H., Kim H. Y., Cai S.-Q., Biol. Pharm. Bull., 29, 1911-1915 (2006).
20. Jung H. A., Jeong D.-M., Chung Y. H., Lim H. A., Kim J. Y., Yoon N. Y., Choi J. S., Biol. Pharm. Bull., 31, 908-915 (2008).
21. Jeong T. S., Ryu Y. B., Kim H. Y., Curtis-Long M. J., An S., Lee J. W., Lee W. S., Park K. H., Biol. Pharm. Bull., 31, 2097-2102 (2008).
22. Son J. K., Park J. S., Kim J. A., Kim Y., Chung S. R., Lee S. H., Planta Med., 69, 559-561 (2003).
23. Kim D. W., Choi Y. S., Son K. H., Chang H. W., Kim J. S., Kang S. S., Kim H. P., Arch. Pharm. Res., 25, 329-335 (2002).
24. Hobbs A. J., Higgs A., Moncada S., Annu. Rev. Pharmacol. Toxicol., 39, 191-220 (1999).
25. Bogdan C., Nat. Immunol., 2, 907-916 (2001).
26. Luoma J. S., Stralin P., Marklund S. L., Hiltunen T. P., Sarkioja T., Yla-Herttuala S., Arterioscler. Thromb. Vasc. Biol., 18, 9157-9167 (1998).
27. Guslandi M., Eur. J. Clin. Invest., 28, 904-907 (1998).
28. Surh Y. J., Chun K. S., Cha H. H., Han S. S., Keum Y. S., Park K. K., Lee S. S., Mutat. Res., 480-481, 243-268 (2001).
29. Xie Q. W., Kashiwabara Y., Nathan C., J. Biol. Chem., 269, 4705-4708 (1994).
30. Karin M., J. Biol. Chem., 274, 27339-27342 (1999).